Báo cáo khoa học: Monomeric molten globule intermediate involved in the equilibrium unfolding of tetrameric duck d2-crystallin pdf
Tài liệu Báo cáo khoa học: Hypothalamic malonyl-CoA and CPT1c in the treatment of obesity pptx
... promoting an increase in proopiomelanocortin and cocaine and amphetamineregulated transcript. Taken together, these findingsprovide a compelling argument for the role for malo-nyl-CoA in regulating ... and certain amino acids [16].A linkage between fatty acid synthesis in the CNSand feeding behavior was uncovered with the findingthat systemic or intracerebroventricular administration of fatty ... needs to beexplored further. Other areas of the brain have alsobeen shown to regulate feeding via AMPK [35,36]. Of interest is the extensive use of fructose as asweetener in the human diet [37]....
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Tài liệu Báo cáo khoa học: Evidence for noncooperative metal binding to the a domain of human metallothionein ppt
... the meta-llation mechanisms of the individual domains, in the hope, initially, of simplifying the interpretation of the metallation details of the two-domain protein. The results presented here ... investigated the metal-binding reactivity of the isolated a domain of human metallothionein isoform 1a, with specificemphasis on resolving the debate concerning the cooperative nature of the metal-binding ... completeinterpretation of the previous data in terms of non-cooperative, domain-specific metal binding.ResultsInvestigation into the metal-binding mechanism of the isolated a domain was carried...
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Tài liệu Báo cáo khoa học: A genetic screen identifies mutations in the yeastWAR1 gene, linking transcription factor phosphorylation to weak-acid stress adaptation docx
... were raised in rabbitsagainst a GST-War1p fusion protein containing 294 aminoacids of the C-terminal part of War1p (amino acids 650–944) fused in- frame to the C-terminus of GST. The genefusion ... DNA-binding zinccluster at the N-terminus, whereas the acidic activationdomain is usually present at the C-terminus. The mid-dle homology region (MHR) bridging the DNA-bind-ing and the activation ... expression of the C-terminal 294 amino acids of WAR1 fused in- frameto the C-terminus of GST. Escherichia coli strain DH5aharboring pCG1950 was grown on 37 °CtoanA600 of 0.5.Expression of the GST-War1p...
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Tài liệu Báo cáo khoa học: "A HYBRID APPROACH TO REPRESENTATION IN THE JANUS NATURAL LANGUAGE PROCESSOR" pot
... defining the set of items that have ever been the actor in a flight. Their definition is solely within NIKL using the QUA link [14], which is exactly the set of fillers of a slot. While having ... expressions in inten- sional logic. 3 4. Use of the Taxonomy in Janus By domain mode/we mean the set of axioms en- coded in NIKL regarding the constants. The domain model serves several purposes in ... all of the definitions of approximately 200 items from the base vocabulary using the defini. tJons of those vocabulary items themselves in the dictionary. In this attempt, we encountered the...
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Tài liệu Báo cáo khoa học: "Subgrammars, Rule Classes and Control in the Rosetta Translation System" ppt
... meanings). 2. the meaning of the rules (rule meanings). In Montague Grammar these meanings are ex- pressed in intensional logic. In the Rosetta system the meanings of rules and basic expressions ... If we combine this principle with the Isomorphy Principle, the main consequence is that the semantic derivation trees constitute the intermediate language and that the attuning of the grammars ... Compositionalit¥ Principle." The meaning of an expression is a function of the meaning of its parts and the way in which they are syntactically combined. This principle was adopted...
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Báo cáo khoa học: Amyloid oligomers: dynamics and toxicity in the cytosol and nucleus ppt
... examination of the polyubiquitination of mutant SOD1 using FRET may be useful for inves-tigating the details of the role of the ubiquitin–protea-some system in neurodegenerative diseases in ... analysis of HSP70–YFP in Huntingtin-150Q–CFP inclusions revealed that HSP70 is mobilewithin the inclusion [20]. As the movement of HSP70 issignificantly slower in the inclusion than in the cytosol,HSP70 ... mutant proteins results in increased mis-folding of normal proteins and further enhancement of co-aggregation. In this state, the degradation of mis-folded proteins is diminished by their insolubility,...
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Báo cáo khoa học: Death inducer obliterator protein 1 in the context of DNA regulation Sequence analyses of distant homologues point to a novel functional role docx
... inhi-bitor of growth protein 3 (ING3) PHD, which isanother domain involved in chromatin binding andclearly more divergent (e-value 0.019) from DIDO and the other sequences. As the alignment ... from the other bran-ches, which was indeed predicted. The other maingroup, obtained 97% of the time in 20 740 exploredtrees, contained the DIDO PHD sequences clusteredwith the PHF and the ... analyses The localization of the DIDO1 gene in the context of chromatin stability was addressed experimentally.Although the experiments conducted were preliminary,they indicated the involvement of...
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Tài liệu Báo cáo Y học: Soluble silk-like organic matrix in the nacreous layer of the bivalve Pinctada maxima A new insight in the biomineralization field pptx
... [41]. In the presentstudy, most of the proteins from both EDTA-SM andWSMmigratedinthegelwithnodistinctpattern,leavingadark continuous smear after silver staining (Fig. 4). Nodiscrete individual ... acid-richglycoproteins would be present both within the silk gel priorto mineralization and also as electron-dense patches at the surface of b-chitin. The presence of chitin combined with the silk-fibroin-like ... to the WSM, andconsequently the EDTA-IM. Hydroxyproline, hydroxy-lysine and phosphoserine were not detected in WSM, WIM,EDTA-SM and EDTA-IM. The comparison of the amino acid composition of the main...
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Tài liệu Báo cáo khoa học: How to remain nonfolded and pliable: the linkers in modular a-amylases as a case study ppt
... near the N- and C-termini of the linkers: this suggests thata mobile connection with both the catalytic domainand the binding module is required for the function of the nanomachine. Furthermore, ... spring, allowing the nanomachine (catalytic domain–linker–bindingmodule) to crawl on the substrate surface. The possiblefunctional implications of the linker primary structuresare presented in ... restrict the available dihedral angles between the participatingTable 1. Amino acid frequencies (%) in a-amylase linkers, in a set of globular proteins, in the Swiss-Prot databank and in intrinsicallyunstructured...
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Tài liệu Báo cáo khoa học: Membrane targeting and pore formation by the type III secretion system translocon pdf
... Yer-sinia, the increased synthesis of LcrV triggered by the activation of the system leads to the titration of LcrG,which binds LcrV in a 1 : 1 complex. In turn, thisresults in a release of the ... by the sug-gestion that pH sensing by Salmonella involves modi-fications in the assembly of the translocon, whichaffect the pH gradient within the needle, sending sig-nals to the base of the ... characterization of the proteins involved in translocon formation, as well as their participation in the modi-fication of intracellular signalling pathways upon infection. Models of tran-slocon...
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Từ khóa: Báo cáo thực tập tại nhà thuốc tại Thành phố Hồ Chí Minh năm 2018Một số giải pháp nâng cao chất lượng streaming thích ứng video trên nền giao thức HTTPNghiên cứu vật liệu biến hóa (metamaterials) hấp thụ sóng điện tử ở vùng tần số THzBiện pháp quản lý hoạt động dạy hát xoan trong trường trung học cơ sở huyện lâm thao, phú thọGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitĐỒ ÁN NGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWANNGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWAN SLIDETrả hồ sơ điều tra bổ sung đối với các tội xâm phạm sở hữu có tính chất chiếm đoạt theo pháp luật Tố tụng hình sự Việt Nam từ thực tiễn thành phố Hồ Chí Minh (Luận văn thạc sĩ)Định tội danh từ thực tiễn huyện Cần Giuộc, tỉnh Long An (Luận văn thạc sĩ)Tìm hiểu công cụ đánh giá hệ thống đảm bảo an toàn hệ thống thông tinThiết kế và chế tạo mô hình biến tần (inverter) cho máy điều hòa không khíSở hữu ruộng đất và kinh tế nông nghiệp châu ôn (lạng sơn) nửa đầu thế kỷ XIXKiểm sát việc giải quyết tố giác, tin báo về tội phạm và kiến nghị khởi tố theo pháp luật tố tụng hình sự Việt Nam từ thực tiễn tỉnh Bình Định (Luận văn thạc sĩ)Quản lý nợ xấu tại Agribank chi nhánh huyện Phù Yên, tỉnh Sơn La (Luận văn thạc sĩ)chuong 1 tong quan quan tri rui roNguyên tắc phân hóa trách nhiệm hình sự đối với người dưới 18 tuổi phạm tội trong pháp luật hình sự Việt Nam (Luận văn thạc sĩ)Giáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtChiến lược marketing tại ngân hàng Agribank chi nhánh Sài Gòn từ 2013-2015Đổi mới quản lý tài chính trong hoạt động khoa học xã hội trường hợp viện hàn lâm khoa học xã hội việt namTÁI CHẾ NHỰA VÀ QUẢN LÝ CHẤT THẢI Ở HOA KỲ