Báo cáo Y học: Modulation of the oligomeric structures of HIV-1 retroviral enzymes by synthetic peptides and small molecules pptx
Báo cáo Y học: Modulation of the oligomeric structures of HIV-1 retroviral enzymes by synthetic peptides and small molecules pptx
... REVIEW ARTICLE Modulation of the oligomeric structures of HIV-1 retroviral enzymes by synthetic peptides and small molecules Nicolas Sluis-Cremer1 and Gilda Tachedjian21Department of Medicine, ... of the oligomeric structures of HIV-1 viral enzymes by synthetic peptides and small molecules. ACKNOWLEDGEMENTS The authors would like to acknowledge Dominique Arion for criticalreading of the ... identification of synthetic peptides and small mole-cules that specifically target the subunit–subunit interfaces of these retroviral enzymes, resulting in the inactivation of theirenzymatic functioning.Keywords:...
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Báo cáo y học: "Foundation for the Community Control of Hereditary Diseases, Budapest, Hungary"
... Czeizel Foundation for the Community Control of Hereditary Diseases, Budapest, Hungary Corresponding address: Andrew E. Czeizel Foundation for the Community Control of Hereditary Diseases, 1148 Budapest, ... epicanthal folds, ocular hypotelorism, preauricular tags and pits, low-set ears, simian crease, clino- and camptodactyly, partial syndactyly between toes 2 and 3, hydrocele, umbilical hernia, ... used the term birth (live- and stillbirths) prevalence in the past. However, recently the different methods of prenatal diagnoses have been used widely for the detection of fetal defects and...
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Báo cáo y học: "Gene Therapy: The Potential Applicability of Gene Transfer Technology to the Human Germline"
... certainty that the effect is a real one. Secondly, it could be the case that the trangene molecules bound only weakly to the sperm cells, such that only direct delivery (by ICSI) permitted the ... microscope, the needle is guided through the cytoplasm towards one of the zygote’s pronuclei. A nanolitre quantity of DNA solution is injected, bringing typically two hundred DNA molecules into the ... Transfer The genome of retroviruses can be manipulated to carry exogenous DNA. Retroviral vectors (RVVs) are one of the most frequently employed forms of gene delivery in somatic gene therapy [15,...
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Tài liệu Báo cáo Y học: Insights into the reaction mechanism of Escherichia coli agmatinase by site-directed mutagenesis and molecular modelling ppt
... of the loop indicated by the letter a.Fig. 5. Scheme of the binuclear manganese cluster and the localization of the side-chains of Asp153 and Asn153 in the modelled structures of wild-type and ... indicating that the environ-ment of tryptophan residues is essentially conserved in the mutant enzyme. On the other hand, the absence of majordifferences in the CD spectra of the wild-type and D153Nagmatinases ... caldovelox and rat liver arginases alsoFig. 2. Effect of added Mn2+ and EDTA on the catalytic activity of wild-type and D153N agmatinase. The enzymes were assayed before(Control) and after dialysis...
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Tài liệu Báo cáo Y học: Studies on the nonmevalonate pathway of terpene biosynthesis The role of 2C-methyl-D -erythritol 2,4-cyclodiphosphate in plants docx
... 2C-methyl-D-erythritol4-phosphate can be converted into a cyclic diphosphate by the consecutive action of 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, 4-diphosphocytidyl-2C-methyl-D-erythritolkinase ... exchange (2% of the isomerization rate) of the methyl group of IPP and the (Z)-methyl group of DMAPP, and an even slower exchange(0.5% of the isomerization rate) of the olefinic hydrogen of DMAPP corresponding ... exchange of the HA-hydrogen of IPP. Inboth cases, scrambling of the label takes place within the IPPpool and the error is then transcribed into the DMAPP pool by the normal action of the isomerase....
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Báo cáo Y học: Differences in the binding capacity of human apolipoprotein E3 and E4 to size-fractionated lipid emulsions pot
... Peter Schuck2 and Geoffrey J. Howlett11Department of Biochemistry and Molecular Biology, The University of Melbourne, Parkville, VIC, Australia;2Division of Bioengineering and Physical Science, ... (IDL), and a subclass of high density lipoprotein(HDL) [11–13]. It serves as a high-affinity ligand for anumber of cell surface receptors, thereby mediating the uptake of cholesterol and other ... and 34 297 Da,respectively) determined by electrospray mass spectrometryagree well with theoretical values and known differencesbetween the amino acid compositions of the isoforms [15].Dynamic...
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Báo cáo y học: " Polysaccharides from the root of Angelica sinensis protect bone marrow and gastrointestinal tissues against the cytotoxicity of cyclophosphamide in mice
... marrow and the gastrointestinal tissues from the cytotoxicity of CY in mice. We also profiled the changes of the expression of growth factors in gastric tissues in response to the damage by CY and ... Immunology and Department of Pharmacology, Faculty of Medicine, The University of Hong Kong, Hong Kong, China Corresponding address: Prof. C.H. Cho, Department of Pharmacology, The University of ... probably supply more nutrients and oxygen to gastric and duodenal mucosae. This also promoted the defensive mechanism and also the repairing capacity of the GI system which has been damaged by CY...
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Báo cáo y học: "Update on the treatment of ocular toxoplasmosis"
... by Rothova et al was 250mg a day or 500mg every other day and therapy was associated with pyrimethamine 100mg on the first day that was fol-lowed by 50mg a day. Prophylaxy of recurrence of ... survey of the opinion of oph-thalmic specialists in uveitis was performed recently by Gary Holland. [3] The reasons that were commonly accepted to introduce a therapy were the following: a) the ... usually asymptomatic and can present flu-like symptoms. A dissemination of the parasites occurs and the tissular cysts will persist during the all life of the host. An ocular reactivation of the...
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Tài liệu Báo cáo Y học: A Raman optical activity study of rheomorphism in caseins, synucleins and tau New insight into the structure and behaviour of natively unfolded proteins pot
... . The X-ray crystal structure 1 pi2 reveals that the /,w angles of most of the residues of the Bowman±Birk inhibitor aredistributed fairly evenly over the b- and PPII-regions of the Ramachandran ... protein structures areoften called r andom coil, implying that they behave like synthetic high polymers in dilute aqueous solution for which the r andom coil model was originally developed. The random ... strands, they would be expected to readily undergo thistype of aggregation w ith each other and a lso with the edges of established bsheet. The m ore d ynamic type of disorderassociated with the...
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Tài liệu Báo cáo Y học: Mutations in the docking site for cytochrome c on the Paracoccus heme aa3 oxidase Electron entry and kinetic phases of the reaction pptx
... hypotheticalsecond site have been made here for the bacterial enzyme by stripping subunits III and IV off the native complex, and by further destroying a large part of the acidic lobe(s) of the docking ... complex of the respiratory chains of mitochondria and many bacteria[1–4]. It catalyzes the reduction of oxygen to water, coupling the free energy of this reaction to the generation of a protongradient ... (a) the presence of subunits III2986 V. Drosou et al.(Eur. J. Biochem. 269) Ó FEBS 2002andIVintheParacoccus enzyme, and by inference on the presence of cytoplasmically coded subunits of the...
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Từ khóa: Nghiên cứu sự biến đổi một số cytokin ở bệnh nhân xơ cứng bì hệ thốngBáo cáo quy trình mua hàng CT CP Công Nghệ NPVGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitĐỒ ÁN NGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWANPhát triển mạng lưới kinh doanh nước sạch tại công ty TNHH một thành viên kinh doanh nước sạch quảng ninhPhát triển du lịch bền vững trên cơ sở bảo vệ môi trường tự nhiên vịnh hạ longNghiên cứu, xây dựng phần mềm smartscan và ứng dụng trong bảo vệ mạng máy tính chuyên dùngThơ nôm tứ tuyệt trào phúng hồ xuân hươngThiết kế và chế tạo mô hình biến tần (inverter) cho máy điều hòa không khíChuong 2 nhận dạng rui roKiểm sát việc giải quyết tố giác, tin báo về tội phạm và kiến nghị khởi tố theo pháp luật tố tụng hình sự Việt Nam từ thực tiễn tỉnh Bình Định (Luận văn thạc sĩ)BT Tieng anh 6 UNIT 2Nguyên tắc phân hóa trách nhiệm hình sự đối với người dưới 18 tuổi phạm tội trong pháp luật hình sự Việt Nam (Luận văn thạc sĩ)Giáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtBÀI HOÀN CHỈNH TỔNG QUAN VỀ MẠNG XÃ HỘIMÔN TRUYỀN THÔNG MARKETING TÍCH HỢPTÁI CHẾ NHỰA VÀ QUẢN LÝ CHẤT THẢI Ở HOA KỲ