Báo cáo Y học: Inhibition of hyaluronan synthesis in Streptococcus equi FM100 by 4-methylumbelliferone doc
Báo cáo Y học: Inhibition of hyaluronan synthesis in Streptococcus equi FM100 by 4-methylumbelliferone doc
... of the hyaluronan synthase from Strepto- coccus pyogenes. J. Biol. Chem. 276, 2037–2046. Ó FEBS 2002 Inhibition of HA synthesis in Streptococcus by MU (Eur. J. Biochem. 269) 5075 Inhibition of ... n-dodecyl-b- D -maltoside; GlcNAc, N-acetylglucosamine; GlcUA, glucuronic acid; HA, hyaluronan (hyaluronic acid); HABP, hyaluronan binding protein; HAS (Has), hyaluronan sy...
Ngày tải lên: 08/03/2014, 09:20
Tài liệu Báo cáo Y học: Inhibition of the MEK/ERK signaling pathway by the novel antimetastatic agent NAMI-A down regulates c-myc gene expression and endothelial cell proliferation ppt
... and ultimately abolished, the increase in c-myc gene expression elicited by PMA in serum-free cells. These results suggest that inhibition of MEK/ERK signaling by NAMI-A may have an important role in modulating ... be lying upstream of ERK1/2. Recent observations indicate that activation of Raf by PMA may trigger the same signaling pathway as oncogenic Raf, or Raf activati...
Ngày tải lên: 21/02/2014, 01:21
Tài liệu Báo cáo Y học: Inhibition of nuclear pre-mRNA splicing by antibiotics in vitro pot
... was reduced by 60% in the presence of 500 l M Cl-tetracycline and by 95% in t he presence of 500 l M erythromycin and streptomycin (Fig. 2B,C). Tetracycline at 500 l M inhibited splicing by only 1 0% ... splicing inhibition by tetracycline is n egligible (Fig. 2). The sixfold stron ger splicing inhibition by Cl-tetracycline may be explained by the a dditional s ize and...
Ngày tải lên: 21/02/2014, 15:20
Báo cáo Y học: Inhibition of the SERCA Ca21 pumps by curcumin Curcumin putatively stabilizes the interaction between the nucleotide-binding and phosphorylation domains in the absence of ATP pot
... processes including: activation of apoptosis in Jurkat T-cells [5], inhibition of platelet aggregation [6,7] and inhibition of in ammatory cytokine production in macrophages [8]. Curcumin has also ... activity of a number of key enzymes such as cyclooxygenase [9], protein kinase C [10], protein tyrosine kinases [11] and a Ca 2þ -dependent endonuclease [12]. Many of these...
Ngày tải lên: 08/03/2014, 23:20
Báo cáo Y học: Modulation of inositol 1,4,5-triphosphate concentration by prolyl endopeptidase inhibition ppt
... Auerswald, E.A. (1995) Temporary inhibition of papain by hairpin loop mutants of chicken cystatin. Distorted binding of the loops results in cleavage of the Gly(9)-Ala10 bond. FEBS Lett. 361, ... a serine peptidase characterized by oligopeptidase activity. It is grouped in family S9A in clan SC [1]. Enzymes belonging to clan SC are distinct from trypsin-type and subtilisin...
Ngày tải lên: 31/03/2014, 08:20
Báo cáo Y học: Inhibition of glycosyl-phosphatidylinositol biosynthesis in Plasmodium falciparum by C-2 substituted mannose analogues pot
... organisms. In all systems investigated so far, mannosamine was able to inhibit GPtdIns biosynthesis. In T. brucei, mannosamine inhibits the incorporation of ethanolamine into GPtdIns protein by being incorporated into ... study glycosylphosphatidylinositol (GPtdIns) biosynthesis and GPtdIns protein anchoring in protozoal and mammalian systems. The effects of these analogues on GPt...
Ngày tải lên: 31/03/2014, 23:20
Báo cáo Y học: Inhibition of SERCA Ca2+ pumps by 2-aminoethoxydiphenyl borate (2-APB) 2-APB reduces both Ca2+ binding and phosphoryl transfer from ATP, by interfering with the pathway leading to the Ca2+-binding sites ppt
... permeability studies The effect of 2-APB on membrane permeability was monitored by assessing the quenching of calcein dye trapped in egg phosphatidylcholine liposomes by Co 2+ , as described by Longland ... inhibition of SERCA (Eur. J. Biochem. 269) 3687 Inhibition of SERCA Ca 2+ pumps by 2-aminoethoxydiphenyl borate (2-APB) 2-APB reduces both Ca 2+ binding and phosphory...
Ngày tải lên: 31/03/2014, 23:20
Báo cáo y học: " Predictors of hepatic steatosis in HBeAg-negative chronic hepatitis B patients and their diagnostic values in hepatic fibrosis"
... with clinically and pathologically proven steatosis and 98 patients without steatosis were recruited into this study. The levels of fasting blood glucose (FBG), fasting insulin (FINS), triglyceride ... levels of serum alanine aminotransferase (ALT). The higher prevalence of hepatic steatosis in Hispanics was mainly due to the higher prevalence of obesity and insulin resistance...
Ngày tải lên: 25/10/2012, 11:48
Báo cáo y học: "Management of HBV Infection in Liver Transplantation Patients"
... contributing to the efficacy of combination LAM and HBIG remain poorly defined. Postulated mechanisms include the synergy of: 1) LAM reducing HBV replication and altering synthesis of HBsAg necessary ... finding of circulating HBV DNA by PCR in 2 of 11 receiving HBIG and 5 of 10 receiving LAM suggests that reinfection would be likely in additional patients with longer ob...
Ngày tải lên: 02/11/2012, 11:17
Tài liệu Báo cáo khoa học: Interruption of triacylglycerol synthesis in the endoplasmic reticulum is the initiating event for saturated fatty acid-induced lipotoxicity in liver cells pdf
... remark- ably different effects. Exposure of a variety of cell types, including hepatocytes, to long-chain saturated fatty acids (SFAs) led to increased expression of proin- flammatory cytokines, inhibition ... of phosphatidylcholine ⁄ phosphatidylserine bilayers. Biophys J 66, 382–393. 31 Mori T, Takai Y, Yu B, Takahashi J, Nishizuka Y & Fujikura T (1982) Specificity of the f...
Ngày tải lên: 14/02/2014, 22:20