Báo cáo khoa học: Signaling events mediating activation of brain ethanolamine plasmalogen hydrolysis by ceramide pot
Báo cáo khoa học: Signaling events mediating activation of brain ethanolamine plasmalogen hydrolysis by ceramide pot
... E. Latorre et al.(Eur. J. Biochem. 270) Ó FEBS 2003
Signaling events mediating activation of brain ethanolamine
plasmalogen hydrolysis by ceramide
Eduardo Latorre
1
, M. Pilar Collado
1
, Inmaculada ... that activation of hydrolysis of
Etn phospholipids by PLA
2
results from the covalent
modification of the enzyme [38].
In an attempt to establish the potential...
Báo cáo khoa học: Insights into the activation of brain serine racemase by the multi-PDZ domain glutamate receptor interacting protein, divalent cations and ATP ppt
... binding
results in activation of brain SR. J Biol Chem 277,
27782–27792.
10 Neidle A & Dunlop DS (2002) Allosteric regulation of
mouse brain SR. Neurochem Res 27, 1719–1724.
Activation of brain SR by GRIP, ... of a two-fold molar
excess of the PDZ6 domain of GRIP under different assay condi-
tions. Data are representative of three independent experiments.
F. Baum...
Báo cáo khoa học: Stage-specific activation of MIG-17⁄ADAMTS controls cell migration in Caenorhabditis elegans docx
... proform localizes
to the surfaces of the gonad, intestine and hypodermis
corresponding to the basement membranes [17]. To
determine the sites of activation of MIG-17 and tissue
distribution of ... including both the proform
and the activated form, was immunoblotted
(right lane). Single asterisk, proform of MIG-
17–GFP; double asterisk, activated form of
MIG-17–GFP; arrow, profor...
Tài liệu Báo cáo khoa học: Mixed-type noncompetitive inhibition of anthrax lethal factor protease by aminoglycosides ppt
... exported from the softmax pro
software (Molecular Devices) and analyzed by using the
software batchki (BioKin Ltd, Pullman, WA, USA).
P. Kuzmic et al. Inhibition of lethal factor protease by aminoglycosides
FEBS ... existence of multiple enzyme–inhibitor binding
sites or the involvement of multiple structural binding modes at the same
site. Quantitative analysis of the ionic stren...
Tài liệu Báo cáo khoa học: DNA strand exchange activity of rice recombinase OsDmc1 monitored by fluorescence resonance energy transfer and the role of ATP hydrolysis pptx
... l
M of OsDmc1 in absence of ATP; (2) with 1.25 lM of
OsDmc1 in presence of 2.0 m
M of AMP-PNP; (3) with 1.25 lM
of OsDmc1 in presence of 2.0 mM ATP-c-S; (4) with 1.25 lM of
OsDmc1 in presence of ... exchange
events where ATP hydrolysis seems to critically decide the rates of the reac-
tion system. These studies open up new facets of a plant recombinase func-
tion in...
Báo cáo khoa học: PRDM1/Blimp1 downregulates expression of germinal center genes LMO2 and HGAL pot
... exchange rate of RhoA and
results in inhibition of lymphocyte and lymphoma cell
motility, induction of transcriptional activation
by serum response factor and amplification of RhoA
transforming potential ... lL of transfection mix (1 lL of SiPort, 75 ng of
pRL-TK, 1.25 lg of the luciferase reporter plasmid, and
1 lg of the PRDM1a expression plasmid or control
pCDNA3.1 per...
Báo cáo khoa học: Flexible nets The roles of intrinsic disorder in protein interaction networks potx
... mobility of this molecule [84] also sug-
gests a high content of extended structure. Figure 2A
compares the results of PONDRÒ analysis by two pre-
dictors of intrinsic disorder, firstly, a predictor of ... (as esti-
mated by a method suggested in [130]). The binding of
p27
Kip1
to Cdk2 leading to the inhibition of kinase
activity is much slower and is accompanied by the fol...
Báo cáo khoa học: Sub-zero temperature inactivation of carboxypeptidase Y under high hydrostatic pressure pot
... study,
detailed molecular events in the pressure-induced cold
inactivation of CPY are described.
Action of reducing agent which reveals site(s) of cold
inactivation
The action of reducing agent was ... HCl
concentration of 1
M
or above.
Effect of SDS upon cold inactivation of CPY under high
pressure
CPY was incubated at )10 °C for 30 min under 400 MPa
in the presence of vari...
Báo cáo khoa học: Untangling the folding mechanism of the 52-knotted protein UCH-L3 potx
... resistant to unfolding
and thereby minimize the risk of degradation by the
26S proteasome [3,25].
Given the current lack of knowledge regarding both
the stability and folding of the 5
2
-knotted ubiquitin
hydrolases, ... and
indicative of the population of the hyperfluorescent
intermediates decaying as the population of the native
state species increased.
The folding pathway of...
Báo cáo khoa học: Cytokinin-induced structural adaptability of a Lupinus luteus PR-10 protein potx
... (maximum deviation of 9.3 A
˚
for the
Ca atoms of Gly89) and loop L9 (maximum deviation
of 4.7 A
˚
at Gly123). The conformational change of
loop L9 is evidently caused by the presence of the
sodium ... Poland
3 Department of Protein Engineering, Faculty of Biotechnology, University of Wroclaw, Poland
4 Institute of Plant Genetics, Polish Academy of Sciences, Poznan, Pola...