Báo cáo Y học: Structure, mechanism and function of prenyltransferases docx

... undecaprenyl pyrophosphate synthase; DDPPS, dehydrodolichyl pyrophosphate synthase; PPPS, polyprenyl pyrophosphate synthase; GPPS, geranyl pyrophosphate synthase; FPPS, farnesyl pyrophosphate synthase; ... each of the other 19 amino-acid residues showed that Y8 1A, Y8 1G and Y8 1S are capable of making hexaprenyl pyrophosphate (C 30 ) [59]. The final products of Y8 1C, Y8 1H, Y8...

Ngày tải lên: 08/03/2014, 22:20

... studies analysing a small number of polymorphisms (n = 1-3) should be evaluated extremely cautiously, because a very large number of such studies are inconclusive and statistically under-powered. ... trials: authors’ name, year of publication, country of origin, type of cancer, sample size, number of polymorphisms tested and results of the study. Studies were divided int...

Ngày tải lên: 25/10/2012, 10:51

... prevalence of hyperopia and myopia. As age increased, the prevalence of hyperopia signif- icantly decreased and the prevalence of myopia in - creased. Based on the definitions of hyperopia (≥+2.00 ... prevalence of hyperopia markedly decreased, and that of myopia significantly increased. The prevalence of hyperopia was 48.12% (≥ +1.50 D SE) and 9.21% (≥ +2.00 D SE) a...

Ngày tải lên: 25/10/2012, 11:40

... Availability for the duration of the entire study period Exclusion History of underlying inflammatory arthropathy or severe rheumatoid arthritis Hyperuricaemia (>440 μmol/l) and/ or past history of ... Golakoti T, Sarma KV, Dey D, Raychaudhuri SP. A double blind, randomized, placebo controlled study of the efficacy and safety of 5-Loxin ® for treatment of osteoarthrit...

Ngày tải lên: 25/10/2012, 11:40

... at the Peptide Synthesis and Analysis Laboratory of the Department of Medical Biochemistry and Microbio- logy, Uppsala University. The SP6 primer 5¢-ATT TAG GTG ACA CTA TAG-3¢ and the three oligonucleotide PCR-primers ... embryonic kidney cell cDNA- library followed by expression and purification, yielded a protein with a molecular mass of 13 700 Da, and an EDTA-insensitive pho...

Ngày tải lên: 21/02/2014, 01:21

... ortholog of HRPC2 (91% amino acid identity). Shinmyo et al. [64] have studied the promoter activity and wound-induction of HRPC and -E types, and of AtPCa and AtPEa. Most remarkably, C2, and only C2, responded ... Differential activity and structure of highly similar peroxidases. Spectroscopic, crystallographic, and enzymatic analyses of lignifying Arabidopsis thaliana...

Ngày tải lên: 21/02/2014, 01:21

... two possible mechanisms: a de novo synthesis, catalysed by phosphatidylinositol synthase (EC 2.7.8.11), also known as CDP-diacylglycerol (DAG)/myo- inositol 3-phosphatidyltransferase, and an exchange ... phosphatidylinositol; PtdOH, phosphatidic acid; CDP-DAG, CDP-diacylglycerol; CMP, cytidine monophosphate; CTP, cytidine triphosphate. Enzymes: phosphatidylinositol synthase or CDP-diacylgly...

Ngày tải lên: 22/02/2014, 04:20

... com- plexes may represent true physiologically relevant interactions in stationarily grown cells. Identification of proteins X (GatY) and Y (UP12) In order to identify polypeptides X and Y, we repeated ... of ybdQ deletion on cell growth at 37 °C and on sensitivity towards CCCP exposure. (A) Growth curves of wild-type and D ybdQ cells in Luria–Bertani broth. Single colonies o...

Ngày tải lên: 22/02/2014, 07:20

... compilation ª 2009 FEBS of Spa ¨ tzle-C108 (Fig. 8A). Analysis of tryptic peptides from these bands by MS ⁄ MS and mascot software identified them as attacin-1, lysozyme, and cecropin- A ⁄ B (Table ... larvae) derived from cleavage of proSpa ¨ tzle-1A by HP8 Xa , and repurified by nickel affinity chromatography, as described above. Twenty hours later, fat body and hemolymph samples...

Ngày tải lên: 06/03/2014, 09:22

... the total loss of this activity when assayed in the usual way, i.e. after addition of H 2 , a catalytic amount of NADH and the subsequent addition of BV. Restoration of this activity (to 88%) also required ... of benzyl viologen by H 2 was not dependent on the presence of FMN-a. Enzyme devoid of FMN-a could not be activated by NADH. As NADH-dehydrogenase activity was not dep...

Ngày tải lên: 07/03/2014, 15:20