Báo cáo khoa học: 7-Ketocholesterol-induced apoptosis Involvement of several pro-apoptotic but also anti-apoptotic calcium-dependent transduction pathways ppt
Báo cáo khoa học: Context-dependent effects of proline residues on the stability and folding pathway of ubiquitin docx
... kinetic elucidation of folding pathways and t he ability to ide ntify partially folded intermediate states or parallel folding pathways [13–21]. However, the observation of a wide variation in the amplitude of ... terms of entropic effects on the flexibility of the polypeptide back- bone si nce i n one case removal of proline leads to an enhancement of stability. The side cha...
Ngày tải lên: 07/03/2014, 16:20
Báo cáo khoa học: A biophysical view of the interplay between mechanical forces and signaling pathways during transendothelial cell migration doc
... influence of these mechanical forces, not only as possible sources of outside-in signaling, but also as a form of feedback for the reorganization of the endo- thelium. Mechanical properties of the ... cellular behavior. These effects are discussed later for the case of ECs. Another study also shows involvement of small GTPases of the Rho family in the EC response to she...
Ngày tải lên: 22/03/2014, 21:20
Tài liệu Báo cáo khoa học: Minor capsid proteins of mouse polyomavirus are inducers of apoptosis when produced individually but are only moderate contributors to cell death during the late phase of viral infection ppt
... inducers of apoptosis We further examined the character of cell death induced by VP2 or VP3 proteins. To assess the con- tribution of apoptosis to toxicity, we evaluated the cleavage of both effector ... levels of apoptotic markers during the late stages of MPyV infection. However, comparison of the levels of apoptotic markers and cytotoxicity during the replication of w...
Ngày tải lên: 16/02/2014, 09:20
Báo cáo khoa học: Comprehensive sequence analysis of horseshoe crab cuticular proteins and their involvement in transglutaminase-dependent cross-linking potx
... acid composition of the various types of cuticle of Limulus polyphemus. J Insect Physiol 15, 495–507. 24 Larsen NJ (1975) Isolation and characterization of proteins from the cuticle of Limulus polyphemus. ... abundance of Ser (9– 12%). The members of acidic DE group had a high content of Asp (14%) and Glu (10–14%). N-Terminal amino acid sequence analysis of HMM chitin-bindin...
Ngày tải lên: 07/03/2014, 21:20
Báo cáo khoa học: ATP-binding domain of heat shock protein 70 is essential for its effects on the inhibition of the release of the second mitochondria-derived activator of caspase and apoptosis in C2C12 cells potx
... respect to the role of HSP70 in the inhi- bition of the release of Smac and apoptosis. The role of the ATP-binding domain of HSP70 in the prevention of the release of Smac and apoptosis after exposure ... inhibition of caspases by inhibitor of apoptosis protein (IAP) and is known to be a new and important regulator of apoptosis in a variety of cancer cells. The e...
Ngày tải lên: 16/03/2014, 01:20
Báo cáo khoa học: Enhanced apoptosis through farnesol inhibition of phospholipase D signal transduction pdf
... DAG (downstream of the alcohol block of PLD) to rescue cells from the augmentation of farnesol-induced apoptosis by primary alcohols. In the presence of primary alcohols DAG, but not PC, rescued ... over-expression of PKCa prevents or attenuates apoptosis in many cell types, whereas down- regulation of PKCa potentiates apoptosis [40–42]. Although the precise role of PKCa...
Ngày tải lên: 23/03/2014, 15:21
Báo cáo khoa học: p53-induced inhibition of protein synthesis is independent of apoptosis pdf
... some of these issues. Careful comparisons of the kinetics of translational down-regula- tion vs. the inhibition of cell cycle progression and induction of apoptosis show that the effect of p53 activation ... regulation of protein synthesis is simply a consequence of either the impairment of cell cycle progression or the induction of apoptosis, both of which are associ...
Ngày tải lên: 23/03/2014, 18:20
Báo cáo khoa học: "The clinical value of daily routine chest radiographs in a mixed medical–surgical intensive care unit is low"
... performance of a bronchoalveolar lavage for culture, or start of or a change in antimicrobial therapy in case of unex- pected infiltrates on the CXR; repositioning of tubes in case of malposition of orotracheal ... ultrasound of the thorax in case of pleural effusion on the CXR, start or change in medication (diuretics); insertion of a pleural drain; and repositioning of d...
Ngày tải lên: 25/10/2012, 10:39
Tài liệu Báo cáo khoa học: Multi-targeted activity of maslinic acid as an antimalarial natural compound pdf
... the processing of apicoplast protein leader sequence. Inhibition of any of these activities could contribute to MA interference in the maturation of the parasite. Polypharmacology of MA The observed ... activities required for the maturation of the trophozoite. MA might also specifically inhibit metalloproteases of the thermolysin class M16. Several candidates of this famil...
Ngày tải lên: 14/02/2014, 14:20
Tài liệu Báo cáo khoa học: C-Terminal extension of a plant cysteine protease modulates proteolytic activity through a partial inhibitory mechanism doc
... Leu23 of the CT-extension of the rmErv-C +CT molecule with a minimum distance of 1.9 A ˚ between two atoms of the two leucines (Fig. 8A). Because the Leu23 residue of the CT-extension of the ... into the unprimed subsites of Erv-C with Leu23 in the S2 pocket, considering the specificity of Erv-C towards a Leu residue [17]. The mode of interactions of mini-chain of human l...
Ngày tải lên: 14/02/2014, 14:20