Báo cáo khoa học: "Finding Deceptive Opinion Spam by Any Stretch of the Imagination" pptx
... insidi- ous type of opinion spam: DECEPTIVE OPINION SPAM fictitious opinions that have been deliber- ately written to sound authentic, in order to deceive the reader. For example, one of the following ... opinion spam detection. Furthermore, most previous work in the area has focused on the detection of DISRUPTIVE OPINION SPAM uncontroversial instances of spam...
Ngày tải lên: 07/03/2014, 22:20
... and in the range of the CV of the NADPH determination. Discussion Obvious tendencies found by characterization of the wild-type In the exponential phase of the ammonium cultures all of the PPP ... [26]. Overproduction of 6PGDH resulted in an increase of synthesis of pyr- idine nucleotide cofactors, as the total pool of these increased. Whether the synthes...
Ngày tải lên: 07/03/2014, 17:20
... mice [28]. The instability of DA at the neutral pH of the cytosol causes the forma- tion of toxic aminochromes, and these species are not formed when DA is protonated at the acidic pH of the storage ... counter. Values are the mean of six replicates. The specific uptake was determined by subtracting the uptake counts in the absence of inhibitor from the upta...
Ngày tải lên: 14/02/2014, 21:20
Tài liệu Báo cáo khoa học: Mixed lineage leukemia: a structure–function perspective of the MLL1 protein ppt
... coordinates two zinc ions using the two conserved CGXCXXC motifs (Fig. 2A). The zinc ions are required for the structural integrity of the protein, as mutation of any of the cysteine residues involved ... observation). In the ternary complex, the histone H3 peptide binds in a deep chan- nel that divides a pair of acidic lobes, one of which is composed of residues f...
Ngày tải lên: 16/02/2014, 14:20
Tài liệu Báo cáo khoa học: Neuronal growth-inhibitory factor (metallothionein-3): evaluation of the biological function of growth-inhibitory factor in the injured and neurodegenerative brain pdf
... in all of these conditions [22]. In the trau- matically injured brain, however, the synthesis of MT1 and MT2, as well as the synthesis of GIF, are up-regu- lated by reactive astrocytes in the vicinity ... fine processes of these cells. Astrocytic synthesis of GIF is mainly found in the cortex, brainstem and spinal cord [6]. Additionally however, there are also consistent...
Ngày tải lên: 16/02/2014, 15:20
Tài liệu Báo cáo khoa học: Compartmentalization and in vivo insulin-induced translocation of the insulin-signaling inhibitor Grb14 in rat liver pptx
... [6] and inhibits the tyrosine kinase activity of the IR [7]. On the basis of the crystal structure of the tyrosine kinase domain of the IR in complex with the PIR ⁄ BPS domain of Grb14, Depetris ... Although the interaction of Grb14 with the IR is probably the major determi- nant of the insulin-induced membrane translocation of Grb14, several lines of e...
Ngày tải lên: 18/02/2014, 18:20
Tài liệu Báo cáo khóa học: Quantitative analysis, using MALDI-TOF mass spectrometry, of the N-terminal hydrolysis and cyclization reactions of the activation 2 process of onconase pdf
... (Met1)-ONC (M23L) by the addition of AAP, as described in the Materials and methods. Completion of the hydrolysis was confirmed by the disappearance of the (Met1)-ONC (M23L) signal in the MALDI-TOF mass ... analyzed by MALDI-TOF MS. The addition of the protease is considered the zero time point. The relative intensities of the peaks from the mass spectra...
Ngày tải lên: 19/02/2014, 12:20
Báo cáo khoa học: Physicochemical properties and distinct DNA binding capacity of the repressor of temperate Staphylococcus aureus phage /11 doc
... homol- ogy over the entire length of the k repressor. Interest- ingly, although the sequences of the C-terminal ends of the above S. aureus phage repressors are identical, the sequences of their N-terminal ... major groove of the DNA helix [1]. Therefore, the data also suggest that the interaction between CI and the opera- tor DNA may occur through the major gr...
Ngày tải lên: 07/03/2014, 00:20
Báo cáo khoa học: A mouse model for in vivo tracking of the major dust mite allergen Der p 2 after inhalation docx
... that the clearance and further metabo- lism of the allergen was altered as a result of the inflammation in the lungs of sensitized animals. Up to now there are few data available on the fate of ... confluent monolayers of epithelial cells [15]. All these activities may contribute to the allerge- nicity of HDM by favouring a pro-inflammatory envi- ronment in the airway...
Ngày tải lên: 07/03/2014, 21:20
Báo cáo khoa học: Two separate regions essential for nuclear import of the hnRNP D nucleocytoplasmic shuttling sequence ppt
... mediated by Trn-1. Results Determination of hnRNP D NLS The exon 8 of hnRNP D encodes the 21 amino acids sequence common to all the isoforms D01, D02, D1, and D2 (Fig. 1A) [23]. To examine whether the ... for the nuclear import. Results on mt9 suggested that phosphorylation of the tyrosine residue is not related to the nuclear import. Then, the role of these two resi...
Ngày tải lên: 07/03/2014, 21:20