Báo cáo khoa học: "Contradictions and Justiﬁcations: Extensions to the Textual Entailment Task" ppt

Tài liệu Báo cáo khoa học: "A Logic-based Semantic Approach to Recognizing Textual Entailment" ppt

... between the text and the hypothesis. The cost of deleting aword from is equal to 0, the costof replacing a word from with another from, where and and arenot synonyms in WordNet equal to (we ... combined: and have to be compatiblewith respect to the part-of-speech of the commonargument. Depending on their properties, thereare up to 8 combinations between any two se-mantic relations and their ... conjunctions into their constituentsso that other axioms can be applied, individually, to the components. These axioms are made avail-able only to the pair that generated them.For example, the axiom...

Tài liệu Báo cáo khoa học: Structural and mechanistic aspects of ﬂavoproteins: probes of hydrogen tunnelling pptx

... (related to the de Broglie wavelength of the H or D) and DGàis the Marcus activation energy. The activation energy isdescribed by the driving force, DG0, and reorganizationenergy in the standard ... reac-tion. Stopped-ﬂow traces of the observed FMN reduction during the reaction of the wild-type (wt) and N189A mutant of MR withNADH. The wt trace is ﬁt to a single exponential and the N189Atrace to ... viscosity, is the contribution of the protein friction to the total friction of the system. The activation entropy and enthalpy can be deter-mined independently from the temperature dependenceof the...

Tài liệu Báo cáo khoa học: Characterization of ICAM-4 binding to the I domains of the CD11a/CD18 and CD11b/CD18 leukocyte integrins pptx

... investigated the effect of divalent cations on the binding of ICAM-4transfectants to the I domains of CD11a and CD11b and compared the results to the divalent cation requirementsof ICAM-1 and ICAM-2 ... binding to the captured ICAM-4Fc strengthens the earlier results that the binding sites for the CD11a and CD11b I domains in ICAM-4 are different although theycould be partially overlapping [14]. The ... Factor Xa(Boehringer Mannheim). The biotin-labeled Factor Xa wasremoved using a streptavidin gel and the free GST using the glutathione resin. To release the recombinant CD11bI domain the...

Tài liệu Báo cáo khoa học: Kinetics and thermodynamics of nick sealing by T4 DNA ligase pptx

... phase of the joining of the mismatching oligonucleotide M5C19 corresponds to the maximal concentration of ATPÁMg. On the otherhand, the rate of the burst phase of joining of M5C19, and the joining ... pre-equilibrated to ambient temperature in the drive syringes and rapidly mixed in the stopped ﬂowinstrument, triggering the reaction.Results and discussionTime course of the joining reaction To study the ... decrease in the end-joining rateat low [ATP]: either the binding of the nucleotide to the ligase becomes rate limiting, or the equilibrium shiftstowards the nonadenylated enzyme. From the pre-steady-state...

Tài liệu Báo cáo khoa học: A role of miR-27 in the regulation of adipogenesis ppt

... Schemes 3 and 4).These results suggest that miR-27 exerts its inhibitoryeffects at or before the adipogenic commitment stage and that the IDM-induced genes appear to overcome the inhibitory effects ... Taken together, these results illustratea critical and speciﬁc role of miR-27 in the regulationof adipogenic differentiation.miR-27 prevents the induction of PPARc and C⁄EBPaIn order to delineate ... characterized by the transcriptionalinduction of: (a) the early genes C ⁄ EBPb and C ⁄ EBPd; (b) the determination genes PPARc and C ⁄ EBPa, also regarded as master regulators of adipo-genesis; and (c)...

Tài liệu Báo cáo khoa học: Reversible tetramerization of human TK1 to the high catalytic efﬁcient form is induced by pyrophosphate, in addition to tripolyphosphates, or high enzyme concentration ppt

... high Km and the tetramer has low Km, and the ratio between the two forms depends on the dThdconcentration [24]. According to this model, the simul-taneous presence in the assay of the two ... (see Table 1). Therefore, it can be concludedthat the nature of the base is insigniﬁcant for the tetra-merization effect. The next goal was to determine the role played by the sugar and phosphate ... than the other dNTP pools [4].In most cells and organisms except for a few para-sites, the dNTPs are provided by two main routes, the de novo and the salvage pathways. The central enzymein the...

Tài liệu Báo cáo khoa học: Evidence for noncooperative metal binding to the a domain of human metallothionein ppt

... respect to the lability of the zinc ions and that, despite the increased thermodynamic stability of the a domain with Zn2+over the b domain, the Zn2+sites in the a domain were shown to be more ... of the a domain ofrhMT-1a, showing the connectivities of the four divalent metal cations to the 11 cystei-nyl sulfurs. The numbering of the cysteines(1–11 starting from the N-terminus) and the four ... initially to the a domain, thereby lead-ing to formation of the M4a cluster prior to formationof the M3b cluster, demonstrating that the individualbinding constants of divalent metal ions for the a...

Tài liệu Báo cáo khoa học: Fermentative lifestyle in yeasts belonging to the Saccharomyces complex ppt

... biosynthesis of sterols and fatty acids,heme ⁄ hemoproteins, NAD, and uracil [7,8]. The abil-ity to translocate ATP produced in the cytoplasm intomitochondria, and the ability to adjust the ... for their ability to ferment, grow in the absence of oxygen, and gener-ate stable petites, and we attempted to determinewhether these traits were expressed in the progenitoryeasts, and whether ... NADHgeneration, due to amino acid biosynthesis. Much of the generation of NADH during amino acid biosyn-thesis takes place in the mitochondria. Because of the block in the respiratory chain caused by the additionof...

Tài liệu Báo cáo khoa học: "A Novel Feature-based Approach to Chinese Entity Relation Extraction" ppt

... strictly bottom-up (i.e. use the identified subtype to choose the type it belongs to) , guiding top-down (i.e. to classify types first and then subtypes under a certain type). However, these two ... said to be co-referenced to one entity if they refers to the same entity in the world though they may have different surface expressions. For example, both “he” and “Gates” may refer to “Bill ... types and 18 subtypes of relations are annotated. We use 75% of it to train SVM classifiers and the remaining to evaluate results. The aim of the first set of experiments is to examine the...

Báo cáo khoa học: A novel 2D-based approach to the discovery of candidate substrates for the metalloendopeptidase meprin pot

... interesting candidate spots to wrong spots in the reference gel leads to misinterpretation of the data set and protein spots unique to only one speciﬁc conditionare then not properly displayed in the ... Corporation) and then diluted with buf-fer to a ﬁnal volume of 450 lL. The total volthour productwas increased to approximately 80 kVh. The cathodic paperwick was immersed in 1% (w ⁄ v) dithioerythritol ... ofasparagine and glutamine. Parent and fragment mass toler-ances were set to 1 Da. Up to two missed cleavages and half tryptic peptides were allowed. The taxonomic searchspace was restricted to Mammalia...

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