... the wedge hypo-thesis of Tytler et al. [48], it may be that insertion of the inverted wedge shape formed by the AP1 a-helixinto membranes of E. coli leads to the formation of nonbilayer structures ... of 100 °. Theresultant of this summation, the hydrophobic moment, pro-vides a measure of a-helix amphiphilicity. The analysis of the present study used a moving window of 11 residues,and for ... Science, University of Central Lancashire, Preston, UK2 School of Natural Resources, University of Central Lancashire, Preston, UK3 Forschungszentrum Borstel, Leibniz-Center for Medicine and Biosciences,...