Báo cáo khoa học: "Exploring Deterministic Constraints: From a Constrained English POS Tagger to an Efﬁcient ILP Solution to Chinese Word Segmentation" ppt

... formulated as character tagging, analogousconstraints can be learned with the same templatesas English POS tagging. High-quality constraintscan be learned with respect to a special tagset, ... (CWS)3.1 Word segmentation as character taggingConsidering the ambiguity problem that a Chinese character may appear in any relative position in a word and the out-of-vocabulary (OOV) problem thatit ... (Zhangand Clark, 2007) and (Jiang et al., 200 8a) .We propose an Integer Linear Programming (ILP) formulation of word segmentation, which is nat-urally viewed as a word- based model for CWS.Character-based...

Báo cáo khoa học: "Learning Semantic Links from a Corpus of Parallel Temporal and Causal Relations" doc

... These works annotated temporal relationsbetween events and times, but low inter-annotatoragreement made many TimeBank and TempEvaltasks difﬁcult (Boguraev and Ando, 2005; Verha-gen et al., 2007). ... lemmas and part-of-speech tags,e.g. took, take, VBD and began, begin, VBD.• All words, lemmas and part-of-speech tags in theverb phrases of each event, e.g. took, take, VBDand began, to, trade, ... achieving an F-measure of 49.0 for temporals and 52.4for causals. Analysis of these models sug-gests that additional data will improve perfor-mance, and that temporal information is cru-cial to causal...

Tài liệu Báo cáo khoa học: Crystal structure of importin-a bound to a peptide bearing the nuclear localisation signal from chloride intracellular channel protein 4 ppt

... peptide atoms) and rjis the standard deviation of Bfactors. The normalized B factors have a zero mean and unitvariance. All atoms that satisfy Bz‡ 4 are treated as outliersand discarded. After ... removed, and atomic B factorsreset to an appropriate value as suggested from the Wilsonplot. An initial solvent model was built using arp ⁄ warp [39],which was then manually checked and validated ... importin -a nuclear import pathway, provided that CLIC4 can undergo a conforma-tional rearrangement that exposes the NLS in an extended conformation.DatabaseStructural data are available in...

Tài liệu Báo cáo khoa học: The multicopper oxidase from the archaeon Pyrobaculum aerophilum shows nitrous oxide reductase activity docx

... (N2O) to dinitrogen by Bacteriaand Archaea. Adv Microb Physiol 52, 107–227.24 Uthandi S, Saad B, Humbard MA & Maupin-FurlowJA (2010) LccA, an archaeal laccase secreted as a highly stable ... of plant ascorbate oxidase [33], human ceru-loplasmin [34], CotA laccase from B. subtilis [35], andMcoA from A. aeolicus [4], and they apparently cor-relate with a structural organization ... Pereira L, Coelho AV, Viegas CA, Ganachaud C,Iacazio G, Tron T, Robalo MP & Martins LO (2009)On the mechanism of biotransformation of theanthraquinonic dye blue 62 by laccases. Adv SynthCatal...

Tài liệu Báo cáo khoa học: Enzyme kinetics informatics: from instrument to browser pdf

... normalize it to agreed standards andﬁnally transfer these data to publicly available data-bases to make them accessible. To facilitate the dissemination of data, a number ofinitiatives have been ... steps automatically, ensuring thatboth experimental data and derived kinetic parametersare captured and stored immediately upon acquisitionand analysis.Data accessAccess to the submitted data ... providing a link from kinetic parameters to raw data and vice versa. An advantage of this approach is that it uncouplesthe storage of raw data from the storage of derivedkinetic parameters, such that...

Tài liệu Báo cáo khoa học: Multisite protein phosphorylation – from molecular mechanisms to kinetic models pdf

... Raghavan A, Tahiliani M, Zhang X, Qin J,Hogan PG, Rao A (2000) Concerted dephosphoryla-tion of the transcription factor NFAT1 induces a conformational switch that regulates transcriptionalactivity. ... effec-tive rate constants of phosphorylation and dephosphor-ylation, a ranand bran, deﬁned as follows: a ran¼ðN À n þ 1 a and bran¼ nb; ð6Þwhere a and b are as given in Eqn (5). Equation (6)expresses ... transcription fac-tor NFAT (nuclear factor of activated T cells) by calcineurin (CaN) atseveral Ser residues induces a conformational change that exposes a nuclear localization signal (NLS), leading to...

Tài liệu Báo cáo khoa học: Catalytic mechanism of SGAP, a double-zinc aminopeptidase from Streptomyces griseus pdf

... onbiochemical and structural data, a general catalyticmechanism was proposed for aminopeptidases thatinvolves an acidic residue acting as a general acid ⁄ gen-eral base and a di-nuclear metal center ... activates a zinc-bound water molecule and an addi-tional residue (Tyr246) polarizes the carbonylcarbon and stabilizes the transition state.Glu131 is thought to act as a general baseand to generate ... thanthat of SGAP. The activated state can be viewed as an unstable transient phase in which bonds and their orien-tations are disordered [60]. It is possible that, in SGAP,the transition state...

Tài liệu Báo cáo khoa học: Aldehydes release zinc from proteins. A pathway from oxidative stress⁄lipid peroxidation to cellular functions of zinc pptx

... Kitagawa K, Matsuno K, Matsumoto A, Yoshida A, Nakayama K, Nakayama K & Kawa-moto T (2002) Diminished alcohol preference in trans-genic mice lacking aldehyde dehydrogenase activity.Pharmacogenetics ... Roman J, Gimenez A, Lluis JM, Gasso M, Rubio M,Caballeria J, Pares A, Rodes J & Fernandez-Checa JC(2000) Enhanced DNA binding and activation of tran-scription factors NF-kappa B and AP-1 ... aldehyde group,whereas acrolein, an a, b-unsaturated aldehyde, forms a Michael adduct. The zinc-releasing activity of alde-hydes has implications for toxicologic and patho-biochemical mechanisms.AcroleinConcentrations...

Tài liệu Báo cáo khoa học: Production and characterization of a secreted, C-terminally processed tyrosinase from the ﬁlamentous fungus Trichoderma reesei ppt

... GAC ACA CAT CCC C; andreverse primer, GAT CGG TAC CTC ATT ACA GAGGAG GGA TAT GGG GAA C. The PCR reaction wasdone as described above. The ampliﬁed PCR product wasinserted into the EcoRI and ... lactose as a carbon source, 1% potassiumphthalate as a buffering agent (pH 5.5), 0.1 mm CuSO4and1% tyrosine as an indicator substrate was used. The trans-formants were streaked on the plates ... 919628.36 Yamada Y (1983) Production of heat-resistantpolyphenol oxidase, Japanese patent 61115488.37 Yamada Y, Tawara Y & Yoshika H (1983) Productionof heat-resistant polyphenol oxidase, Japanese...

Tài liệu Báo cáo khóa học: UDPgalactose 4-epimerase from Saccharomyces cerevisiae A bifunctional enzyme with aldose 1-epimerase activity docx

... Sequence analysis indicates thatthe yeast epimerase has an N-terminal domain (residues1–377) that shows signiﬁcant similarity with Escherichia coliand human UDPgalactose 4-epimerase, and a C-terminaldomain ... glycolysis, b-D-galactoseneeds to be transformed to a- D-galactose before beingphosphorylated by galactokinase. Mutarotase catalyzes theinterconversion of b-D-galactose to a- D-galactose, whichis ... UDPgalactose 4-epimerase from Saccharomyces cerevisiae A bifunctional enzyme with aldose 1-epimerase activitySiddhartha Majumdar1, Jhuma Ghatak2, Sucheta Mukherji2, Hiranmoy Bhattacharjee3and...

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