Báo cáo khoa học: Monomeric molten globule intermediate involved in the equilibrium unfolding of tetrameric duck d2-crystallin pdf

... promoting an increase in proopiomelanocortin and cocaine and amphetamine regulated transcript. Taken together, these findings provide a compelling argument for the role for malo- nyl-CoA in regulating ... and certain amino acids [16]. A linkage between fatty acid synthesis in the CNS and feeding behavior was uncovered with the finding that systemic or intracerebroventricular adminis...

Ngày tải lên: 14/02/2014, 22:20

... the meta- llation mechanisms of the individual domains, in the hope, initially, of simplifying the interpretation of the metallation details of the two-domain protein. The results presented here ... investigated the metal-binding reactivity of the isolated a domain of human metallothionein isoform 1a, with specific emphasis on resolving the debate concerning...

Ngày tải lên: 19/02/2014, 00:20

... were raised in rabbits against a GST-War1p fusion protein containing 294 amino acids of the C-terminal part of War1p (amino acids 650– 944) fused in- frame to the C-terminus of GST. The gene fusion ... DNA-binding zinc cluster at the N-terminus, whereas the acidic activation domain is usually present at the C-terminus. The mid- dle homology region (MHR) bridging the D...

Ngày tải lên: 19/02/2014, 00:20

... defining the set of items that have ever been the actor in a flight. Their definition is solely within NIKL using the QUA link [14], which is exactly the set of fillers of a slot. While having ... expressions in inten- sional logic. 3 4. Use of the Taxonomy in Janus By domain mode/we mean the set of axioms en- coded in NIKL regarding the constants. The...

Ngày tải lên: 21/02/2014, 20:20

... meanings). 2. the meaning of the rules (rule meanings). In Montague Grammar these meanings are ex- pressed in intensional logic. In the Rosetta system the meanings of rules and basic expressions ... If we combine this principle with the Isomorphy Principle, the main consequence is that the semantic derivation trees constitute the intermediate language and tha...

Ngày tải lên: 22/02/2014, 10:20

... examination of the polyubiquitination of mutant SOD1 using FRET may be useful for inves- tigating the details of the role of the ubiquitin–protea- some system in neurodegenerative diseases in ... analysis of HSP70–YFP in Huntingtin- 150Q–CFP inclusions revealed that HSP70 is mobile within the inclusion [20]. As the movement of HSP70 is significantly slower in t...

Ngày tải lên: 06/03/2014, 09:22

... inhi- bitor of growth protein 3 (ING3) PHD, which is another domain involved in chromatin binding and clearly more divergent (e-value 0.019) from DIDO and the other sequences. As the alignment ... from the other bran- ches, which was indeed predicted. The other main group, obtained 97% of the time in 20 740 explored trees, contained the DIDO PHD sequences clustered with...

Ngày tải lên: 07/03/2014, 21:20

... [41]. In the present study, most of the proteins from both EDTA-SM and WSMmigratedinthegelwithnodistinctpattern,leavinga dark continuous smear after silver staining (Fig. 4). No discrete individual ... acid-rich glycoproteins would be present both within the silk gel prior to mineralization and also as electron-dense patches at the surface of b-chitin. The presence of chitin...

Ngày tải lên: 21/02/2014, 01:21

... near the N- and C-termini of the linkers: this suggests that a mobile connection with both the catalytic domain and the binding module is required for the function of the nanomachine. Furthermore, ... spring, allowing the nanomachine (catalytic domain–linker–binding module) to crawl on the substrate surface. The possible functional implications of the linker primary...

Ngày tải lên: 14/02/2014, 18:20

... Yer- sinia, the increased synthesis of LcrV triggered by the activation of the system leads to the titration of LcrG, which binds LcrV in a 1 : 1 complex. In turn, this results in a release of the ... by the sug- gestion that pH sensing by Salmonella involves modi- fications in the assembly of the translocon, which affect the pH gradient within the needle,...

Ngày tải lên: 14/02/2014, 22:20