Báo cáo khoa học: The cytochrome P450scc system opens an alternate pathway of vitamin D3 metabolism docx

... 2005 FEBS The cytochrome P450scc system opens an alternate pathway of vitamin D3 metabolism Andrzej Slominski 1 , Igor Semak 2 , Jordan Zjawiony 3 , Jacobo Wortsman 4 , Wei Li 5 , Andre Szczesniewski 6 and ... NMR analysis of P1 and P3. NMR analysis of compound P1 showed that it represents 20-hydroxyvitamin D3 (Fig. 2, Fig. S1). Compared with vitamin D3 and a...

Ngày tải lên: 07/03/2014, 21:20

... available: • The URL of the relevant newspaper article. • The date and time of the comment. • The author ID associated with the comment. 5 • The subtitle header. 5 • The author’s e-mail address. 5 • The ... rare languages. In the same vein, Zaidan and Callison-Burch (2011) solicit English translations of Urdu sentences from non-professional translators, and show that...

Ngày tải lên: 20/02/2014, 04:20

... descriptive analysis of the grapheme-phoneme mapping system of the French orthography, and we further explore the sensitivity of adult human readers to some characteristics of this mapping. The results ... implementations of the dual-route theory (Coltheart et aL, 1993). The "central dogma" of this theory is that the performance of human subjec...

Ngày tải lên: 20/02/2014, 19:20

... linguists and internet users as they search for relevant material, and then clas- sify and annotate this material. 1 Introduction There's a wide class of documental management solutions and products ... daily work. The system offers facilities to assist linguists and inter- net users as they search for relevant material, and then classify and annotate this material in a reposi- tor...

Ngày tải lên: 31/03/2014, 20:20

... transcription factors as the mutation of the CRE site within the COX-2 promoter or the expression of a dominant negative mutant of CREB reduces inducibility of the COX-2 promoter [9,12–14]. The ... assessing the effects of the dominant negative ESE-1 on endogenous COX-2 mRNA levels. Therefore, we evaluated the effects of the dominant-negative ESE-1 mutants in R...

Ngày tải lên: 19/02/2014, 17:20

... sentences, their annotations, and the Web page where the example occurred. 2.2 Built-In and Custom Collections Linguistically annotating and indexing the entire Web is beyond impractical, and therefore ... examples of this construction, such as The higher the rating, the lower the interest rate that must be paid to investors; The more you bingo, the more chances y...

Ngày tải lên: 20/02/2014, 15:20

... and PM (6.28 · 10 3 mol )1 Æs )1 ) by PKH. This reflects the antivitamin character of both compounds and explains a depletion of cofactor formation in the organism in the presence of the antivitamins. The ... plays an important role in deter- mining the kinetic features of PKH. However, the data for the catalytic efficiency of ginkgotoxin and DPN are of the same...

Ngày tải lên: 07/03/2014, 10:20

... these lesions and the abundant undamaged DNA present in the genome (including the intact DNA strand opposite the lesion). Depending on the precise location of the damaged DNA, the NER pro- cess ... between the NER system and other cellular pathways is also achieved by selected binding of the various structural domains. Here, we summarize recent studies on the domain...

Ngày tải lên: 07/03/2014, 12:20

... order to further examine the hypothesis that the target of J-ACTX- Hv1c is an insect K Ca channel, we investigated whether the toxin could produce an additional block in the presence of maximal ... further probe the functional relevance of these residues and to investigate the role of individual chemical moieties in the toxin’s interaction with insect BK Ca channels,...

Ngày tải lên: 16/03/2014, 06:20

... . they can approach questions systematically and on a grand scale. They can study . . . how tens of thousands of genes and pro- teins work together in interconnected networks to orchestrate the ... Broman Olsen, and Mona Diab. 1999. The Bible as a parallel corpus: Annotating the ‘book of 2000 tongues’. Computers and the Hu- manities, 33:129–153. Kevin Scannell. 2008. The Cr ´...

Ngày tải lên: 16/03/2014, 23:20