Báo cáo khoa học: Sequences downstream of the transcription initiation site are important for proper initiation and regulation of mouse ribonucleotide reductase R2 gene transcription ppt
Báo cáo khoa học: Sequences downstream of the transcription initiation site are important for proper initiation and regulation of mouse ribonucleotide reductase R2 gene transcription ppt
... 270) 1801 Sequences downstream of the transcription initiation site are important for proper initiation and regulation of mouse ribonucleotide reductase R2 gene transcription Irina Kotova, Anna ... the mouse ribonucleotide reductase R2 TATA-box and sequences downstream of it for their function in transcription from the R2 pro...
Ngày tải lên: 08/03/2014, 02:20
Báo cáo khoa học: NF-jB regulates the transcription of protein tyrosine kinase Tec pdf
... binding sites are indicated, and the known PU.1 and SP1 binding sites are also shown. (B) Schematic representation showing the potential NF-jB binding sites in human and mouse Tec promoters. (C) Transcriptional ... [33] and p-matchÔ software [34]. The scan results indicated two putative NF-jB binding sites in the mouse Tec promoter (Fig. 1A). To further determine the...
Ngày tải lên: 07/03/2014, 00:20
Báo cáo khoa học: Cellular refractoriness to the heat-stable enterotoxin peptide is associated with alterations in levels of the differentially glycosylated forms of guanylyl cyclase C pdf
... streptavidin-peroxidase (Fig. 5C). Therefore, there is a specific down -regulation of the 145 kDa form of GC-C on prolonged ligand treatment, indicating that only the ligand- responsive form of the receptor is perhaps ... reappearance of the 145 kDa form following removal of ST peptide was a consequence of further glycosylation of the ER-associated 130 kDa form, and...
Ngày tải lên: 08/03/2014, 08:20
Tài liệu Báo cáo khoa học: Fra-1 targets the AP-1 site/2G single nucleotide polymorphism (ETS site) in the MMP-1 promoter docx
... the MAPK pathway, ERK 1/2, targets the 2G SNP at )1607 bp and theadjacentAP-1siteat)1602 bp. Activation and/ or production of transcription factors binding to these sites are responsible for the ... PD098059 (Fig. 3A). The two bands in Fig. 3A represent the phosphorylated protein (upper band) and the nonphosphorylated form (lower band) of Fra-1. Both forms of the...
Ngày tải lên: 21/02/2014, 00:20
Báo cáo khoa học: "Jointly optimizing a two-step conditional random field model for machine transliteration and its fast decoding algorithm" pdf
... the best and the second best candidates; on the other hand, even if all the remaining probabilities are added to the second best candidate, it still cannot overturn the top candidate. The mathematical ... C 0 is the current character, C −1 and C 1 de- note the previous and next characters, and C −2 and C 2 are the characters located two positions to the lef...
Ngày tải lên: 17/03/2014, 00:20
Báo cáo khoa học: Bacterial b-peptidyl aminopeptidases with unique substrate specificities for b-oligopeptides and mixed b,a-oligopeptides pptx
... activities of the two BapA enzymes for the first five peptides were quantified by HPLC of the residual substrate; the reactions of the other substrates were analyzed by measuring the formation of the dipeptide ... acids are marked in black and similar amino acids are marked in gray. The cleavage sites of the proteins are marked with an arrow. The signal s...
Ngày tải lên: 30/03/2014, 10:20
Báo cáo khoa học: Sequences and structural organization of phospholipase A2 genes from Vipera aspis aspis, V. aspis zinnikeri and Vipera berus berus venom Identification of the origin of a new viper population based on ammodytin I1 heterogeneity docx
... 4 and the 5¢ part of exon 5 encode the mature protein; exon 1 encodes the 5¢-UTR, and exon 2 and part of exon 3 encode the signal peptide. The 110 nucleotides at the 3¢ end of exon 5 encode the ... the other PLA2 genes (Table 3). The ammodytoxin C, ammo- dytins I1 and I2 and ammodytin L genes of V. am. ammo- dytes, the VP7 and VP8 genes of V. palaesti...
Ngày tải lên: 17/03/2014, 03:20
Tài liệu Báo cáo khoa học: Dmrt1 genes at the crossroads: a widespread and central class of sexual development factors in fish pdf
... with the discovery of a dmrt1 homologue on the Y chromosome of the fish medaka (Oryzias latipes). This Y-chromosomal gene is the product of a gene duplication of the autosomal dmrt1a gene and was ... birds, mammals and corals is the dmrt gene family [5]. The prototype members of this group of factors are the Drosophila doublesex (dsx) and Caenor- hab...
Ngày tải lên: 14/02/2014, 19:20
Tài liệu Báo cáo khoa học: Nucleolin/C23 mediates the antiapoptotic effect of heat shock protein 70 during oxidative stress pptx
... Institutional Animal Care and Use Committee of the Center South Uni- versity, and were carried out in accordance with the National Institutes of Health Guide for the Care and Use of Laboratory Animals. All efforts ... lost. Taken together, our results demonstrate an impor- tant relationship among the regulation of nucleo- lin ⁄ C23, the activation of caspase-3 a...
Ngày tải lên: 16/02/2014, 09:20
Tài liệu Báo cáo khoa học: MicroRNA-23a promotes the growth of gastric adenocarcinoma cell line MGC803 and downregulates interleukin-6 receptor pdf
... with the first potential binding site of the IL6R mRNA 3¢ UTR. (A) The three EGFP reporter vectors bear- ing mutations of the miR-23a seed region binding site are shown. The arrows indicate the ... containing the mutations of the miR-23a binding site (Fig. 4A). It was shown that miR-23a ASO or pcDNA3 ⁄ pri-23a did not affect the intensity of EGFP fluorescence i...
Ngày tải lên: 18/02/2014, 04:20