Báo cáo Y học: Variations in receptor site-3 on rat brain and insect sodium channels highlighted by binding of a funnel-web spider d-atracotoxin pdf
Báo cáo Y học: Variations in receptor site-3 on rat brain and insect sodium channels highlighted by binding of a funnel-web spider d-atracotoxin pdf
... d-ACTX-Ar1 a nd -Hv 1a com- pletely inhibit the binding of classical scorpion a- toxins (e.g. Aah-II and Lqh-II) to rat brain synaptosomes as well as the binding of LqhaIT to insect sodium channels [29,30]. ... association rate. The binding of 125 I-labelled d-ACTX-Hv 1a to rat brain syna- ptosomes is inhibited c ompetitively by classical ScaTxs and allost...
Ngày tải lên: 08/03/2014, 16:20
Tài liệu Báo cáo Y học: The Fc receptor c-chain is necessary and sufficient to initiate signalling through glycoprotein VI in transfected cells by the snake C-type lectin, convulxin ppt
... of Fura-2 emissions were measured and analyzed using phycoerythrin FWINLAB software. Ratiometric analysis was converted into a concentration of Ca 2+ by measuring R max (maximal fluorescence in lysed, ... measured tyrosine phosphorylation of the FcR c-chain and the tyrosine kinase Syk, which is tyrosine phosphorylated and activated early after GPVI engagement. Phosphorylation...
Ngày tải lên: 22/02/2014, 07:20
Báo cáo khoa học: Aromatic amino-acid residues at the active and peripheral anionic sites control the binding of E2020 (AriceptÒ) to cholinesterases doc
... repeated at least three times to obtain the values of the inhibition constants. Analysis of catalytic parameters The catalytic parameters of wild-type and mutant AChE and BChE were compared by ... States. Structure-activity studies of this class of inhibitors have indicated that both the benzoyl containing functionality and the N-benzylpiperidine moiety are the key features...
Ngày tải lên: 30/03/2014, 20:20
Báo cáo y học: "Low socio-economic status, smoking, mental stress and obesity predict obstructive symptoms in women, but only smoking also predicts subsequent experience of poor health"
... All participants in the population study were physically examined and interviewed by physicians and research nurses. Information concerning education and socio-economic group was obtained ... measured as peak expiratory flow (PEF) by a peak flow meter in 1968-1969 and as PEF, vital capacity (VC) and forced expiratory volume in one second (FEV 1 ) at the 2000-2001...
Ngày tải lên: 31/10/2012, 15:34
Báo cáo y học: "Advances in immunomodulating therapy of HBV infection"
... enhance clearance of HBV. In vitro studies have shown that thymosin α-1 can accelerate T-cell maturation and antigen recognition. It can also stimulate interferon and cytokine production and ... activity for lysis of infected hepatocytes and by stimulating cytokine production for control of viral replication. Nucleoside analogues on the other hand act by suppressing...
Ngày tải lên: 02/11/2012, 11:17
Báo cáo y học: "Advances in Molecular Diagnosis of HBV Infection and Drug Resistance"
... by means of a DNA polymerase [34]. An alternative approach involves differential hybridization to a preexisting panel of membrane-bound probes as illustrated by the commercially available INNO-LiPA ... an additional compensatory mutation in the B subdomain [20], namely the substitution of a leucine by methionine some 20 amino acids upstream from the YMDD domain at posit...
Ngày tải lên: 03/11/2012, 09:41
Tài liệu Báo cáo Y học: Mutations in the docking site for cytochrome c on the Paracoccus heme aa3 oxidase Electron entry and kinetic phases of the reaction pptx
... oxidase from Paracoccus denitrificans. Nature 376, 660–669. 12. Tsukihara, T., Aoyama, H., Yamashita, E., Tomizaki, T., Yamaguchi, H., Shinzawa-Itoh, K., Nakashima, R., Yaono, R. & Yoshikawa, ... sequence by another aromatic side chain, Y1 22. Table 1 summarizes the kinetic effects of single mutations in either residue, and of several double mutants, indicating that in no case...
Ngày tải lên: 22/02/2014, 07:20
Báo cáo Y học: Differences in the binding capacity of human apolipoprotein E3 and E4 to size-fractionated lipid emulsions pot
... plotted as a function of free protein (lg/mL). The con- centrations of Myr 2 Gro-PCho and TO in lipid emulsion fraction 6are110l M and 390 l M , respectively. Binding data was obtained by analytical ... extrusion, and fractionated by sucrose gradient ultracentrifugation [29]. To initially examine the size-fractionated lipid emulsions, phospholipid and triacylglycerol con...
Ngày tải lên: 08/03/2014, 09:20
Báo cáo Y học: The proximal cis-acting elements Sp1, Sp3 and E2F regulate mouse mer gene transcription in Sertoli cells potx
... concentration of RNA was determined by spectrophotometry at 260 nm, and its integrity was assessed by agarose gel electrophoresis. Polyadenylated RNA was prepared by oligo(dT) affinity chromatography using ... 5¢-TGTCCAAGGGT GTACATATCAACAT-3¢ (Mer,sense )and5 ¢-AGCC GAGGATGATGAACATAGAGT-3¢ (Mer,antisense), which generated a 700-bp Mer PCR product; 5¢-CG GCATTCCCTTCAAGGAGAGT-3¢ (Gas...
Ngày tải lên: 08/03/2014, 23:20
Báo cáo Y học: Changes in ultrastructure and the occurrence of permeability transition in mitochondria during rat liver regeneration ppt
... Italy; 2 Department of Zoology, Laboratory of Histology and Comparative Anatomy, University of Bari, Italy; 3 Center for the Study of Mitochondria and Energy Metabolism (CNR) Bari, Italy Mitochondrial ... 5443316, E-mail: csmmmg14@area.area.ba.cnr.it Abbreviations: AAT, aspartate aminotransferase; CsA, cyclosporin -A; GDH, glutamate dehydrogenase; PH, partial hepatectomy; EU, enz...
Ngày tải lên: 24/03/2014, 04:21