Báo cáo Y học: The proximal cis-acting elements Sp1, Sp3 and E2F regulate mouse mer gene transcription in Sertoli cells potx
... apart from Sp1, Sp3 is also present in the protein complexes bound to the Sp1 cis-acting motifs in the Mer promoter by the Supershift assay using the Sp1 and Sp3 antibodies. Interestingly, Sp3 did ... unknown transcriptional factor play a critical role in regulating the proximal promoter activi- ties of Mer. Keywords :E2F; Mer gene; receptor tyrosine kin...
Ngày tải lên: 08/03/2014, 23:20
... W. succinogenes [7,8,15]. The cytochrome b subunits of the two enzymes ( HydC and FdhC) which carry the sites of quinone reduction are similar. Their four histidine residues c oordinating the two ... ron and sul®de, and menaqui- none. Heme, ¯avin and other heavy metals were absent. The enzyme catalyzed the reduction of polysul®de by BH 4 ± [reaction (c)] and the oxidat...
Ngày tải lên: 24/03/2014, 03:21
... ribozyme DiGIR1, located within the twin- ribozyme intron Dir.S956-1. The RNA retains the majority of Dir.S956-1 including the homing endonuclease gene and a small spliceosomal intron, the internal ... cellsharvestedearlyandlateinatime course (corresponding to time points 1 and 6 in Fig. 2). These RNAs were analysed by Northern blotting and RNaseH cleavage. In the Nort...
Ngày tải lên: 23/03/2014, 21:20
Báo cáo Y học: The sodium pump Its molecular properties and mechanics of ion transport potx
... by which the tyrosine residues might in uence interactions of theenzymewithK + are not yet understood. SPECIFIC INHIBITORS Possibly due to its key function in cellular physiology and indeed the ... a guide in their search for gathering specific information concerning the structure, function, and enzymology of this enzyme. Keywords: ATPase; P-type; ouabain; palytoxin; ion transpo...
Ngày tải lên: 24/03/2014, 00:21
Báo cáo y học: No associations of Helicobacter pylori infection and gastric atrophy with plasma total homocysteine in Japanes
... pylori infection and gas- tric atrophy according to the genotypes of MTHFR and TS in any subgroups defined by the genotypes (Table 2). Table 3 shows the ORs and 95% CIs of hyper- homocysteinemia ... Thymidylate synthase (TS) gene encodes the en- zyme that catalyzes the conversion of deoxyuridylate to thymidylate. The enzyme expression is reportedly affected by a 28b...
Ngày tải lên: 31/10/2012, 14:34
Báo cáo Y học: Overexpression of a recombinant wild-type and His-tagged Bacillus subtilis glycine oxidase in Escherichia coli pptx
... activity o n s arcosine and N-ethylglycine. In contrast, an appreciable activity on glycine, glycine-ester a nd D -pipecolic acid was only observed using GO. Interestingly, D -proline i s t he only ... residues of the chimeric protein) at the N-terminus, which clearly does not impair either the enzymatic activity or the coenzyme binding. The purification of the His-tagged chime...
Ngày tải lên: 08/03/2014, 16:20
Báo cáo y học: "The Systemic Inflammatory Response Syndrome (SIRS) in acutely hospitalised medical patients: a cohort study"
... identified by two or more symptoms including fever or hypothermia, tachycardia, tachypnoea and change in blood leucocyte count. The relationship between SIRS symptoms and morbidity and mortality in medical ... moderately associated with infection and strongly related to 28-day mortality. Background Sepsis is a systemic inflammatory response to a confirmed or suspected infection....
Ngày tải lên: 25/10/2012, 09:56
Báo cáo y học: "The epidemiology of medical emergency contacts outside hospitals in Norway - a prospective population based study"
... emergency care, both in the primary and the secondary health care sys- tem, namely an increasingly older population and there- fore more pressure on the emergency systems both inside and outside ... response level based on the Index [1]. The Index is based on ideas from the Criteria Based Dispatch system in the US [15], and was first published in 1994. Clinical sym...
Ngày tải lên: 25/10/2012, 09:56
Báo cáo y học: "The evolving story of medical emergency teams in quality improvement"
... distinct career pathway. Involving such physicians in medical emergency teams will likely facilitate the dual roles of these as a clinical outreach arm of the intensive care unit and in identifying problems ... the standardized MET form on each patient and a weekly 1-hour Commentary The evolving story of medical emergency teams in quality improvement André Carlos Kajdacsy-Ba...
Ngày tải lên: 25/10/2012, 10:06
Báo cáo y học: "The epidemiology of intensive care unit-acquired hyponatraemia and hypernatraemia in medical-surgical intensive care unit"
... revised the manuscript. HTS and FK had full access to all the study data and assume responsibility for the integrity of the data and the accuracy of the analysis. References 1. Himmelstein DU, ... were included in the study cohort if their ICU stay was longer than one day in duration and they were documented to have exclusively 'normal' serum sodium level(s...
Ngày tải lên: 25/10/2012, 10:31