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Báo cáo Y học: The presence of a helix breaker in the hydrophobic core of signal sequences of secretory proteins prevents recognition by the signal-recognition particle in Escherichia coli doc

Báo cáo Y học: The presence of a helix breaker in the hydrophobic core of signal sequences of secretory proteins prevents recognition by the signal-recognition particle in Escherichia coli doc

Báo cáo Y học: The presence of a helix breaker in the hydrophobic core of signal sequences of secretory proteins prevents recognition by the signal-recognition particle in Escherichia coli doc

... SRPpathway, the targeting pathway that is exploited by integralinner-membrane proteins. Together, these data indicatethat the helix breaker in cleavable signal sequences prevents recognition by ... The presence of a helix breaker in the hydrophobic core of signal sequences of secretory proteins prevents recognition by the signal- recognition particle in Escherichia coli Hendrik Adams1, ... Bernstein, H.D. (2001) The targeting pathway of Escherichia coli presecretory and integral membrane proteins isspecified by the hydrophobicity of the targeting signal. Proc. Natl.Acad. Sci. USA 98,...
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Báo cáo y học:

Báo cáo y học: " Laugh Yourself into a Healthier Person: A Cross Cultural Analysis of the Effects of Varying Levels of Laughter on Health"

... via the motor cortex and pyramidal tract to the ventral brain stem. The involuntary path is comprised of amygdala, thalamic, hypothalamic, and subtha-lamic areas, in addition to the dorsal ... to be in the range of ten to twenty-five laughs in one day, and on the situational laughter scale, a rating of four to seven. Clinically, laughter history can be obtained by asking the indi-vidual ... Hunaid Hasan, Tasneem Fatema Hasan Mahatma Gandhi Mission’s Medical College, Aurangabad, Maharastra, India, 431003  Correspondence to: Hunaid Hasan or Tasneem Fatema Hasan, “Ezzi Manzil”,...
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Tài liệu Báo cáo Y học: CK2btes gene encodes a testis-specific isoform of the regulatory subunit of casein kinase 2 in Drosophila melanogaster potx

Tài liệu Báo cáo Y học: CK2btes gene encodes a testis-specific isoform of the regulatory subunit of casein kinase 2 in Drosophila melanogaster potx

... responsible for the downregulation of catalytic activity of a subunit towardcalmodulin and for the activation by polybasic compounds. The examination of amino-acid alignment in the acidicregion of three ... protein -A Sepharose,washed and separated by SDS/PAGE. The immunostaining of Western blot was performed by commercially available,high affinity anti-(b-galactosidase) Ig.Anti-(b-galactosidase) ... encodes a testis-specific isoform of the regulatorysubunit of casein kinase 2 in Drosophila melanogasterAlla I. Kalmykova1, Yuri Y. Shevelyov1, Oksana O. Polesskaya1,*, Anna A. Dobritsa1,†,Alexandra...
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Báo cáo Y học: Cytochrome c from a thermophilic bacterium has provided insights into the mechanisms of protein maturation, folding, and stability potx

Báo cáo Y học: Cytochrome c from a thermophilic bacterium has provided insights into the mechanisms of protein maturation, folding, and stability potx

... thermophilic bacteria are usuallystable to heat and chemical denaturants, indicating that theymust have most of the determinants of protein stability.Initial clues to the relationship between protein ... protein into an artificial one with stability similarto that of the natural thermophile by replacing a few amino-acid residues. Therefore, the thermophilic character of HT c-552 may depend on a ... Yamazaki, T. & Sambongi, Y. , Yu, Y. , Igarashi, Y. , Kodama, T., Yamazaki, K., Kyogoku, Y. &Kobayashi, Y. (1998) Solution structure of thermostable cyto-chrome c-552 from Hydrogenobacter...
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Báo cáo Y học: Arginine 121 is a crucial residue for the specific cytotoxic activity of the ribotoxin a-sarcin potx

Báo cáo Y học: Arginine 121 is a crucial residue for the specific cytotoxic activity of the ribotoxin a-sarcin potx

... Proteins exhibiting ribonucleaseactivity appear as colourless bands after proper destainingtreatment. Hydrolysis of adenylyl(30!50)adenosine (ApA) by a- sarcin and the mutant variants was ... and base on the catalysis by a- sarcin [19,20],rendered proteins with no detectable activity against ApA[20]. Cleavage of ApA by a- sarcin is a low-specificityreaction requiring high amounts of ... already proposedthat the mechanism of action of a- sarcin against ribo-somes might differ in some details from that against dinuc-leotides [18,19]. The behaviour of a- sarcin against ApA as a function...
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Báo cáo y học: Esterified Hyaluronic Acid and Autologous Bone in the Surgical Correction of the Infra-Bone Defects

Báo cáo y học: Esterified Hyaluronic Acid and Autologous Bone in the Surgical Correction of the Infra-Bone Defects"

... feature allows HA to maintain conformational stiffness and to retain water. One gram of HA can bind up to 6 L of water [6]. As a physical background material, it has functions in space filling, ... with a mean depth of 8.3 mm of the infra-bone defects, as revealed by intra-operative probes. Data were obtained at baseline before treatment and after 10 days, and subsequently at 6,9, and ... matrix and scavenging of free radicals [4,5]. However, recent data indicated a certain role played by undersulfated glycosaminoglycans, such as HA, on hydroxyapatite crystal formation [7]. Moreover,...
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Báo cáo Y học: Protein methylation as a marker of aspartate damage in glucose-6-phosphate dehydrogenase-deficient erythrocytes docx

Báo cáo Y học: Protein methylation as a marker of aspartate damage in glucose-6-phosphate dehydrogenase-deficient erythrocytes docx

... different erythrocyte age/density fractions obtained by isopycnic centrifugation on a Percoll gradient. Methyl esterification in intact erythrocytes was assayed by incubating them in the presence of [3H]methionine ... erythrocytepopulation [5]. These observations indicate that biochemicalalterations that occur naturally during erythrocyte ageingare part of the mechanism of haemolysis induced by oxidative stress in these ... methylation assays were per-formed by incubating intact erythrocytes in the presence of methyl-labelled methionine. Altered aspartate residues weredetected in membrane proteins by methyl ester...
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Báo cáo Y học: Endogenous cardiac glycosides, a new class of steroid hormones pot

Báo cáo Y học: Endogenous cardiac glycosides, a new class of steroid hormones pot

... of a ouabain-binding antibodylowered the NaCl-dependent rise in the amount of ACEmRNA, which may indicate that the increase in ACEmRNA is secondary to the activation by brain ÔouabainÕ[73]. ... activity of the ACE in hypothalamus and pons of Dahlsalt-sensitive rats without a parallel increase in angioten-sin II levels. Chronic blockade of brain ÔouabainÕ by intraventricular infusion of a ... Ouabain is also taken up by cultured adrenal cells [28]. Consistent with the adrenal glandbeing a major place of synthesis and/or storage of ouabain,adrenalectomy leads to a lowering of ouabain...
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Báo cáo Y học: Human sprouty 4, a new ras antagonist on 5q31, interacts with the dual specificity kinase TESK1 potx

Báo cáo Y học: Human sprouty 4, a new ras antagonist on 5q31, interacts with the dual specificity kinase TESK1 potx

... level of Raf/MAP kinase [3]. Human sprouty family members areassumed to exert a function similar to inhibitors of the ras/MAP kinase signaling pathway that are induced by activated ras itself, ... without anysubstantial open reading frame. The longest transcript(7 kb) harbors five polyadenylation sites (two AATAAA,and three AATTAAA), nine ATTTA sequences [23], twoAlu-repeats and three CAGAC ... constructed.Kinase activity of cotransfected Myc-tagged MAP kinasewas measured by its ability to phosphorylate myelin basicprotein and was maximal 2 min after stimulation withinsulin or EGF; hspry4 inhibited...
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Báo cáo y học:

Báo cáo y học: "Do we need a critical care ultrasound certification program? Implications from an Australian medical-legal perspective"

... accepting the fee, the doctor has a contractual duty to provide a AbstractMedical practitioners have a duty to maintain a certain standard of care in providing their services. With critical care ... perform a vaginal hysterectomy that was beyond the capacity of the registrar in question. As a result of poor surgical skills, the patient’s fallopian tube was entrapped in the suture line and later ... become an indispensable tool in the next few years. In fact, many ICUs nowadays have an ultrasound machine available in their units, or at least accessible in the hospitals. Considering the benefi...
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