Báo cáo khoa học: Molecular basis of toxicity of Clostridium perfringens epsilon toxin ppt

... of neutralizing antibodies against Clostridium perfringens epsilon- toxin. Infect Immun 75, 1785–1793. M. Bokori-Brown et al. Molecular basis of toxicity of C. perfringens e toxin FEBS Journal 278 (2011) ... Assessment of aspects of the toxicity of Clostridium perfringens epsilon- toxin using the MDCK cell line. Hum Exp Toxicol 15, 904–908. 37 Lindsay CD,...

Ngày tải lên: 14/03/2014, 22:20

... molecular mode of action of glypho- sate and the molecular basis for glyphosate resistance. Structure and function of EPSPS EPSPS catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate ... however, was devoid of substrate or inhibitor, and consequently did not reveal the nature of the active site or the mode of action of glyphosate. A dec- ade later, t...

Ngày tải lên: 14/02/2014, 14:20

... 1023–1034. N. Numa et al. Molecular basis of perinatal form of hypophosphatasia FEBS Journal 275 (2008) 2727–2737 ª 2008 The Authors Journal compilation ª 2008 FEBS 2737 Molecular basis of perinatal hypophosphatasia ... synthesis of an excess amount of TNSALP (Fig. 1C, lanes 4–6, see the top of gel). In the present experiment, TNSALPs were expressed Molecular basis of...

Ngày tải lên: 07/03/2014, 05:20

... 674–676. Molecular basis of cytokine signalling W. Sebald et al. 118 FEBS Journal 277 (2010) 106–118 ª 2009 The Authors Journal compilation ª 2009 FEBS THE THEODOR BU ¨ CHER LECTURE Molecular basis of ... structure of the extracellular ligand-binding domain of a number of these receptor complexes has now been elucidated, providing the molecular basis for understanding th...

Ngày tải lên: 15/03/2014, 09:20

... amebal PGKs. 3D predicted model of EhPGK Predicted 3D structures of the EhPGK were obtained by means of modeller software (see Fig. S1 for details on these models) and molecular operating environ- ment ... sequences analyzed. The analysis of the predicted structure suggested that the presence of the shorter lateral chain of Val311 instead of Leu allows for the movement of Ty...

Ngày tải lên: 16/03/2014, 01:20

... the molecular basis of the specificities of reactivating fac- tors in the reactivation of inactivated holoenzymes and the activation of inactive enzyme–cobalamin com- plexes, the possibility of ... mM MgCl 2 , in a total volume of 25 lL. The amount of propionaldehyde formed was determined as described in the text. The extents of reactivation of diol dehydratase by DDR and...

Ngày tải lên: 16/03/2014, 05:20

... func- tion of the normal cellular isoform of prion protein is not exactly known, the impact of gain of toxic function or loss of function, or a combination of both, in prion pathology is still ... is used by us here for induction of neuro- degeneration, and PrP Sc is used synonymously for the pathological form of PrP. Toxicity of transmembrane isoforms of PrP The evidenc...

Ngày tải lên: 30/03/2014, 09:20

... Irene T. Weber 1,2 1 Department of Chemistry, Molecular Basis of Disease, Georgia State University, Atlanta, GA, USA 2 Department of Biology, Molecular Basis of Disease, Georgia State University, ... Atlanta, GA, USA 3 Department of Biochemistry and Molecular Biology, Faculty of Medicine, University of Debrecen, Hungary 4 Department of Computer Science, Molecular...

Ngày tải lên: 30/03/2014, 20:20

... Approximately 0.4 mg of protein was treated with 10 mU of glycosidase F (Sigma-Aldrich Inc.) at 37 °C for 16 h. For crosslinking of proteins, slices of cotyledons were homogenized with 20 strokes of a Dounce ... S1. Comparison of intron–exon structures of GmPDIL-3a, GmPDIL-3b and orthologs of other plants. Fig. S2. Multiple amino acid sequence alignment of GmPDIL-3a, GmPDIL-...

Ngày tải lên: 18/02/2014, 11:20

... transfer of the c-phos- phate group from ATP to AMP, releasing two molecules of ADP [1]. Different isoenzymic forms of AK are involved in maintenance of constant intracellular levels of adenine nucleotides, ... Valencia, Spain). The analysis of the nucleotide sequence revealed the presence of a 690-bp long ORF that encoded a protein of 230 amino acids, with an estimated molec...

Ngày tải lên: 21/02/2014, 00:20