Báo cáo khoa học: Structures of type B ribose 5-phosphate isomerase from Trypanosoma cruzi shed light on the determinants of sugar specificity in the structural family ppt

... 6-carbon sugar. The combined information allows us to distinguish the two types of < /b> specificity patterns in other available sequences. The results obtained in the present study provide insights into ... Rpi, ribose- 5-phosphate isomerase; RpiA, ribose- 5- phosphate isomerase A; RpiB, ribose- 5-phosphate isomerase B; Ru5P, D-ribulose 5-phosphate; SpRpiB, Strep...

Ngày tải lên: 15/03/2014, 00:20

... changes on a putative membrane binding of < /b> the FYVE -type < /b> domain of < /b> TcrPDEC remains to be explored, but they render the TcrPDEC domain unlikely to bind to PtdIns(3)P. This prediction is confirmed by the ... arginine at the beginning of < /b> the second block is replaced by an alanine, the two adjacent histidine residues are replaced by serine and glutamine,...

Ngày tải lên: 19/02/2014, 07:20

... reactions in the immune system. The globular protein segment cor- responding to the carbohydrate recognition domain of < /b> C -type < /b> lectins (Ser84 to Lys199) mediates the binding of < /b> most monoclonal antibodies ... provided by the rapid GlcNAc binding test indicating that even the biological (carbohydrate binding) activity of < /b> solu- ble CD69 proteins was pre...

Ngày tải lên: 16/03/2014, 04:20

... hypothesis is based on the consideration that insertion of < /b> two bulky pyruvate groups at the end of < /b> the oligosaccharide chain blocks its elongation, by creating a structural hindrance to the action ... of < /b> LOSs has been reported to play a role in the interaction of < /b> the microorganism with the environment [12,13]. In this paper, the structural...

Ngày tải lên: 19/02/2014, 13:20

... (1fi3) -b- D -glucan-binding protein, which bind to (1fi3) -b- D -glucans, e.g. curdlan or laminarin. After binding of < /b> the carbohydrate to the receptor, the expression of < /b> the gene coding for the binding protein increases. ... Expression of < /b> the (1fi3) -b- D -glucan-binding protein and the fibrinogen-like protein occurred in cells on the sponge surface,...

Ngày tải lên: 16/03/2014, 16:20

... Russian Federation Gram-negative bacteria of < /b> the genus Proteus are com- mon in human and animal intestines but under favour- able conditions they cause infections of < /b> wounds, burns, skin, eyes, ears, ... lipopolysaccharides, inclu- ding those of < /b> 27 strains of < /b> P. vulgaris, 39 strains of < /b> P. mirabilis, 24 strains of < /b> P. penneri, one strain of < /b> P....

Ngày tải lên: 16/03/2014, 23:20

... three-dimensional structures < /b> of < /b> both peptides in membrane models. Further insight into the membrane-binding properties of < /b> the peptides and their depth of < /b> penetration into the lipid membrane has been obtained ... secondary structure that would enable them to insert into the membrane. Furthermore, the results demonstrate the feasibility of < /b> a nove...

Ngày tải lên: 17/03/2014, 11:20

... exhibiting stronger inhibition both as a function of < /b> time (Fig. 2) or as a function of < /b> concentration (Fig. 3). Under the conditions of < /b> our experiment, near-total inhibition by CIIIC could be observed, ... efficiency of < /b> protection of < /b> r 32 by CIII, because both are H B substrates. The relative binding affinity for r 32 –H B interaction and CIII–H B intera...

Ngày tải lên: 23/03/2014, 10:20

... 2005 FEBS interacting with carbohydrates [30]. The hydrophobic B- face of < /b> the sugar thus makes a number of < /b> nonpolar contacts with the indole ring of < /b> Trp373 (Fig. 3A). The interactions on the opposite ... differences between the enzymes in the relative contribution of < /b> intrinsic bind- ing energy to catalysis at subsites )3to)5. Another study reve...

Ngày tải lên: 23/03/2014, 13:20

... tions for the conduct of < /b> the interaction, and the sorts of < /b> capacities required of < /b> the interactants. In the de- sign Qf computer interactants, and in the introduction of < /b> technological intermediaries ... determine what type < /b> of < /b> person-person in- teraction we should consult. It is common to suppose that ordinary conversation is, or...

Ngày tải lên: 24/03/2014, 01:21