Báo cáo Y học: Transient activation of the c-Jun N-terminal kinase (JNK) activity by ligation of the tetraspan CD53 antigen in different cell types pptx

... JNK activation by CD53 ligation (Eur. J. Biochem. 269) 1021 Transient activation of the c-Jun N-terminal kinase (JNK) activity by ligation of the tetraspan CD53 antigen in different cell types Mo ´ nica ... transduction by determining the effect of its ligation on the c-Jun N-terminal kinase (JNK) in different cell types...

Ngày tải lên: 08/03/2014, 22:20

... aeruginosa at baseline reported in other studies [4-6] because of activity against key pathogens. Consideration of the influence of appro- priateness of empiric therapy against subsequently identi- fied ... hazards was tested in each case by examining the effect -by- time interaction effect jointly for all covariates, and individually for each covari- ate entered into the...

Ngày tải lên: 25/10/2012, 10:02

... were also obtained from the individual airlines. rpk is a measure of the volume of passengers carried by an airline; it is the sum of the products obtained by multiplying the number of revenue passengers ... that by the year 2030, half of all aircraft passengers will be over 50 years of age [1]. In addition to the continuous increase in the average age o...

Ngày tải lên: 25/10/2012, 10:31

... supplements. Theoretically, they may promote weight loss by interfering with the breakdown of complex carbohydrates thereby reducing, or at least slowing, the digestive availability of carbo- hydrate-derived ... Examining intragroup analysis of the Control group by the paired t test, the following averages ± SEM were found at the beginning and end of the study r...

Ngày tải lên: 31/10/2012, 15:12

... The Authors Journal compilation ª 2009 FEBS DNA synthesis evaluated by [ 3 H]thymidine incorporation Cell proliferation was evaluated as the rate of DNA synthe- sis by [ 3 H]methylthymidine incorporation ... replication. Results BetA-induced selective cytotoxicity in HBV-infected hepatocytes We first examined the cytotoxicity of BetA in wild- type (WT) and HBV-infected hepa...

Ngày tải lên: 16/03/2014, 01:20

... 2002 converge in their activity on the phosphorylation of E lk-1, including the c ascade leading to the activation of stress activated protein kinases (JNK/SAPK), the ras-activated factor/extracellularly ... 2002 of c-Jun (S73) was only marginal. By using a pan -c-Jun antibody, which recognizes c-Jun independently of its phosphorylation status, a partial phosphory...

Ngày tải lên: 17/03/2014, 17:20

... phosphorylation of the C-terminus of R* and binding by arrestin. Phosphorylation somewhat decreases the ability of R* to signal transducin. Rapid shut- off of R* signalling is then accomplished by binding ... changes in the proteolytic digestion pattern that result from phosphopeptide binding [7] or by heparin binding [11], and changes in cysteine reactivity due to pho...

Ngày tải lên: 22/02/2014, 07:20

... to increase by 2.5– to threefold in the presence of TPA. Thus the increase in the level of PS1 mRNA observed by Northern blotting of total cellular RNA results from an increase in the rate of initiation ... increases the rate of transcription initiation of the PS1 gene in SK-N-SH cells To determine whether the increase in the level of PS1 mRNA resul...

Ngày tải lên: 08/03/2014, 09:20

... built a homology model of human PXR in order to identify residues that were likely to be involved in ligand binding. Since the initiation of this study the crystal structure of the human receptor ... hydrophilic side chain has been replaced by a hydrophobic one in the core of the ligand binding pocket. The Q285I mutant also shows decreased propensity for activatio...

Ngày tải lên: 08/03/2014, 16:20

... explained by the association of these proteins in a complex. As in the preceding fractionations, eluted proteins were analyzed by SDS/PAGE, followed by Coomassie blue staining. At this stage of the ... S100A8/A9, accompanied by a majority of p67phox, p47phox and Rac. Analysis of the protein distribution in the two HTP pools by SDS/PAGE followed by Coomassie...

Ngày tải lên: 18/03/2014, 01:20