... Localizations of serine racemase protein and mRNA in the brain. (A) Staining for serine racemase in the cerebral cortex (Ctx) of a P7rat (layers IV–VI). (B) Staining of neurons in the stratum pyramidale ... that serine racemase, the d-serine biosynthetic enzyme, iswidely expressed in neurons of the brain, suggesting that d-serine also hasa neuronal origin. We now review these findings, focusing on ... nuclei of the hindbrain[38,39,66] and in ganglion cells of the retina [67].Table 1. Some transmitter-like properties of brain D-serine. ASCT, alanine, serine, cysteine and thrionine transporter.D-Serine...