Báo cáo khoa học: The mouse Muc5b mucin gene is transcriptionally regulated by thyroid transcription factor-1 (TTF-1) and GATA-6 transcription factors pdf

... French governments works The mouse Muc5b mucin gene is transcriptionally regulated by thyroid transcription factor-1 (TTF-1) and GATA-6 transcription factors Nicolas Jonckheere 1,2 , Ame ´ lie ... Cancer 86, 162–168. 11 Escande F, Porchet N, Aubert JP & Buisine MP (2002) The mouse Muc5b mucin gene: cDNA and genomic Regulation of Muc5b muci...

Ngày tải lên: 15/03/2014, 00:20

... in the control of gene expression. As each step of the RNA metabolism is tightly regulated, the regulation of mRNA export, stability and transla- tion rate is essential for the control of the ... lacking this motif (DRS1) accumulated in the cytoplasm. By contrast, ASF ⁄ SF2 nucleo-cytoplasmic distribution is modified neither by the removal of the RS2 sub-domain,...

Ngày tải lên: 16/02/2014, 15:20

... heme d 1 biosynthesis genes and the co-production of both NirE and the other heme d 1 biosynthesis proteins, in high amounts ensures the efficient and highly concerted action of the proteins. In order ... proteins – NirE-His, Trx-S-NirE-His and S-NirE- His – and compared their catalytic activities. We observed that Trx-S-NirE-His and S-NirE-His showed similar activities. B...

Ngày tải lên: 18/02/2014, 06:20

... that the activity of the enzyme was inhibited by a low concentration of SDS (about 50% inhibition in the presence of 0.0025% SDS). On the other hand, an extensive degradation of SulA3±169 by the ... of incubation. On the other hand, no degradation of MBP was observed either in the presence or in the absence of ATP under the conditions used. These results indicated that...

Ngày tải lên: 21/02/2014, 03:20

... performed, and the monitor and the packing values were checked to determine the result from the candidates. We concluded that there is an (abc) 2 dimer in an asymmetric unit of the cell. The calculated ... dehydratase is a key enzyme for the dihydroxyacetone (DHA) pathway [23,26,27], and its genes are located in the DHA regulon [28,29]. On the other hand, diol dehy...

Ngày tải lên: 21/02/2014, 03:20

... with multiple transcription factors and are thought to bridge interactions between these transcription factors and SWI ⁄ SNF complexes, thereby allowing the recruit- ment of SWI ⁄ SNF to target genes ... factors (BAF). Among the later, the 60 kDa subunit BAF60 is found in most complexes; it can be represented by BAF60a, BAF60b or BAF60c, which are encoded by the sm...

Ngày tải lên: 06/03/2014, 09:22

... one in the center of the hexameric ring and another in a trilobed hole flanked by the hexamer spokes [72]. Although the mechanism of restriction is still unclear, reverse transcription of the viral ... structural changes in the CA-CTD, as is evident by the inability to form a C198-C218 disulfide bond, which is surprising consid- ering that 87 HAGPIA 92 is located i...

Ngày tải lên: 07/03/2014, 00:20

... important. One of these, the TRP sequence, includes the start of the C-terminal helix as well as the structured loop between the ATPase domain and the C-terminal helix and in the 3D structure is positioned ... helix). However, the majority of these proteins are likely to be other meiotic clade AAA ATPases and have the AAA domain helix and the C-terminal helix, bu...

Ngày tải lên: 07/03/2014, 05:20

... verification of the hypothe- sis is needed. However, this will not be difficult if the spFv system is utilized. In the present study, we demonstrated that library screening is indeed possible using the spFv ... sequences of all the mutants and the wild- type, sorted by this index, are summarized in Table 1. It is worth noting that while two clones with low affin- ity (1D5...

Ngày tải lên: 07/03/2014, 12:20

... lg each of the luciferase reporter construct and the b-galactosidase reporter control plasmid pSVb-gal (Promega). Transcription of the lacZ gene in this control vector is driven by the SV40 early ... leptin-induced activation of STAT factors was monitored by Western blot analysis with phospho-spe- cific antibodies and by reporter gene assays (Fig. 4). Consistent wit...

Ngày tải lên: 07/03/2014, 16:20