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Báo cáo khoa học: The association of viral proteins with host cell dynein components during virus infection pdf

Báo cáo khoa học: The association of viral proteins with host cell dynein components during virus infection pdf

Báo cáo khoa học: The association of viral proteins with host cell dynein components during virus infection pdf

... [118].ConclusionsIn the past few years, numerous studies of virus host interactions have revealed the role of the dynein motorand the integrity of microtubules in virus infection. The development of microscopy ... al. Viral proteins and host cell dynein components FEBS Journal 278 (2011) 2997–3011 ª 2011 The Authors Journal compilation ª 2011 FEBS 3011MINIREVIEW The association of viral proteins with host ... the fusion of the viral membrane with the plasma membrane of the cell. During passagethrough the cytosol, the viral RNA genome is reversetranscribed into DNA within a structure named the reverse...
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Báo cáo khoa học: Functional association of the AAA complex and the peroxisomal importomer potx

Báo cáo khoa học: Functional association of the AAA complex and the peroxisomal importomer potx

... complex in the cytosol, which associ-ates at the peroxisomal membrane with their membrane anchor Pex15pand the peroxisomal importomer. The interconnection of Pex15p with the components of the importomer ... determine whether the absence of Pex1p, Pex6p orPex15p has an influence on the association of the AAA complex with the importomer, we analyzed the composition of precipitates in the correspondingknock-out ... inwild-type cells, whereas only a fraction of the Pex15p-carrying importomer is associated with AAA peroxins.On deletion of components of the importomer, the amount of AAA proteins associated with...
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Báo cáo khoa học: Dynamic association of MLL1, H3K4 trimethylation with chromatin and Hox gene expression during the cell cycle ppt

Báo cáo khoa học: Dynamic association of MLL1, H3K4 trimethylation with chromatin and Hox gene expression during the cell cycle ppt

... at the beginning of the S phase(0 h), and these marks were attenuated for the rest of the cell cycle (10 and 20 h), correlating with the expression of the gene (Fig. 6C,D). The correlation of promoter ... distinctdynamics during cell cycle progression, we analyzed the expression profiles of MLL1, CGBP, Ash2 andRbbp5, together with cyclins E and B, as a function of the cell cycle. Western blot analysis of the ... affected, they are modulated at the promoters of specific genes over different phases of the cell cycle.Results and DiscussionDynamics of MLL1 and its interacting proteins during the cell cyclePrior...
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Báo cáo y học: "The association of meat intake and the risk of type 2 diabetes may be modified by body weight"

... study there was no information on associations of different types of meat and the risk of diabetes. Poultry consumption was associated with a moderate decrease in risk of type 2 DM in the NHS ... was the major component of red meat intake (90%). Only beef and hamburgers but not pork was associated with the risk of type 2 DM in the NHS II [6]. In our population the cut off points of ... two of the main components of the ‘Western diet’, while poultry has been reported as part of the ‘prudent diet’ in most studies [5;16;26], but not all [17]. It remains unclear whether the...
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Tài liệu Báo cáo khoa học: The occurrence of hemocyanin in Hexapoda docx

Tài liệu Báo cáo khoa học: The occurrence of hemocyanin in Hexapoda docx

... assembled with genedoc 2.7 [41]. The tools provided with the ExPASy Molecular BiologyServer of the Swiss Institute of Bioinformatics (http://www.expasy.org) were used for the analyses of DNA andamino ... On the tracheal system of Collembo-la, with special reference to that of Sminthurus viridis,Lubb. Q J Microsc Sci 71, 15–30.39 Williams CB (1913) A summary of the present knowl-edge of the ... possible ‘intermediate’. The evolution of hemocyanin subunits follows the widely accepted phylogeny of the Hexapoda and provides strong evidencefor the monophyly of the Polyneoptera (Plecoptera,...
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Tài liệu Báo cáo khoa học: The effect of small molecules in modulating the chaperone activity of aB-crystallin against ordered and disordered protein aggregation pdf

Tài liệu Báo cáo khoa học: The effect of small molecules in modulating the chaperone activity of aB-crystallin against ordered and disordered protein aggregation pdf

... aB-crystallin (i.e. the effect of the additive on the aggregation of the target protein is inde-pendent and different from that of the chaperone). The standard errors associated with this theoretical ... calculated from the standard errorsassociated with the means of the measured values (i.e. bycalculating the square root of the sum of the associatedindividual errors squared). The maximum percentage ... concentrations of Arg-HClin the absence of the chaperone precluded analysis of the effect of this concentration on the protectiveability of aB-crystallin.Reduction-induced aggregation of the insulin...
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Tài liệu Báo cáo khoa học: The sequentiallity of nucleosomes in the 30 nm chromatin fibre pptx

Tài liệu Báo cáo khoa học: The sequentiallity of nucleosomes in the 30 nm chromatin fibre pptx

... in which the presence of linker his-tone is questionable. Furthermore, the presence of alloligomers, with dimers up to the half the size of the original samples after digestion of the linkers, ... Indeed, there is evidence that the tails of thesehistones follow the path of the linker DNA [5]. Theyare crosslinked first to each other first and subse-quently to the core histones [19]. The even ... consists of the entire chroma-tin of the nucleated avian erythrocytes and comprisesapproximately 85% of the chromatin in other cell types [5]. The structure of chicken erythrocyte chromatin isthe...
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Tài liệu Báo cáo khoa học: The stereochemistry of benzo[a]pyrene-2¢-deoxyguanosine adducts affects DNA methylation by SssI and HhaI DNA methyltransferases pptx

Tài liệu Báo cáo khoa học: The stereochemistry of benzo[a]pyrene-2¢-deoxyguanosine adducts affects DNA methylation by SssI and HhaI DNA methyltransferases pptx

... accordance with this, the depend-ence of the fluorescence of the (+)-trans adduct on itsposition relative to the target dC was revealed in the case of the formation of the complexes of M.SssI with ... associated with the intercalativeconformation of the (+)-cis adduct and the minor-groove conformation of the (+)-trans adduct, the lat-ter interfering with interactions of the catalytic loops of the ... FEBSresidues within the catalytic domain of the M.HhaI with the DNA minor groove play an important role in the methylation reaction. The contacts of the M.HhaIsmall domain with the DNA major...
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Tài liệu Báo cáo khoa học: The localization of FGFR3 mutations causing thanatophoric dysplasia type I differentially affects phosphorylation, processing and ubiquitylation of the receptor pptx

Tài liệu Báo cáo khoa học: The localization of FGFR3 mutations causing thanatophoric dysplasia type I differentially affects phosphorylation, processing and ubiquitylation of the receptor pptx

... occurs within the Golgi system was prevented by blocking transport from the ER to the Golgi. BFA had no effect on the relativelack of the 130 kDa isoform of the K650M mutant.Endo H digestion of the ... to a role for components of the ER–Golgi vesicle transport. Through the use of mark-ers for the ER (PDI) and the Golgi apparatus(GM130, p230), the phosphorylated isoforms of the K650M mutant ... colocalization of the two proteins in cells transfected with the Y373C,R248C and X807R mutants (Fig. 2Eh,j and notshown). The K650M mutant was much morecolocalized with PDI than the other mutants...
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Tài liệu Báo cáo khoa học: The role of electrostatic interactions in the antitumor activity of dimeric RNases docx

Tài liệu Báo cáo khoa học: The role of electrostatic interactions in the antitumor activity of dimeric RNases docx

... perpendicular to the center of the membrane(Fig. 4);(b) the major axis of the dimeric RNase was made coinci-dent with the z axis of the system, hence orthogonal to the membrane plane (Fig. 4);(c) the ... Nter are the C-terminal and N-terminal structural regions,respectively, of the two A and B monomers of the dimeric RNase. The black circle between the monomers indicates the mass center of the dimer.E. ... 3687–3697 ª 2006 The Authors Journal compilation ª 2006 FEBS 3691RNases oriented with the negative end of the dipolestoward the bottom, and the positive one toward the top of the figure. Figure...
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