Báo cáo Y học: Molecular mechanisms underlying SHP-1 gene expression potx
Báo cáo y học: "Transporter Molecules influence the Gene Expression in HeLa Cells"
... employed the
Fmoc (9-fluorenyl-methyloxycarbonyl) methodology
[37, 38] in a fully automated multiple synthesizer
(Syro II from Multi Syntech Germany). As coupling
agent 2-(1H-Benzotriazole-1-yl)-1,1,3,3-tetramethylu-
roniumhexafluoro-phosphate ... impact on the gene expression
patterns, when analyzing the efficacy and the genetic
consequences of targeted gene therapy in vitro (and...
Báo cáo y học: "Pathogenic Mechanisms Shared between Psoriasis and Cardiovascular Diseas"
... Th1-type cytokine
production in coronary atherosclerosis [32].
Finally, IL-17 which is produced by activated
CD4+ T-cells acts synergistically to elicit further pro-
duction of pro-inflammatory ... limited by the
potential for adverse effects such as hypertension,
dyslipidemia, hyperhomocysteinemia, and renal and
hepatic toxicity. Thus preventive measures may be
required during therapy...
Báo cáo y học: "Molecular Virology of Hepatitis C Virus (HCV): 2006 Update"
... pseudotypes displaying functional HCV glycoproteins. These pseudotypes turned out to provide a robust
model system for the study of viral entry [10, 11]. HCV pseudoparticle infectivity is pH-dependent ... replaced by the sequence encoding the
neomycin phosphotransferase gene resulting in G418 resistance. Expression of the nonstructural proteins is directed by
a heterologous encephalomy...
Tài liệu Báo cáo Y học: Molecular modeling of the dimeric structure of human lipoprotein lipase and functional studies of the carboxyl-terminal domain docx
... endothelial lipase [1,2]. The
primary function of LPL is triglyceride hydrolysis in
triglyceride-rich lipoproteins, such as chylomicron and very
low density lipoprotein (VLDL) particles, which ... domain
Yoko Kobayashi, Toshiaki Nakajima and Ituro Inoue
Division of Genetic Diagnosis, Institute of Medical Science, The University of Tokyo, Tokyo, Japan
Lipoprotein lipase (LPL) plays a key role...
Báo cáo khoa học: Molecular mechanisms of the phospho-dependent prolyl cis ⁄ trans isomerase Pin1 docx
... phosphate, acetyl
or methyl group), leading to a product that is distin-
guishable by mass spectrometry or immunochemistry
from the incoming molecular entity. The modification
imposed by prolyl cis ⁄ ... activity
by the immunophilin FKBP52. Immunity 12, 129–140.
80 Shen ZJ, Esnault S & Malter JS (2005) The peptidyl–
prolyl isomerase Pin1 regulates the stability of granulo-
cyte–macrophag...
Báo cáo Y học: Molecular cloning, bacterial expression and properties of Rab31 and Rab32 docx
... coupled
to keyhole limpet haemocyanin via their endogenous
(Rab31) or added (Rab32, Rab11A) cysteine residues, using
4-(N-maleimidomethyl) cyclohexane-1-carboxylate. Rabbits
were immunized by intradermal ... W.A. (1996)
Molecular cloning of two novel rab genes from human melano-
cytes. Gene 174, 129±134.
26. Terryn, N., Anuntalabhochai, S., Van Montagu, M. & Inze
Â
,D.
(1992) Analys i...
Báo cáo y học: "Effect of antibodies on the expression of Plasmodium falciparum circumsporozoite protein gene"
... as
described by Trager and Jensen [8]. Cultures were
synchronised by two rounds of sedimentation using
gelatine. Briefly, cultures of approximately 5% parasitised
erythrocytes (PE) were centrifuged, ... was performed with the GeneAmp
®
5700 system
(PE Applied Biosystems) using the following cycle profile:
1 cycle at 48°C for 30 min, 1 cycle
at 95°C for 10 min, 40
cycles at 95°C for...
Tài liệu Báo cáo Y học: Purification, characterization, cloning, and expression of the chicken liver ecto-ATP-diphosphohydrolase pot
... ATPase
activity at either pH 7.4 or pH 6.4 (Fig. 3). At pH 7.4,
5m
M
azide inhibited ADP hydrolysis by 70% whereas
ATP hydrolysis was inhibited by only 10%. Inhibition of
ADP and ATP hydrolysis by azide ... ecto-ATPDase were affected differently by
pH. Figure 2 shows that the pH–activity curves of ATP and
ADP hydrolysis do not coincide. While maximal ATP
hydrolysis activity was obtained in...
Tài liệu Báo cáo Y học: Analyses of the CYP11B gene family in the guinea pig suggest the existence of a primordial CYP11B gene with aldosterone synthase activity docx
... 11b(OH)-androstendi-
one were synthesized by CYP11B2 in comparison with
CYP11B1 (Fig. 4C). It is noteworthy, that CYP11B2
displayed a higher enzymatic activity than CYP11B1 based
on 11b-hydroxylase activity. These ... by means of
an 11b-hydroxylation and an 18-hydroxylation/oxidation of
11-deoxycorticosterone. Thus, the proteins of the CYP11B
subfamily catalysing the last biosynthetic steps a...
Báo cáo Y học: Structural analysis of Francisella tularensis lipopolysaccharide potx
... carrying four acyl residues. GlcN
residue A had unsubstituted hydroxyl group at C-1, and was
mostly present in an a-pyranose form. Acyl
1
,acyl
2
and acyl
3
residues had hydroxy or acyloxy groups ... 2-N-(3-O-
acyl
4
-acyl
2
)-b-GlcN-(1–6)-2-N-acyl
1
)3-O-acyl
3
-GlcN where
acyl
1
,acyl
2
and acyl
3
are 3-hydroxyhexadecanoic or 3-hy-
droxyoctadecanoic acids, acyl
4
is tetradecanoic or (minor)...