Báo cáo khoa học: Actin as target for modification by bacterial protein toxins docx

... al. Actin as target for toxin modification FEBS Journal 278 (2011) 4526–4543 ª 2011 The Authors Journal compilation ª 2011 FEBS 4543 REVIEW ARTICLE Actin as target for modification by bacterial protein ... interaction with actin molecules is the basis for the rearrangement of the actin cytoskeleton by bacterial effectors like Salmonella invasion protein A (...

Ngày tải lên: 14/03/2014, 22:20

... ammonia-lyase [44] and ribonucleotide reductase [29] and a weak competitive inhibitor for methylmalonyl-CoA mutase [44]. 2¢-De- oxyAdoCbl is 31%, 17%, and 5–13% as active as Ado- Cbl for diol dehydratase ... 400 m )1 Æcm )1 for diol dehydratase and ethanolamine ammonia-lyase, respectively. Based on the predicted molecular masses, e 1%,280 was calcu- lated to be 5.81 and 6.21 for t...

Ngày tải lên: 07/03/2014, 21:20

... clustering tasks, including seven 2- way clustering tasks, two 4-way clustering task, one 5-way clustering task and one 8-way cluster- ing task. The detailed descriptions for these clus- tering tasks ... training text as well as the translated target text together, in terms of the information theory. We allowed all the information to be put through a ‘bottleneck’ and be represented b...

Ngày tải lên: 08/03/2014, 00:20

... determiner formulas. In a given context, the evaluation of a logical formula is determined by the specifications of the variables con- tained in that formula. There are several well known methods for ... logical rules for formula reduction are rigorous and machin- able. A computer program that reduces formulas given in disjunctive canonical forms to more economical normal forms...

Ngày tải lên: 16/03/2014, 19:20

... focus for SMT to date has been on translation into English, for which the models work relatively well, especially for source languages that are structurally similar to English. There has been less ... sequence model based on part-of-speech, which potentially can improve word order and agreement. I take ad- vantage of available tools, such as the Moses toolkit (Koehn et al., 2007) for...

Ngày tải lên: 23/03/2014, 16:20

... increases the K m of APC for cleavage of FVa at Arg506 5.5-fold and at the same time decreases the k cat 2.6-fold, thus acting as a mixed-type inhibitor of APC. As this analysis was performed ... homology model based on ceruloplasmin, formed by Asp659-Asp660- Asp661-Glu662-Asp663 may also play a role during the docking of APC on to the FVa Arg506 site. In contrast, the segment contain...

Ngày tải lên: 19/02/2014, 13:20

... appropriate. By defining broad enough classes of entities for which these questions might be asked (e.g. people, places, organizations and things, or major subclasses of these), we can for each ... manually derived for our prototype system, they are fairly general for the human life-cycle and can be easily reused for other, similar questions, or for more complex dossiers,...

Ngày tải lên: 31/03/2014, 03:20

... Sessions, pages 37–40, Ann Arbor, June 2005. c 2005 Association for Computational Linguistics Learning Source -Target Surface Patterns for Web-based Terminology Translation Jian-Cheng Wu Department ... outperforms the state-of-the-art online machine translation systems. 1 Introduction Translation of terms has long been recognized as the bottleneck of translation by transla...

Ngày tải lên: 20/02/2014, 15:20

... be defined. For example, the lexical entry for frog would be FROG:<>==NOUN, where the noun-specific information is inherited from NOUN. This third approach forms the base for our current ... INFORMATION The formalism of PATR offers two possible means of representing lexical informa- tion. First of all, the information can be encod- ed in feature structures directly. Exce...

Ngày tải lên: 18/03/2014, 02:20

... in the yeast. In contrast, activation of certain other clients (glucocorticoid receptor; extracellular signal-regu- lated kinase-5 mitogen-activated protein kinase) was less affected by the human ... kinase; GR, glucocorticoid receptor; HSF, heat shock transcription factor; Hsp90, heat shock protein 90; MAP kinase, mitogen-activated protein kinase; v-src, v-src tyrosine kinase; Y2H, y...

Ngày tải lên: 23/03/2014, 07:20