... therapy are also problems of evolutionary biology, and so it will be important to integrate evolutionary biologists into our cancer research teams. In addition, evolutionary biology should ... models from population biology and evolutionary game theory to tumor therapeutic strategies. Mol. Cancer Ther. 2, 919–927 (2003). Describes the use of evolutionary and ecological models to ... cancer as an evolutionary process. Predicts sequences of clonal expansions, individual variation in response to interventions and therapeutic resistance.2. Crespi, B. & Summers, K. Evolutionary...