Báo cáo khoa học: Modified merozoite surface protein-1 peptides with short alpha helical regions are associated with inducing protection against malaria docx

... Modified merozoite surface protein-1 peptides with short alpha helical regions are associated with inducing protection against malaria Mary H. Torres 1 *, Luz M. ... de Colombia, Bogota ´ , Colombia The merozoite surface protein-1 represents a prime candi- date for development of a malaria vaccine. Merozoite sur- face protein-1 has been shown to de...

Ngày tải lên: 08/03/2014, 08:20

... results are ob- tained with a rather high DL, that is 10 (only KRS improves with a lower DL). However, with modified distortion, the best results according to all metrics are obtained with a DL ... re- orderings per sequence. With L×F we obtain sev- eral improvements, but it’s with A×A that we are able to beat the baseline according to all metrics. BLEU and METEOR improveme...

Ngày tải lên: 19/02/2014, 19:20

... synthesis with modified lock-docking oligo(dT) and 5¢-cap oligonucleotide primer Prepare total RNA using Trizol RNA isolation reagent (Invitrogen). Synthesize double-stranded cDNAs using the modified ... 5¢-CCAGACACTATGCTCATA-3¢ UP-II: 5¢-CACTATGCTCATACGACGCAGT-3 ¢ Scheme 3 – modified reverse SAGE (rSAGE) method Step 1. cDNA synthesis with modified oligo(dT) primer Prepare total RNA a...

Ngày tải lên: 07/03/2014, 00:20

... detergent-resistant membranes; malaria; mer- ozoite surface protein; O-GlcNAc modification; vesicles. In the blood-stage forms of the malarial parasite Plasmodium falciparum, the merozoite surface protein 1 ... reticulocyte lysates [32], as well as membrane -associated. Most O-GlcNAc -modified proteins are indeed cytoplasmic or nuclear [15], but are also found at the cell surface...

Ngày tải lên: 08/03/2014, 08:20

... a modified colorimetric assay The modified colorimetric assay developed in this work was used to screen for uricase mutant genes derived from the thermophilic bacterium Bacillus subtilis. A modified ... to screen for uricase activity using a modified fast colorimetric 96-well plate assay. Plates were incubated with shaking at 37 °C, for a maximum of 18 h, with IPTG to induce the expre...

Ngày tải lên: 23/03/2014, 12:20

... starmaker are orthologous genes that are highly diverged, so the identity of their sequences is low and orthologs cannot be found, or (ii) they are different but similar genes that are conserved ... the crystal forma- tion when they are applied to crystal induction systems with framework organic substrates [4–7], indicating that such proteins may interact with the framework mole...

Ngày tải lên: 18/02/2014, 17:20

... z à i Þ=z à i , with i ¼ 1,. ,9, obtained by integrating the nine-dimensional PTS model with MATLAB’s ode23s ODE suite (solid curves) and with the time measured in milliseconds. The dashed curves are the ... we denote by  y, with dimð  yÞ¼n y ¼ n À n x ] are at quasi-steady-state with respect to the instanta- neous values of the remaining state variables [which we denote by ...

Ngày tải lên: 18/02/2014, 06:20

... isomerohydrolase compared with that from rod-dominant species. J Biol Chem 283, 8110–8117. 23 Yethon JA, Epand RF, Leber B, Epand RM & Andrews DW (2003) Interaction with a membrane surface triggers ... in Bax normally associated with induction of apoptosis. J Biol Chem 278, 48935–48941. 24 Moiseyev G, Crouch RK, Goletz P, Oatis J Jr, Redmond TM & Ma JX (2003) Retinyl esters...

Ngày tải lên: 18/02/2014, 08:20

... with F and ending with E (or vice versa) to obtain recurring source-target patterns. At runtime, we can submit E as query, request specifically for target-language web-pages. With these surface ... engine with the language option set to the target language to obtain a set of summaries. (2) Matching patterns against summaries. The surface patterns P learned in the training...

Ngày tải lên: 20/02/2014, 15:20

... X) = if all syntactic redexes in below are reduced then return else pick a formula redex in that is unreduced, with in add to where are new segment terms with fresh variables add to for all solve ... nondeterminis- tic distribution rules, with , this set can be non-singleton; but the rules we are going to intro- duce are all deterministic propagation rules (with ). 6.2 Solving...

Ngày tải lên: 23/03/2014, 19:20