Báo cáo khoa học: BCR kinase phosphorylates 14-3-3 Tau on residue 233 pdf

... 2259–2265. BCR kinase phosphorylates 14-3-3s on residue 233 S. J. Clokie et al. 3776 FEBS Journal 272 (2005) 3767–3776 ª 2005 FEBS BCR kinase phosphorylates 14-3-3 Tau on residue 233 Samuel J. ... C-terminal region has recently been proposed as a general inhib- itor of 14-3-3 ligand interactions [36]. The observation here that BCR phosphorylates 14-3-3 on...

Ngày tải lên: 07/03/2014, 21:20

... ubiquitination, internalization and degradation [9,10]. Recently it was demonstrated that the aldosterone-induced kinase sgk (serum and glucocorti- coid dependent kinase) phosphorylates Nedd4-2 on two serines ... Partial inhibition of b Fig. 1. Phosphorylation of different fusion proteins by kinase enriched fractions. (A) Matched comparison of the phosphorylation of GST-b and GST-c by...

Ngày tải lên: 21/02/2014, 03:20

... protein kinase susceptible to proteolytic degradation at the G 1 ⁄ S transition in the cell-division cycle, whereas the non-phosphorylated version is resistant. Abbreviations Aky2p, adenylate kinase ... mutation is constituted by Cdc37p, a kinase- associated molecular chaperone required in concert with Hsp90p in the regulation of the activity of several signalling protein kinases. Mutat...

Ngày tải lên: 18/02/2014, 16:20

... nhau trong tit ci cic phong cich cbiic nang kbic nhau, song dae biet li ddi vdi phong cich hinh chfnh cdng vu. De xay dung hinh inh ehinh quyen, gay dupc thien cim vdi ngudi dan, trong giao ... ttr. Trong dd, am gipng la phuong tien truyen tii, ngdn ttr bieu dat dd'i tupng ciia sir truyen tii. Ngdn ngir giao tiep ciia con ngudi tdn tai dudi hai dang co bin la ndi (phong cich .....

Ngày tải lên: 18/02/2014, 03:20

... mRNA or a non-targeting (NT) siRNA at a final concentration of 10 n M. Fluorescence was measured 24 h after transfection. The mean and standard deviation are shown for each condition. Asterisks ... silencing showed a concomitant reduction in binding at the expected location (Fig. S3). Based on molecular weight, both the Dicer and TRBP complexes are assumed to contain only one molecule each ....

Ngày tải lên: 18/02/2014, 06:20

... then transfer the second electron to FAD yielding O-pro- tonated acetyl phosphate and two-electron reduced FAD. The reaction is then completed by deprotona- tion of acetyl phosphate. Reaction mechanism ... Biophys Acta 25, 650–651. 32 Hoffman MZ & Hayon E (1972) One-electron reduction of disulfide linkage in aqueous-solution – formation, protonation, and decay kinetics of RSSR-radical. JAm...

Ngày tải lên: 18/02/2014, 08:20

... in two distinct conformations in E53QbsSHMT-Gly. In one conformation, the carbox- ylate group forms hydrogen bonds with R357, as in bsSHMT-Gly [12]. In the second conformation, the carboxylate ... present close to the position corresponding to the second conformation of the carboxylate group (Fig. 2A,B). The hydrogen bonding between Q53 and the second conformation of carbo- xylate of Gly ......

Ngày tải lên: 18/02/2014, 16:20

... mixtures on a chromatographic timescale (500 ms ⁄ protein). Abbreviations CAD, collision-activated dissociation; ECD, electron-capture dissociation; ESI, electrospray ionization; ETD, electron-transfer ... Journal compilation ª 2007 FEBS 6271 dimethylation of Arg, monomethylation, dimethylation and trimethylation of Lys, acetylation and ubiquitina- tion of Lys, and phosphorylation of Ser an...

Ngày tải lên: 18/02/2014, 16:20

... serine ⁄ threon- ine kinase belonging to the family of AGC kinases, which includes protein kinase A (PKA), protein kinase B (PKB ⁄ Akt), protein kinase C (PKCs), p90 ribosomal S6 kinase and 3-phosphoinositide-dependent ... interaction is exerted via the S6K kinase and ⁄ or the kinase extension domain. The positions of the trun- cated S6Ks are indicated with arrows. Similarly, wh...

Ngày tải lên: 19/02/2014, 07:20

... Russian-English Dictionary", Machine Translation of Languages, John Wiley and Sons, New York (1955), pp. 47-65. last approach has been considered in a recent paper on mechanical translation 3 where ... stage a simplification may be effected if the computer dictionary is concerned only with a certain field (e.g., nu- clear physics), in which case only those terms which may reas...

Ngày tải lên: 19/02/2014, 19:20