Báo cáo khoa học: "Mapping between Compositional Semantic Representations and Lexical Semantic Resources: Towards Accurate Deep Semantic Parsing" docx
... Computational Linguistics Mapping between Compositional Semantic Representations and Lexical Semantic Resources: Towards Accurate Deep Semantic Parsing Sergio Roa†‡, Valia Kordoni† and Yi Zhang† Dept. of ... mapping between deep se- mantic representations and lexical semantic resources. A probabilistic model comprising Minimal Recursion Semantics (MRS) st...
Ngày tải lên: 08/03/2014, 01:20
... Tullio, Enrico Defranchi, Franca Salamino, Edon Melloni and Sandro Pontremoli Department of Experimental Medicine (DIMES), Section of Biochemistry and Centre of Excellence for Biomedical Research (CEBR), University ... calpain ligands and may accordingly induce changes in the conformation of the protease detectable by the mAb binding. To investigate this, we exposed immobilized calpain...
Ngày tải lên: 07/03/2014, 12:20
... xenotoxins. At the blood–brain barrier, and in placental trophoblasts, testis and bone marrow, it provides protection of vital body parts and, in the gut, liver and kidney, Pgp helps to eliminate ... [15–18]. On the other hand, MRP1 is present in virtually all human tissues and in most human tumor cell lines and tumor samples [4]. Using mice genetically deficient in both the mdr1a...
Ngày tải lên: 18/02/2014, 13:20
Báo cáo khoa học: Interactions between coenzyme B12 analogs and adenosylcobalamin-dependent glutamate mutase from Clostridium tetanomorphum pot
... coenzyme- binding and kinetic studies of AdoCbl analogs with glutamate mutase. Results Synthesis of MeCbi, AdoCbi and AdoCbi-GDP MeCbi and AdoCbi were successfully separated from unreacted MeCbl and AdoCbl and ... 50, 75 and 120 lm cofactor, and the K m and k cat for AdoCbi-GDP were determined in the presence of 20, 70, 100, 150 and 200 lm cofactor. The reaction was initiate...
Ngày tải lên: 07/03/2014, 04:20
Tài liệu Báo cáo khoa học: Thermal unfolding of smooth muscle and nonmuscle tropomyosin a-homodimers with alternatively spliced exons docx
... differ at exon 9 (and at the N-terminal exons 1 and 2). Thus comparison between skeletal and smTm isoforms does not allow the assignment of the transitions of smTm. Comparison between the three ... significantly increases the thermal stability and unfolding enthalpy of Tm, and reduces the difference in total enthalpy seen between smTm and nonmuscle Tm isoforms 5a and 5b (Fig...
Ngày tải lên: 19/02/2014, 07:20
Tài liệu Báo cáo khoa học: Interaction between very-KIND Ras guanine exchange factor and microtubule-associated protein 2, and its role in dendrite growth – structure and function of the second kinase noncatalytic C-lobe domain docx
... compilation ª 2011 FEBS 1661 Interaction between very-KIND Ras guanine exchange factor and microtubule-associated protein 2, and its role in dendrite growth – structure and function of the second kinase ... dendrites and soma, although not to axons. The expression of three other KIND2-containing constructs (DKIND1, DRasN and DGEF) was restricted to dendrites and soma (Fig. 1B)....
Ngày tải lên: 14/02/2014, 19:20
Tài liệu Báo cáo khoa học: Relationships between structure, function and stability for pyridoxal 5¢-phosphate-dependent starch phosphorylase from Corynebacterium callunaeas revealed by reversible cofactor dissociation studies doc
... citrate and 0.1 M cysteine hydrochloride, in short, the resolution buffer. Various pH values between 5.0 and 8.0 were tested, and a pH of 7.0 was chosen (see below). Prior to the resolution, CcStP and ... potassium phosphate between < 0.05 and 80 m M . PLP at a concentration of between 0.0 and 100 l M was added to reconstitute the holo-enzyme. The reaction was carried out...
Ngày tải lên: 19/02/2014, 16:20
Tài liệu Báo cáo khoa học: Mapping the functional domains of human transcobalamin using monoclonal antibodies pptx
... Assembly of two domains achieved the composite structure of the ligand-binding site and built the compatible interface between IF and its receptor [14]. The domain organization of TC remains unknown ... peptides TC y46 ,TC y37 and TC y31 . How- ever, among the group 1 mAbs, only 3C12 and TC2 bound to all the fragments, whereas 2-2 and 4-7 did not recognize TC y31 (Fig. 4A, lanes 2...
Ngày tải lên: 20/02/2014, 01:20
Tài liệu Báo cáo khoa học: Mapping of the epitope of a monoclonal antibody protecting plasminogen activator inhibitor-1 against inactivating agents pptx
... on b-sheet A and the flexible joint region. Curiously, the epitope is localized in a-helix C and the loop connecting a-helix I and b-strand 5A, on the side of PAI-1 opposite to b-sheet A and distantly ... ± 0.5 E55/71A-Q58/74A hC K and R >20 000 a 1.6 ± 0.3 E55/71A-D307/318A hC and hI/s5A loop K and D >20 000 a 3.6 ± 1.1 Q58/74A-D307/318A hC and hI/s5A loop R and D >...
Ngày tải lên: 20/02/2014, 11:20
Tài liệu Báo cáo khoa học: Interactions between M proteins of Streptococcus pyogenes and glycosaminoglycans promote bacterial adhesion to host cells pdf
... cells and fibroblasts were labelled with [ 35 S]sulfate, washed and incubated with chondroitinase ABC and HS lyase. Triton extracts of untreated and enzymatic treated cells were prepared and analysed by ... 0.01 M N-ethylmaleimide, 1% Triton X-100 and 5 lgÆmL )1 ovalbumin. Extracts were precipitated with three volumes of 95% ethanol and 0.4% sodium acetate and were then dissolv...
Ngày tải lên: 20/02/2014, 11:20