Báo cáo Y học: Rodent a-chymases are elastase-like proteases pot
Báo cáo Y học: Rodent a-chymases are elastase-like proteases pot
... homology with other a-chymases of primates and dogs, rodent a-chymases were predicted to be chymo- trypisin-like proteases that have very similar substrate spe- cificity to those of other a-chymases. ... rodent a-chymases with Val216 (Fig. 6). These results strongly suggest that all four rodent a-chymases are elastase-like proteases that are evolutionarily close to eac...
Ngày tải lên: 08/03/2014, 09:20
Tài liệu Báo cáo Y học: Short peptides are not reliable models of thermodynamic and kinetic properties of the N-terminal metal binding site in serum albumin doc
... ¼ 1 and n ¼ 3. b Ni(II) data from ref [11]. c [31]. d [36]. e glycylglycylhistamine, [9]. f a-hydroxymetylseryl-a-hydroxymetylserylhistidinamide; Cu(II) data from [37]; Ni(II) data from [38]. g N-Terminal ... pooled and lyophilized to yield with solid of purity exceeding 99% as assessed by HPLC analysis of the final m aterials. I dentity and purity of peptide was confirmed by mass spectrometry,...
Ngày tải lên: 22/02/2014, 04:20
Tài liệu Báo cáo Y học: Transactivation domains are not functionally conserved between vertebrate and invertebrate serum response factors potx
... transduction pathways, such as the classical ternary complex factors, that are activated by MAP-kinase pathways [18]. Several nonvertebrate SRF homologues have been described that are mainly involved ... was kindly provided by U. Moe ¨ ns (University of Tromso, Norway) [31]. The expression vector pcDNA3-myc was generated by inserting a BamHI–EcoRI fragment that codes for six copies of myc...
Ngày tải lên: 22/02/2014, 07:20
Báo cáo y học: "Characterization of Human Erythrocytes as Potential Carrier for Pravastatin: An In Vitro Study"
... com- pared to that of unloaded erythrocytes (Table 4). Table 4, Erythrocyte osmotic fragility of unloaded eryth- rocytes and erythrocytes loaded with 8, 4 and 2 mg/ml pravastatin. Values are ... in erythrocytes either by physical methods such as endocytosis and osmosis-based systems or by chemical perturbation of the erythrocytes membrane [16]. Endocytosis is the process by which ce...
Ngày tải lên: 25/10/2012, 11:10
Báo cáo Y học: Characterization of a low redox potential laccase from the basidiomycete C30 pptx
... (one type 2 and two type 3) responsible for the four electron reduction of dioxygen [3]. These enzymes are common in plants, fungi, insects and bacteria [1]. In plants, they may mainly play a role ... basidiomycete produces, in vivo,enzyme forms with such different behaviors are discussed. Keywords: metalloenzyme; copper; redox potential; laccase; basidiomycete C30. Laccases (EC 1.10.3.2)...
Ngày tải lên: 08/03/2014, 09:20
Báo cáo y học: "Why are some children with early onset of asthma getting better over the years" -aneuploid-prostate-cancer-cells-after-tmz-tmz-bioshuttle-treatment.html#post143974
... (19). Interestingly, the exposition for pet animals tended to be higher in the NA cases, which may support the hygiene hypothesis, but may also be due to higher sensitivity in the A group. ... hospital or primary health care diagnosis of asthma at least once between 0-7 years of age in a total birth-year cohort in a defined Swedish geographical area. A multiple logistic analysis reveale...
Ngày tải lên: 26/10/2012, 09:48
Báo cáo y học: "PARP-1 inhibitors: are they the long-sought genetically specific drugs for BRCA1/2-associated breast cancers"
... evolutionarily conserved BRC motifs in the human breast cancer susceptibility gene brca2. J Biol Chem 1997; 272: 31941-4. 29. Bryant HE, and Helleday T. Poly(ADP-ribose) polymerase inhibitors as potential ... V-C8, compared with the BRCA2 wild type control, exhibited extreme sensitivity to AG14361, a very potent PARP-1 inhibitor (K I =5nM), and NU1025, a moderately potent PARP-1 inhibi...
Ngày tải lên: 31/10/2012, 16:57
Báo cáo y học: "Prion propagation in vitro: are we there yet"
... infectivity. Autocatalytic Conversion Assay Baskakov developed a novel in vitro system re- ferred to as the autocatalytic conversion assay. The principle of this assay heavily relies on ... infectivity. 23 Cell-Lysate Conversion Assay Saborio et al. introduced a system termed the cell-lysate conversion assay. 24 This method describes incubating lysate of Chinese hamster ovary cell...
Ngày tải lên: 03/11/2012, 11:52
Tài liệu Báo cáo Y học: Phosphatidylinositol synthesis and exchange of the inositol head are catalysed by the single phosphatidylinositol synthase 1 from Arabidopsis docx
... phosphatidylinositol; PtdOH, phosphatidic acid; CDP-DAG, CDP-diacylglycerol; CMP, cytidine monophosphate; CTP, cytidine triphosphate. Enzymes: phosphatidylinositol synthase or CDP-diacylglycerol/ myo-inositol ... novo synthesis, catalysed by phosphatidylinositol synthase (EC 2.7.8.11), also known as CDP-diacylglycerol (DAG)/myo- inositol 3-phosphatidyltransferase, and an exchange reac- tion w...
Ngày tải lên: 22/02/2014, 04:20
Báo cáo Y học: Two GPX-like proteins from Lycopersicon esculentum and Helianthus annuus are antioxidant enzymes with phospholipid hydroperoxide glutathione peroxidase and thioredoxin peroxidase activities pptx
... selenocysteine in mammal GPXs. The selenocysteine residue is important for the catalytic activity of GPX as replacement of selenocysteine by cysteine greatly reduces the activity of the enzyme [12]. According ... affinity towards phospholipid hydroperoxides and a weaker affinity towards t-butyl hydroperoxide, as indicated by their respective apparent K m values. There was no detectable activity...
Ngày tải lên: 08/03/2014, 22:20