Báo cáo khoa học: Unique features of the hemoglobin system of the Antarctic notothenioid fish Gobionotothen gibberifrons ppt

... Unique features of the hemoglobin system of the Antarctic notothenioid fish Gobionotothen gibberifrons Panagiotis Marinakis, Maurizio Tamburrini, Vito Carratore and Guido di Prisco Institute of ... Naples, Italy ThehemolysateoftheAntarcticteleostGobionotothen gibberifrons (family Nototheniidae) contains two hemoglo- bins (Hb 1 and Hb 2). The concentration of...

Ngày tải lên: 08/03/2014, 08:20

... side of the heme. In DmHO, Thr35 corresponding to Thr21 of HO-1 is conserved, but the other two amino acid residues are not. The crystal structure of HO-1 also shows that the backbone atoms of the ... Ascorbate was omitted from the control system. Reduction was initiated by the addition of ascorbate. Other conditions were the same as those for the NADPH/DmDCPR sy...

Ngày tải lên: 19/02/2014, 12:20

... is capable of reducing the level of fructose 2,6-P 2 inde- pendent of the phosphorylation state of iPFK-2. Reducing the level of fructose 2,6-P 2 and thus the activity of PFK-1 improves the supply of ... the activity of the enzyme by x% results in a significant change of the pathway flux by at least 0.5x% (whether 0.5x% or higher is a matter of convention)....

Ngày tải lên: 14/03/2014, 23:20

... region. Effect of mutations in the C-terminal region of the RmInt1 IEP on RNA splicing in vivo We constructed a series of mutants to identify the functional features of the C-terminal region of the RmInt1 ... resi- due at the N-terminus of a-helix a4, the domain X contains the conserved amino acid residues HKXRA (RmInt1 residues 388–392) carrying a stretch of b...

Ngày tải lên: 15/03/2014, 09:20

... that the stoichiometries of the Hg-bMT species become dependent on t and X after t he forma tion of Hg 7 -bMT. Comparison of the three sets of CD data indicates that the degree of chirality of the ... provide information on the binding of Hg(II) to the corresponding apo-MT form [23]. In a ddition, compar- ison of the two sets of data gives an indication of...

Ngày tải lên: 16/03/2014, 18:20

... (where the patient received the drug). The intercepted errors were scored separately on the basis of their possible impact on the patient, if the prescription had been administered as prescribed. The ... blinded to the prescribing system; this could have introduced the potential for bias in the results and is a limitation of the study. Medical errors are among the...

Ngày tải lên: 25/10/2012, 10:39

... characterization of these compounds is growing and may result in the synthesis of specific inhibitors based on the structure of the pathogen siderophore [16]. A promising approach for the isolation of secondary metabolites, ... derivatization-based elucidation of the overall stereochemistry. Further- more, the functional properties of erythrochelin acting as an iron-che...

Ngày tải lên: 16/02/2014, 09:20

... [8,9]. One of the interesting features of the plant PSs is the presence of a conserved 24 residue insertion in the sequence [9]. This sequence of amino acids, which is missing in the sequence of bacterial ... pantothe- nate from low amounts of pantoate [9]. Here, we report the results of the structural studies of the panto- ate-bound form of the N-termina...

Ngày tải lên: 16/02/2014, 09:20

... which does not appear to be the native condition for C-peptide [13]. The structural features of the aggre- gation properties of the amyloid precursor protein, as well as of the opioid peptide dynorphin, ... of approximately 16 A ˚ , which is in agreement with the results of the NMR. The addition of SDS to the C-peptide sample leads to formation of larger obje...

Ngày tải lên: 18/02/2014, 04:20

... a molecular mass of 16 309.7 Da, but this matched none of the DNA-predicted proteins. MS ⁄ MS of these ions gave the C-terminal sequence of Fig. 5. These and all other peaks of that spectrum ... substitution; MS ⁄ MS will then show the substituent positions of dif- ferent isomers. A problem for MS ⁄ MS of either the peptides for the bottom-up approach or of the pro...

Ngày tải lên: 18/02/2014, 16:20