... experiments were performed to determine the influence of the introduced mutations on the localization of the receptor proteins and the degree of their colocalization. Figure 2A,B shows HEK293 cells ... their interactions with the appropriate a subunits of G protein, further confirm that the use of advanced fluorescence techni- ques does indeed allow for the observatio...
Ngày tải lên: 07/03/2014, 03:20
... publication On the Origin of Species by Means of Natural Selec- tion, or the Preservation of Favoured Races in the Struggle for Life [1], Darwin’s theory of evolution, in which natural selection acting ... until their rediscovery at the turn of the 20th century) nor of what the physical basis underlying variation within populations might be. Since the discovery...
Ngày tải lên: 18/02/2014, 11:20
Tài liệu Báo cáo khóa học: Determination by electrospray mass spectrometry and 1H-NMR spectroscopy of primary structures of variously fucosylated neutral oligosaccharides based on the iso-lacto-N-octaose core doc
... that contains this difucosylation on the 6-branch [17]. Thus, TFiLNO has the following structure: MFiLNO. The monosaccharide composition of MFiLNO was shown by methylation analysis to consist of ... oligosac- charides are considered to play a part in the inhibition of bacterial adhesion to epithelial surfaces, as they are able to mimic the binding epitope of the epitheli...
Ngày tải lên: 19/02/2014, 12:20
Báo cáo y học: "Update on the treatment of ocular toxoplasmosis"
... lesion within the vascular arcades of the posterior pole (zone 1) b) the presence of a lesion in the proximity of the optic nerve or the macula c) or a severe inflammatory reaction within the ... infection. Disease evolution depends on many factors: the immune response of the host, the virulence of the parasite and environmental factors and ocular toxopl...
Ngày tải lên: 03/11/2012, 11:01
Tài liệu Báo cáo khoa học: Hepatic stimulator substance mitigates hepatic cell injury through suppression of the mitochondrial permeability transition pdf
... from the generation of an electro- chemical gradient across the IM forms the basis of the IM w m . During cell death, MP often increases, allow- ing for the release of soluble proteins. The only mechanism ... the activation of mitochondria-dependent apoptosis [12], the assembly of the apoptosome. Upon formation of this complex, caspase-9 acquires the ability...
Ngày tải lên: 16/02/2014, 09:20
Tài liệu Báo cáo khoa học: Arabidopsis thaliana BTB⁄ POZ-MATH proteins interact with members of the ERF⁄AP2 transcription factor family ppt
... interaction requires a complete MATH domain and the N-terminal region of RAP2.4 The use of a truncated version of BPM1 in the Y2H screens demonstrated that the BTB domain is not involved in the assembly ... lines, we saw GUS expression in the vascu- lar tissue of cotyledons and mature leaves, whereas, in the flowers, the anthers, connectives and filaments and the base...
Ngày tải lên: 18/02/2014, 06:20
Tài liệu Báo cáo khoa học: Evidence that the assembly of the yeast cytochrome bc1 complex involves the formation of a large core structure in the inner mitochondrial membrane pdf
... bc 1 sub-complex, but the presence of only one of these two subunits does not substitute for the other. After the addition of ISP, the binding of the last subunit (i.e. Qcr10p) finally occurs. These find- ings ... too small to explain the dimerization of the bc 1 complex at this stage (i.e. just after the addition of ISP and Qcr10p). On the other hand, in the t...
Ngày tải lên: 18/02/2014, 08:20
Tài liệu Báo cáo khoa học: Studies on structural and functional divergence among seven WhiB proteins of Mycobacterium tuberculosis H37Rv pdf
... because of changes in the chemical environment around the iron–sulfur cluster, the partial destruction of the cluster or its con- version to other forms. In order to investigate the probable reason(s) ... significantly low- ered the rate of disintegration of the iron–sulfur cluster in each of the WhiB proteins (Fig. 3C,D). Therefore, disassembly of the iron–sulf...
Ngày tải lên: 18/02/2014, 12:20
Tài liệu Báo cáo khoa học: Looking for the ancestry of the heavy-chain subunits of heteromeric amino acid transporters rBAT and 4F2hc within the GH13 a-amylase family ppt
... analysed using the selecton tool [38] at http://selecton.tau.ac.il/. The ratio between nonsynonymous (Ka) and synony- mous (Ks) substitutions was calculated for every codon using the default M8 codon-substitution ... (d) sequences contain between four and seven conserved sequence regions (CSRs) covering mainly the b-strands of the catalytic TIM barrel [3,11–13]. Of the three G...
Ngày tải lên: 18/02/2014, 13:20
Tài liệu Báo cáo khoa học: Acetylcholinesterase from the invertebrate Ciona intestinalis is capable of assembling into asymmetric forms when co-expressed with vertebrate collagenic tail peptide doc
... iden- tify the nature of the enzyme and provide additional information about the evolution of the ChEs, including the origins of the acyl pocket, the T exon, and the asymmetric forms of ChE in the vertebrates. Results The ... tetramers of the asymmetric forms. The A 12 form consists of three such tetramers attached to the triple-stranded helix of ColQ....
Ngày tải lên: 18/02/2014, 17:20