Báo cáo khoa học: "That’s What She Said: Double Entendre Identification" doc

... what she said”, completing the joke. While somewhat ju- venile, this joke presents an interesting natural lan- guage understanding problem. A “that’s what she said” (TWSS) joke is a type of double ... 89–94, Portland, Oregon, June 19-24, 2011. c 2011 Association for Computational Linguistics That’s What She Said: Double Entendre Identification Chlo ´ e Kiddon and Yuriy Bru...

Ngày tải lên: 07/03/2014, 22:20

... [c 32 P]ATP using T4 polynucleo- tide kinase (Scientific Industrial Corp. SibEnzyme) and annealed to form double stranded probes. EMSA was performed as described previously [34]. Reaction mixtures contained ... probe (10 5 cpmÆmL )1 ) was added and incubated for 1 h at room temperature. The membrane was washed to remove nonspe- cifically bound DNA and subjected to autoradiography. The relativ...

Ngày tải lên: 07/03/2014, 05:20

... kinase –C129 Glucokinase (a-helix); C131 GlcNAc kinase – C233 Glucokinase (b-sheet); C143 GlcNAc kinase – C252 Glucokinase (b-sheet); C211 GlcNAc kinase –C371 Glucokinase (a-helix); C217 GlcNAc kinase – ... different algorithms were used to find the lowest common denominator with regard to a-helices and the b-sheets. Three-dimensional modelling was performed using the RASMOL software. RESULTS...

Ngày tải lên: 08/03/2014, 10:20

... drug addicts developed irre- versible and severe PD symptoms following self-admin- istration of what they hoped to be synthetic heroin [7]. The highly lipophilic substance that they had synthe- sized, ... mouse models with mutant or wild-type LRRK2 overexpression or null mutation have not yet been published. None of the genetic models based on PD-linked genes recapitulate the key symptoms o...

Ngày tải lên: 07/03/2014, 05:20

... an oligopeptide from a b-sheet to an a-helix: a model for amyloid formation. Proc Natl Acad Sci USA 94, 23–28. 58 Ferna ´ ndez A (2005) What factor drives the fibrillogenic association of b-sheets? FEBS Lett ... [28] proposed that two kinds of b-structure are possible: the b-sheet that is observed in the mature fibrils and the a-pleated sheet [29], which could be the structure in the prefibril...

Ngày tải lên: 14/02/2014, 18:20

... neuronal growth-inhibitory activity of GIF [6,17]. The bioactivity of GIF is com- pletely abolished by a double mutation from Cys6- Pro7-Cys8-Pro9 to either Cys6-Ser7-Cys8-Ala9 (the P7S ⁄ P9A mutant) ... factor; MT, metallothionein; NO, nitric oxide; pDB, protein data bank; rlMT2, rat liver MT2; sGIF, sheep neuronal growth-inhibitory factor; SNOC, S-nitrosocysteine. 2912 FEBS Journal 277 (2...

Ngày tải lên: 16/02/2014, 15:20

Ngày tải lên: 17/02/2014, 05:20

... secreting active variants, three chimeric laccases (LAC131, LAC232 and LAC535), each resulting from double crossovers, were purified, and their apparent kinetic parameters were determined using 2,2¢-azino-bis(3-ethylbenzthiazoline-6-sulphonic ... technologi- cal and bioremediation processes, in addition to their use in organic synthesis, have been published [5]. For industrial use, the curre...

Ngày tải lên: 18/02/2014, 06:20

... intimately related to susceptibility to transmissible spongiform encephal- opathies, such as scrapie in sheep, bovine spongiform encephalopathy, chronic wasting disease in deer, and Creutzfeldt–Jakob ... Transmissible spongiform encephalopathies are related to the conver- sion of PrP C to a protease-resistant b-sheet-rich ‘scrapie form’ [2]. The gene encoding PrP has been sequenced [3,4], and...

Ngày tải lên: 18/02/2014, 08:20