Báo cáo khoa học: Role of Ca2+/calmodulin regulated signaling pathways in chemoattractant induced neutrophil effector functions Comparison with the role of phosphotidylinositol-3 kinase ppt
Báo cáo khoa học: Role of Ca2+/calmodulin regulated signaling pathways in chemoattractant induced neutrophil effector functions Comparison with the role of phosphotidylinositol-3 kinase ppt
... multiple intracel-
lular signaling pathways. Therefore, the role of calmodulin,
the major downstream effector of Ca
2+
, in the regulation of
intracellular signaling was analyzed by using the inhibitor
W7. ... counteracts the calcineurin
induced affinity switch of a
5
b
1
integrin in CHO cells,
suggesting also a role for Ca
2+
/calmodulin-dependent
molecules...
Tài liệu Báo cáo khoa học: Synchronization of Ca2+ oscillations: a coupled oscillator-based mechanism in smooth muscle ppt
... 37% of its original size) is typically in
the range 2–3 mm [26].
Finding experimental evidence that electrical cou-
pling is the key ‘spring’ interlinking the Ca
2+
stores
has involved repeating ... junctions could serve as the spring
joining the pendulums in the above analogy. However,
coupling through release of Ca
2+
results in very weak
coupling, as the effective d...
Tài liệu Báo cáo khoa học: Synchronization of Ca2+ oscillations: involvement of ATP release in astrocytes pdf
... and
P2X7 receptors, suggesting the involvement of multiple
pathways in the release. In addition to these, the
release of ATP is partly dependent on Ca
2+
[15] and
SNARE proteins [16], and astrocytes ... events in the
synchronization of SICs [31]. As shown in the right
panel of Fig. 3B, reactive astrocytes increase the
release of glutamate by facilitating Ca
2+...
Tài liệu Báo cáo khoa học: Synchronization of Ca2+ oscillations: a capacitative (AC) electrical coupling model in neuroepithelium pptx
... cytoplasmic domain of cadherin interacts with
F-actin via b-catenin and a-catenin; b-catenin binds
to cadherin and a-catenin, which in turn interacts with
F-actin (Fig. 3A) [24]. Thus b-catenin plays ... pivotal
role in the regulation of cell–cell adhesion. The interac-
tion of b-catenin with cadherin is regulated by tyrosine
phosphorylation of b-catenin [25,26], whi...
Báo cáo khoa học: Modulation of Ca2+ entry and plasma membrane potential by human TRPM4b pptx
... kept
in serum-containing medium instead of Ringer solution
[16]. Interestingly, the gene encoding TRPM4 has been
shown to be one of the genes upregulated during the
transition from prostatic intraepithelial ... alteration in Ca
2+
entry follow-
ing store depletion.
In uence of TRPM4b on ionomycin -induced
membrane depolarization
Ca
2+
entry induced by depletion of intrac...
Tài liệu Báo cáo khoa học: Modulation of a-synuclein aggregation by dopamine in the presence of MPTP and its metabolite pptx
... understanding of the role of various interacting
components. The formation of dopamine–quinone
adducts (because of auto-oxidation of the neurotrans-
mitter), especially dopaminochrome, with a-synuclein,
inhibited ... 1B shows the pattern
seen after the development of the blot. With increase
in time of incubation, the intensity of the band for the
mono...
Tài liệu Báo cáo khoa học: Plasticity of laccase generated by homeologous recombination in yeast docx
... (83%)
or LAC5 (83%). All together, recombination induced
swapping of amino acids for 94 positions (19% of the
residues) in the original LAC3 sequence. The C- and
N-termini of the hybrids were 33–37% ... chimera,
recombination preserved the integrity of domain D1
and the very end part of domain D3, two regions that
interact precisely in the natural laccase fold (F...
Tài liệu Báo cáo khoa học: Characterization of 1H NMR detectable mobile lipids in cells from human adenocarcinomas doc
... specifically bound to
the induction of apoptosis, in agreement with recent
findings [8].
Second, the intensity of the ML signal, correspond-
ing to TG levels, is increased in irradiated MCF-7
cells, ... deconvolution of spectra of the type
shown in Fig. 1A¢, with ML signals of a very low
intensity, was performed as a first step. Deconvolution
of spectra of the t...
Tài liệu Báo cáo khoa học: Attenuation of cardiac mitochondrial dysfunction by melatonin in septic mice ppt
... giving to the control samples a value ¼ 1
after deducting basal and background values. Sepsis
resulted in a significant increase in the transcription of
the mRNA encoding iNOS in heart of iNOS
+ ... ni-
trosation, of mitochondrial components indirectly [35].
The free radical pathways of ONOO
–
are mainly initi-
ated secondary to the reaction of ONOO
–
with CO
2
,...
Tài liệu Báo cáo khoa học: Stimulation of poly(A) synthesis by Escherichia coli poly(A)polymerase I is correlated with Hfq binding to poly(A) tails ppt
... efficient Hfq binding
in vivo or that Hfq interacts with the 5¢rpsO RNA
fragment which contains the translational operator of
the rpsO messenger [37].
The phosphate number at the 5¢ end of the RNA
does ... enzymes. The
Hfq containing DNA fragment was excised with the same
enzymes and ligated into the corresponding sites of pET11c
and then transformed into the E....