... expansion of the model is not properly managed, the result of the evaluation of such a formula can be wrong (i.e. inconsistent with the contents of the model). Two mechanisms for maintaining ... This forces the model to expand to contain the property of talking. The addition of this new property expands the domain of the set of properties denoted by "John",...
Ngày tải lên: 21/02/2014, 20:20
... Proceedings of the 45th Annual Meeting of the Association of Computational Linguistics, pages 360–367, Prague, Czech Republic, June 2007. c 2007 Association for Computational Linguistics The Utility of ... Consequently, in this paper we propose using a graphical representation of the discourse structure as a way of improving the performance of com- plex-domain dialogue s...
Ngày tải lên: 20/02/2014, 12:20
Tài liệu Báo cáo khoa học: The occurrence of hemocyanin in Hexapoda docx
... provided with the ExPASy Molecular Biology Server of the Swiss Institute of Bioinformatics (http:// www.expasy.org) were used for the analyses of DNA and amino acid sequences. Signal peptides ... supported by a grant of the Deutsche Forschungsgemeinschaft (Bu956 ⁄ 9). We thank J. Korb, K. Meusemann, M. Marx, B. Misof and B. Walz for providing hexapod species and M. Machola for h...
Ngày tải lên: 18/02/2014, 08:20
Tài liệu Báo cáo khoa học: The effect of small molecules in modulating the chaperone activity of aB-crystallin against ordered and disordered protein aggregation pdf
... amount of precipitation in the presence of high concentrations of Arg-HCl in the absence of the chaperone precluded analysis of the effect of this concentration on the protective ability of aB-crystallin. Reduction-induced ... responsible for inclu- sion body formation, and therefore the ability to pre- vent it would be of enormous benefit in recombinant protein production, a...
Ngày tải lên: 18/02/2014, 16:20
Tài liệu Báo cáo khoa học: The sequentiallity of nucleosomes in the 30 nm chromatin fibre pptx
... R (1980) Stability and reversibility of higher ordered struc- ture of interphase chromatin: continuity of deoxyribo- nucleic acid is not required for maintenance of folded structure. Biochemistry ... helical arrays: one for repeat lengths below 210 bp with a diameter of 33 nm and another for repeat lengths above 210 bp with a diameter of 45 nm and with the flat surfaces of...
Ngày tải lên: 18/02/2014, 18:20
Tài liệu Báo cáo khoa học: The stereochemistry of benzo[a]pyrene-2¢-deoxyguanosine adducts affects DNA methylation by SssI and HhaI DNA methyltransferases pptx
... fluorescence intensities at 384 nm were calculated. Determination of the amounts of the active form of M.SssI and M.HhaI The amount of the active form of M.SssI (338 ± 22 nm) and M.HhaI (120 ± 10 lm) was ... epoxide of B[a]P is not formed in eukaryotic cells [8], it is often used in structure–function studies of B[a]P-N 2 -dG adducts because of the different conformational char...
Ngày tải lên: 19/02/2014, 00:20
Tài liệu Báo cáo khoa học: The localization of FGFR3 mutations causing thanatophoric dysplasia type I differentially affects phosphorylation, processing and ubiquitylation of the receptor pptx
... pointed to a role for components of the ER–Golgi vesicle transport. Through the use of mark- ers for the ER (PDI) and the Golgi apparatus (GM130, p230), the phosphorylated isoforms of the K650M mutant ... Because of the lower affinity of the antibody, the amount of total protein used for immunoprecipitation of the X807R mutant was three times that used for wild-type and o...
Ngày tải lên: 19/02/2014, 00:20
Tài liệu Báo cáo khoa học: The role of electrostatic interactions in the antitumor activity of dimeric RNases docx
... data are suggestive of a role of mem- branes, in particular of negatively charged membranes, in the mechanism of action of RNases, we investigated the ability of a series of RNases to destabilize ... shows the shape of the electrostatic field of BS-RNase seen from different directions. Figure S3 compares the electrostatic field of different Fig. 5. Plot of the EIE values a...
Ngày tải lên: 19/02/2014, 06:20
Tài liệu Báo cáo khoa học: The role of antioxidants in the cytotoxicity of chemotherapeutic drugs pptx
... chemical instability of DNA. To protect the vital genetic information from the deleterious effects of DNA injury a net- work of genome care-taking mechanisms has evolved of which a set of DNA repair ... lysosomes. An example of traffic machinery in which abnormalities of function can result in dis- ease is that for formation of multivesicular bodies on the endocy- tic pathway...
Ngày tải lên: 19/02/2014, 07:20
Tài liệu Báo cáo khóa học: The effect of mutations surrounding and within the active site on the catalytic activity of ricin A chain pptx
... the tetraloop structure of such a hexanucleotide, where the conformation of the target adenine had been altered, using the known structures of complexes of RTA with FMP (formycin monophosphate) and ... addition of 100 lLof2· Kirby buffer [25] and 80 lLofH 2 O, and rRNA was obtained by precipitation after two phenol– chloroform extractions. Four micrograms of rRNA were treatedwit...
Ngày tải lên: 19/02/2014, 12:20