... molecularmechanistic insight is adenocarcinoma of the oesopha-gus [2]. This cancer is one of the fastest rising cancersin the west, is taking the place of squamous cell carci-noma as a more common type of ... max)(y-axis). This can then be used to calculateKd of the indicator, which is the inverse log of the x-inter-cept. To label cells with Fura-2, Fura-2AM was used, as the addition of the AM group ... can then be calculated from Eqn (1) where Kd is the dissociation constant of the indicator, R is the ratio of fluorescence (F) at 340 nm and 380 nm (F340 nm⁄ F380 nm), Q is the ratio of Fmin⁄...