Báo cáo khoa học: "The Modulation of Cooperation and Emotion in Dialogue: The REC Corpus" pdf

... Proceedings of the ACL-IJCNLP 2009 Student Research Workshop, pages 81–87,Suntec, Singapore, 4 August 2009.c2009 ACL and AFNLP The Modulation of Cooperation and Emotion in Dialogue: The REC ... annotation of the so-called “blended” emotions and their recognition. Usually, there is a low agreement among raters in annotating emotions and, surprisingly, emo-tion recognition is higher in a ... are pointed out during the recordings by psychophysiologi-cal indexes (ElectroCardioGram, and Galvanic Skin Conductance). From the output values of these indexes a general recognition of each...

Tài liệu Báo cáo khoa học: Abstract Integration of Metabolism and Survival PP-1 The metabolic switch in liver methionine metabolism pptx

... content in the liver were low in the control group, higher in the antioxidant-supplemented group and the highest in the alco-holic group. Interestingly, the level of total thiol in the liver of antioxidant-supplemented ... polypeptideregulates the RecA loading activity of RecBCD. We ligated twopolypeptides, RecB and RecD, which are the slow and fast heli-cases of the enzyme, by an insertion of three amino acid and searched whether ... charac-teristic of the DNA. We determined a direct correlation betweenexonuclease activity of APE1 and the thermal stability of DNAduplexes. The efﬁciency of the removal and the thermal stability of DNA...

Tài liệu Báo cáo khoa học: Allosteric modulation of myristate and Mn(III)heme binding to human serum albumin Optical and NMR spectroscopy characterization pptx

... albu-min conformation on the binding of warfarin to humanserum albumin. The dependence of the binding of war-farin to human serum albumin on the hydrogen, cal-cium, and chloride ion concentrations ... on the binding of warfarin to human serum albumin:stopped-ﬂow studies. J Clin Chem Clin Biochem 23,719–723.39 Vorum H & Honore B (1996) In uence of fatty acidson the binding of warfarin and ... the protein in the N state, and becomes larger (about 40 Hz) in the presence of satur-ating concentration of myristate. On the other hand,this contribution is almost negligible for HSA in the...

Tài liệu Báo cáo khoa học: Electrostatic role of aromatic ring stacking in the pH-sensitive modulation of a chymotrypsin-type serine protease, Achromobacter protease I pdf

... deviates from the original position. In the struc-tural deviation, the solvent ASA of the side-chain of His210increased with the decrease in size of the side-chain atresidue 169 (Table 1 and Fig. ... effect of the size of the residue at position 169 may berelated to the solvent accessibility of the side-chain of His210 (Fig. 3C). When the accessibility of the side-chain of His210 increased, the ... accessibility of His210. The size of the side-chain at residue 169 and the pK2showed a clear linear relationship (Fig. 3B). The pK2increased as the size of the residue at position 169 increased.The...

Báo cáo khoa học: Dual modulation of prothrombin activation by the cyclopentapeptide plactin pptx

... identiﬁedprothrombin as one of the plasma cofactors. In incubations of U937 cellswith prothrombin and Xa, plactin increased the formation of thrombin,which cleaved single-chain u-PA to afford the inactive ... 4). These properties of the plactin–prothrombin interaction suggested a change in the conformation of prothrombin after plactin bind-ing. We measured the intrinsic ﬂuorescence of prothrombin ... activateprothrombin, plactin D increased the level of a-throm-bin (Fig. 5B). Thus, the plactin D effects were increas-ing or decreasing the formation of a-thrombin without the accompanying conversion of...

Tài liệu Báo cáo khoa học: Molecular defect of isovaleryl-CoA dehydrogenase in the skunk mutant of silkworm, Bombyx mori ppt

... strainsrevealed the presence of a single point mutation in 1337 nucleotides of BmIVD. In the sku mutant, the 1127th guanine from the start codon was substitutedby thymine and none of the other sites ... acts in the third step of leucine degradation and the sku mutant accumulates branched-chain amino acids in haemolymph, thismutant may be useful in the investigation of unique branched-chain aminoacid ... wild-typeBmIVD indicated that all the side chains in the loopconnecting helices I and J are exposed on the surface of the monomer, pointing toward FAD or its neigh-bouring monomer in the tetramer....

Tài liệu Báo cáo khoa học: Solution structure of hirsutellin A – new insights into the active site and interacting interfaces of ribotoxins docx

... ribosomesproducing the a fragment [1,28]. Recently, the impor-tance of the N-terminal hairpin and loop 2 of ribotox-ins in protein functionality and protein–protein and protein–lipid interactions ... involved in membrane inter-action. The length of the N-terminal hairpin in HtA isintermediate between those in RNse T1 and a-sarcin,having 20 amino acids in HtA, 26 in a-sarcin and 12 in RNase ... structure of the remain-ing part is the same in both proteins, including a shortsegment (N56, C57 and D58) forming a turn of 310helix (D75, C76 and D77 in a-sarcin). The active site The active...

Tài liệu Báo cáo khoa học: Molecular aspects of rheumatoid arthritis: chemokines in the joints of patients pdf

... cytokines, including IL-1b, TNF-a and IFN-c. (B) Chemokines expressed in the joint recruit leukocytes into the joints. In addition to functioning in cell trafﬁcking, severalchemokines have other ... affects the small joints of the hands and feet. The in ammatory process is characterized by in ltration of in ammatory cellsinto the joints, leading to proliferation of synoviocytes and destruction ... leukocytes and chemokines and chemokinereceptors [2]. Chemokines are small, chemoattractantcytokines that play key roles in the accumulation of in ammatory cells at the site of in ammation. There-fore,...

Báo cáo khoa học: Functional analysis of a murine monoclonal antibody against the repetitive region of the ﬁbronectin-binding adhesins ﬁbronectin-binding protein A and ﬁbronectin-binding protein B from Staphylococcus aureus pot

... the effect of the proximities of the antibody-binding and Fn-binding sites, the interaction of the repeat with Fnmay be sterically hindered in the presence of the anti-body. The results of this ... staphy-lococcal adhesins, comprising an N-terminal region that binds ﬁbrinogen and elastin, and a C-terminal domain that interacts with ﬁbronectin. The C-terminal domain of ﬁbronectin-binding protein A is ... 9 and 10 from both adhesins. With the use of truncatedfragments of repeat 9 of ﬁbronectin-binding protein A, we mapped the antibody epitope to the N-terminal segment and the ﬁbronectin-binding...

Báo cáo khoa học: Identiﬁcation of tyrosine-phosphorylation sites in the nuclear membrane protein emerin pot

... membrane (INM). The ONM is part of the rough endoplasmic reticulum and folds at the nuclear pores into the INM, which is ﬁrmly attachedto the lamina by integral membrane proteins of the INM. The INM ... important in the context of a muscledystrophy is a muscle-speciﬁc interaction with the actin-binding spectrin-repeat proteins nesprin 1a and nesprin 2 [28,29].Since the different binding regions ... between the DNA ⁄ protein com-plexes of the heterochromatin protein BAF and emer- in s amino-terminal LEM domain (aa residues 2–44)[38], which similarly exists in the INM proteins MAN1 and LAP2...

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