Báo cáo Y học: Role of three isoforms of phospholipase A2 in capacitative calcium influx in human T-cells pot

... Faculty, Selcuk University, Konya, Turkey. 3. Department of Biochemistry, Meram Medical Faculty, Selcuk University, Konya, Turkey. 4. Department of Pulmonary Medicine, Meram Medical Faculty, Selcuk ... flow for a minimum of 10 sec, was considered as hypopnea. Individuals with an apnea hypopnea index (AHI) >5 were diagnosed as OSAS and included in the study. Determining of A...

Ngày tải lên: 25/10/2012, 11:00

... in a variety of physiological events. The regulatory functions of sPLA 2 -IIA, a prototypic proinflammatory sPLA 2 , have been investigated in a number of studies [3–18]. In general, this enzyme ... Gifu, Japan; 3 Institute of Molecular and Cellular Biosciences, University of Tokyo, Tokyo, Japan; 4 College of Pharmacy, Yeungnam University, Gyonsan, Korea Group IID secretory...

Ngày tải lên: 18/03/2014, 01:20

... capacita- tive calcium entry in these cells. These results suggest that stimulation of three isoforms of PLA 2 by thapsigargin liberates free AA that, in turn, induces capacitative calcium in ux in human T-cells. Keywords: ... mRNA of four PLA 2 isotypes (type IB, type V, type IV and type VI). Interestingly, addition of TG stimulated the induction of the four PL...

Ngày tải lên: 08/03/2014, 09:20

... safety and efficacy of three bone health Plans using three independent sequentially enrolled groups of healthy women 40 years of age and older. The pri- mary outcome measure was changes in baseline ... density (BMD) by ensuring that they are getting the recommended amounts of calcium and vitamin D 3 , and that supplementation may be helpful in meeting these nutritional...

Ngày tải lên: 25/10/2012, 11:10

... obesity. In obese humans, dietary soy protein also reduces body weight and body fat mass in addition to reducing plasma lipids. Several potential mechanisms whereby soy protein may improve insulin ... actions of certain constituents of soy protein, particularly conglycinin, soyasaponins, phospholipids, and isoflavones, that relate to obesity are also discussed. In addition, the p...

Ngày tải lên: 31/10/2012, 14:59

... N-terminal lumenal helix of PsaF has been shown to be involved in binding of plastocyanin [9,10]. In cyanobacteria, deletion of PsaF did not change the kinetics of photosystem I reduction by either ... protein plastocyanin can be replaced by cytochrome c 6 , a redox protein of similar size but entirely different folding, in a number of eukaryotic algae and cyanobacteria incl...

Ngày tải lên: 21/02/2014, 01:21

... Role of sulfoquinovosyl diacylglycerol for the maintenance of photosystem II in Chlamydomonas reinhardtii Ayumi Minoda 1 , Norihiro Sato 1 , Hisayoshi Nozaki 2 , Katsuhiko ... sulfoquinovosyl diacylglycerol; photosystem II; Chlamydomonas; thylakoid membrane; glycolipid. The primary process in photosynthesis occurs in thylakoid membranes. Protein complexes such as photosystem ... s...

Ngày tải lên: 22/02/2014, 04:20

... E301 in modulating the flavin potential [18], and that it might only provide an alternative means of providing protons to the flavin ring to produce the hydroquinone form upon reduction of the enzyme ... determine experimentally either the K d or the binding energies for the apoFNR:FAD complexes in any redox state. However, as the reduction potentials of free and bound FAD are linked...

Ngày tải lên: 08/03/2014, 23:20

... chain of tyrosine 229. This displacement may be facilitated involving by R389 through lowering the pK of the tyrosine hydroxyl group. The proton is delivered to the carboxybiotin and catalyzes ... pH optimum of the enzyme was between pH 6.3 and 6.9. Interestingly, the affinity of the enzyme for Na + increased approximately twofold on increasing the pH from 5.6 to 6.9 or 8.3 and simulta...

Ngày tải lên: 08/03/2014, 23:20

... form) (compare the position of Y2 38 in Fig. 1A with that in Fig. 1B). To obtain an insight of the role of Y2 38 in RgDAAO we produced and characterized two single-point mutations at site Y2 38 of RgDAAO. MATERIALS ... phe- nylalanine and serine in the enzyme from the yeast Rhodo- torula gracilis. The mutated proteins are catalytically competent thus eliminating Tyr238 as...

Ngày tải lên: 17/03/2014, 17:20