Báo cáo Y học: Double-stranded RNA-activated protein kinase interacts with apoptosis signal-regulating kinase 1 Implications for apoptosis signaling pathways docx
Báo cáo Y học: Mitogen-activated protein kinase kinase negatively modulates ciliary neurotrophic factor-activated choline acetyltransferase gene expression pdf
... in PC12 cells. J. Neurochem. 71 , 11 18 11 26. 13 . Robinson, M.J. & Cobb, M.H. (19 97) Mitogen-activated protein kinase pathways. Curr. Opin. Cell Biol. 9, 18 0 18 6. 14 . Marshall, C.J. (19 94) ... speci®city. Cell. 80, 19 9± 211 . 16 . Garrington, T.P. & Johnson, G.L. (19 99) Organization and regu- lation of mitogen-activated protein kinase signaling pathways. C...
Ngày tải lên: 31/03/2014, 21:21
Tài liệu Báo cáo Y học: Prediction of protein–protein interaction sites in heterocomplexes with neural networks ppt
... and characterize putative protein networks involved in functional pathways [10 ,11 ]. A different but complementary approach for understand- ing which proteins functionally interact is to develop ... from that of a typical protein surface [17 ,18 ]. Similarly, no residue preference for the interacting surfaces has been reported, although a recent study carried out on 6 21 protein...
Ngày tải lên: 21/02/2014, 15:20
Tài liệu Báo cáo Y học: Uncoupling of protein-3 induces an uncontrolled uncoupling of mitochondria after expression in muscle derived L6 cells ppt
... specifically interact with members of the 14 .3.3 protein family [37]. The 14 .3.3 proteins are located in the cytosol where they regulate various aspects o f cell p hysiology. The 14 .3.3 proteins h ave also been ... , 12 9 13 4. 13 .Hinz,W.,Gruninger,S.,DePover,A.&Chiesi,M. (19 99) Properties of the human long and short isoforms of the uncoupling protein- 3 expressed in yeast c...
Ngày tải lên: 21/02/2014, 15:20
Báo cáo Y học: Probing intermolecular protein–protein interactions in the calcium-sensing receptor homodimer using bioluminescence resonance energy transfer (BRET) potx
... G.E. (19 99) Dimerization of the calcium-sensing receptor occurs within the extracellular domain and is eliminated by Cys->Ser mutations at Cys 10 1 and Cys 236 . J. Biol. Chem. 274, 11 629 11 634. 57. ... supplemented with penicillin (10 0 UÆmL )1 ), streptomycin (10 0 lgÆmL )1 ), 10 % dialyzed fetal calf serum and 1 lCiÆmL )1 myo-[2– 3 H]inositol (Amersham, Bucking- hamshire...
Ngày tải lên: 08/03/2014, 09:20
Báo cáo Y học: Transient activation of the c-Jun N-terminal kinase (JNK) activity by ligation of the tetraspan CD53 antigen in different cell types pptx
... binstein, E. (19 99) S elective tetraspan-integrin complexes (CD 81/ alpha4beta1, CD1 51/ alpha3beta1, CD1 51/ alpha6beta1) under c onditions disrupting tetraspan int eractions. Biochem. J. 340, 10 3 11 1. Ó ... & Akagi,T. (19 97)Anti-CD53 monoclonal antibody induced LFA -1/ ICAM -1- dependent and -independent lymphocyte homotypic adhesion. Immunobiology 19 7, 70– 81. 8. Levy, S., To...
Ngày tải lên: 08/03/2014, 22:20
Báo cáo Y học: Cloning and characterization of the mammalian-specific nicolin 1 gene (NICN1) encoding a nuclear 24 kDa protein doc
... recognized by U1/U2 containing spliceosomes [10 ]. In human, dog and mouse the NICN1 gene is immediately followed by the AMT gene for aminomethyltransferase, an enzyme of glycine meta- bolism [4 ,11 ]. ... 50 mgÆmL )1 streptomycin (denoted met-free medium). Cells were solu- bilized with 1 mLÆdish )1 of cold lysis buffer essentially as described before [8]. The lysates were incubated...
Ngày tải lên: 23/03/2014, 21:20
Báo cáo Y học: SF2/ASF protein inhibits camptothecin-induced DNA cleavage by human topoisomerase I potx
... I. Enzymes: DNA topoisomerase I (EC 5.99 .1. 2). (Received 18 February 2002, revised 20 May 2002, accepted 31 May 2002) Eur. J. Biochem. 269, 3504–3 510 (2002) Ó FEBS 2002 doi :10 .10 46/j .14 32 -10 33.2002.03037.x scleroderma ... antibody to human topo I (TopoGEN). Relaxing activity of the enzyme was 6 .1 · 10 6 ±2.2· 10 6 (n ¼ 4) units per mg protein. Htopo I was also active as a...
Ngày tải lên: 24/03/2014, 03:21
Báo cáo Y học: Selection of effective antisense oligodeoxynucleotides with a green fluorescent protein-based assay Discovery of selective and potent inhibitors of glutathione S-transferase Mu expression doc
... was only slightly lower than that of EGFP itself [2 .1 ± 0 .1, 1. 7 ± 0 .1, and 1. 8 ± 0 .1 (· 10 3 arbitrary units) for EGFP, EGFP–M1, and EGFP–M2, respectively], indicating that the EGFP moiety of ... EGFP-M1 EGFP-M2 AS-ODN % of EGFP control % of EGFP control % of EGFP-M1 control % of EGFP control % of EGFP-M2 control – 10 0 ± 6 340 ± 16 10 0 ± 6 19 0 ± 11 10 0 ± 7 AS-5 93 ± 7...
Ngày tải lên: 31/03/2014, 15:20
Báo cáo Y học: LRP130, a protein containing nine pentatricopeptide repeat motifs, interacts with a single-stranded cytosine-rich sequence of mouse hypervariable minisatellite Pc-1 docx
... with aF-N without competitors; and with competitors, lanes 4, 5 and 6, with C8; lanes 7, 8 and 9, with C5; lanes 10 , 11 and 12 , with C5Pc-2; lanes 13 , 14 and 15 , with C5gg; lanes 16 , 17 and 18 , ... extracts, 1 · 10 7 NIH3T3 cells were harvested and washed with NaCl/P i , lysed with a 5 cell- pack vol. of lysis buffer consisting of 50 m M Tris/HCl (pH 8.0),...
Ngày tải lên: 31/03/2014, 23:20
Báo cáo y học: "Medical resource utilization among patients with ventilator-associated pneumonia: pooled analysis of randomized studies of doripenem versus comparators"
... 1 (1. 6) 1 (1. 6) 1 (0.4) 5 (2.0) 2 (0.6) 6 (1. 9) VAP onset Early (<5 days) 63 (10 0.0) 61 (10 0.0) 98 (39.4) 97 (38.5) 16 1 ( 51. 6) 15 8 (50.5) Late (≥5 days) 0 (0.0) 0 (0.0) 15 1 (60.6) 15 5 ( 61. 5) ... 1. 31 1.09 -1. 58 0.004 VAP onset (early) 1. 30 1. 08 -1. 57 0.005 Baseline P. aeruginosa (presence) 0.83 0.62 -1. 11 0. 212 Region (North America) 1. 51 1.25 -1. 82...
Ngày tải lên: 25/10/2012, 10:02