... ich- thyosiform erythroderma (NCIE, in layman’s terms translating as a nonblistering, inherited, scaly red skin). An independent study later extended these find- ings following the identification of 17 ... isomerase (hepoxilin synthase) The genetic findings concerning 12R-LOX and eLOX3 mutations in ichthyosis are intriguing from the bio- chemical point of view, partly because the eLOX3 pro-...
Ngày tải lên: 07/03/2014, 09:20
... are considering basing our re-ranking on the informa- tion held in the dialogue information state, knowl- edge of what is going on in the graphical interface and on dialogue moves in the list ... the domain adapted newspaper Corpus. 3.1 Interpolating the GSLC corpus and the MP3 corpus A technique used in language modelling to com- bine different SLMs is linear interpolation (Jelinek &...
Ngày tải lên: 22/02/2014, 02:20
Báo cáo khoa học: "Veterinary decision making in relation to metritis - a qualitative approach to understand the background for variation and bias in veterinary medical records"
... followed their own definitions of different scoring values, such as excluding certain scores (see examples in table 1). They find the def- initions incorrect. If the veterinarian strictly follows ... observations regarding Table 1: Table of metritis score definitions and examples of present usage in practice. Scores Clinical signs - vaginal examination Cases Practical scoring Decision mak...
Ngày tải lên: 25/10/2012, 10:45
Tài liệu Báo cáo khoa học: An alternative isomerohydrolase in the retinal Muller cells of a cone-dominant species doc
... GS staining (B3), and 4¢,6-diamidino-2-phenylindole (DAPI) staining (B4), respectively. (B5-8) High magnification images of the boxed area in (B4) showing RPE65c staining (B5), GS staining (B6), ... enzymes and retinoid-binding pro- teins between photoreceptors and retinal pigment epi- thelium (RPE); it is essential for maintaining normal vision [3,4]. The key step in the retinoid visual c...
Ngày tải lên: 14/02/2014, 14:20
Tài liệu Báo cáo khoa học: Applications and trends in systems biology in biochemistry docx
... protein kinase; MCF, macrophare chemotactic factor; MCIP, modulatory calcineurin-interact- ing protein; MDCK, Madin Darby canine kidney; MEF, mouse embryonic fibroblast; MEK, MAP kinase/ERK kinase; ... glycogen synthase) is insufficient to accurately explain insulin-stimulated changes in the concentration of intracellular species and partitioning of glucose disposal in skeletal muscle. Insu...
Ngày tải lên: 14/02/2014, 14:20
Tài liệu Báo cáo khoa học: TEC family kinases in health and disease – loss-of-function of BTK and ITK and the gain-of-function fusions ITK–SYK and BTK–SYK pptx
... signaling proteins carrying domains also found in BTK. In 2009, an inactivating mutation in the ITK gene was shown to cause susceptibility to lethal Epstein–Barr virus infec- tion. Both kinases ... have anti -in ammatory activity. Since 2006, several patients carry- ing a fusion protein, originating from a translocation joining genes encoding the kinases ITK and spleen tyrosine kinase (...
Ngày tải lên: 14/02/2014, 18:20
Tài liệu Báo cáo khoa học: RMI1 deficiency in mice protects from diet and genetic-induced obesity pptx
... observable. Interestingly, the RMI1 mRNA level increased signifi- cantly in the liver and intra-abdominal fat of the obese phenotype mice; however, that in the skeletal muscle did not increase, and that in ... the Bloom’s syndrome gene helicase complex that maintains genome integrity and activates cell-cycle checkpoint machinery. Interestingly, diet-induced expression of E2F8 mRNA, which...
Ngày tải lên: 16/02/2014, 09:20
Tài liệu Báo cáo khoa học: SREBPs: SREBP function in glia–neuron interactions pdf
... myelin protein-22, myelin asso- ciated glycoprotein (MAG) and myelin basic protein, but no myelin-specific lipids. Nevertheless, whereas all major lipid classes are present in myelin, as in other membranes, ... transit of albumin, a fatty acid-binding protein present in the developing brain, into the astrocytic endoplasmic reticulum compartment. This transit of albumin correlated with in...
Ngày tải lên: 18/02/2014, 13:20
Tài liệu Báo cáo khoa học: Transcriptional upregulation of inflammatory cytokines in human intestinal epithelial cells following Vibrio cholerae infection pptx
... the toxin-producing strain. Among the proinflammatory cytokines, GM-CSF expression was induced substantially in all the strains, the increase in expression being maximum following N16961 infec- tion ... line Int407 upon Vibrio cholerae infection. These proinflammatory cytokines also showed increased expression in T84 cells, except for interleukin-6, whereas a striking dissimilarity in c...
Ngày tải lên: 18/02/2014, 16:20
Tài liệu Báo cáo khoa học: Metabolic gene switching in the murine female heart parallels enhanced mitochondrial respiratory function in response to oxidative stress pdf
... 2007) doi:10.1111/j.1742-4658.2007.06051.x The mechanisms underlying increased cardioprotection in younger female mice are unclear. We hypothesized that serine-threonine protein kinase (protein kinase B; Akt) triggers a metabolic ... insights into this interesting question. Conclusions In summary, we have identified a novel metabolic gene switch (decrease in fatty acid utilization, incre...
Ngày tải lên: 18/02/2014, 16:20