Báo cáo khoa học: Solution structure and backbone dynamics of the XPC-binding domain of the human DNA repair protein hHR23B docx
Tài liệu Báo cáo khoa học: Solution structure of hirsutellin A – new insights into the active site and interacting interfaces of ribotoxins docx
... Superposition of the active-site residues of the 20 conformers of the solu- tion structure of HtA. Catalytic groups E66 and H113 are shown in red, and side chains of other residues in their vicinity ... quality and precision of the 20 structures are summarized in Table 1, and a superposition and general view of the structures is shown in Fig. 2A,B. The me...
Ngày tải lên: 18/02/2014, 08:20
Tài liệu Báo cáo khoa học: Design, structure and biological activity of b-turn peptides of CD2 protein for inhibition of T-cell adhesion ppt
... at the N- and C-termini. A comparison of the b-turn structure of cER with the similar region in the crystal structure of rat and human CD2 was carried out. In the rat CD2 crystal structure, the ... structure in solution and clo- sely mimic the b-turn s tructure of the surface epitopes of the CD2 protein. Docking studies of CD2 peptides and CD5...
Ngày tải lên: 19/02/2014, 13:20
Tài liệu Báo cáo khoa học: Solution structure of crotamine, a Na+ channel affecting toxin from Crotalus durissus terrificus venom docx
... toxin structure and potential surface The characteristic NOE connectivities, reported in Fig. 3A, and the analysis of the / and w angle distribution allowed the identification of the type and boundaries ... [47] of the triple-stranded antiparallel b-sheet was Fig. 3. Summary of data used in the determination of the secondary structure of crotamine. (A) P...
Ngày tải lên: 20/02/2014, 11:20
Tài liệu Báo cáo khoa học: Solution structure of the matrix attachment region-binding domain of chicken MeCP2 ppt
... helix on the other face. It is thought that the two inner strands of the b-sheet lie within the major groove of the DNA and that a hydrophobic pocket formed by the side chains of Y123 and I125 ... [15]. The solution structure of the MBD of rat (r)MeCP2 has recently been determined [17]. The MBD adopts a wedge- shaped structure, composed of an antiparal...
Ngày tải lên: 21/02/2014, 00:20
Báo cáo khoa học: Solution structure of the catalytic domain of RICH protein from goldfish pot
... with the crystal structure of human CNPase cata- lytic domain (rmsd of 2.3 A ˚ over 205 residues). Sequence alignment of the catalytic domain of RICH and related proteins (Fig. 1B) identifies the ... close to its Fig. 2. Structure of goldfish RICH catalytic domain. (A) Stereo view of the backbone superposition of 10 lowest energy structures of the RICH c...
Ngày tải lên: 07/03/2014, 10:20
Tài liệu Báo cáo khoa học: Pronounced adipogenesis and increased insulin sensitivity caused by overproduction of prostaglandin D2 in vivo pptx
... obesity. Experimental procedures Generation of H-PGDS TG mice The coding region of human H-PGDS was cloned into the downstream sites of the chicken b-actin promoter and the CMV enhancer of the pCAGGS expression vector ... without fat, of WT and H-PGDS TG mice (n = 6). Continuous dissections of mouse fat and bone in the whole body were quantified by use of a mi...
Ngày tải lên: 16/02/2014, 09:20
Tài liệu Báo cáo khoa học: "NATURAL LANGUAGE AND COMPUTER INTEBFACE DESIGN MURRAY TUROFF DEPARTMENT OF COMPUTER AND IiVFORMATION SCIENCE IIEW JERSEY INSTITUTE OF TECHNOLOGY" ppt
... developing and evaluating the use of a computer as a direct aid to facilitating human communi- cation. The basic idea is to use the processing and logical capabilities of the computer to aid in the ... lines of text and the average comment or page is about 20 lines of text. EIES offers the user a complete set of differing inter- faces including menus, com...
Ngày tải lên: 21/02/2014, 20:20
Tài liệu Báo cáo khoa học: Crystal structure of the cambialistic superoxide dismutase from Aeropyrum pernix K1 – insights into the enzyme mechanism and stability pdf
... metal-binding site at the interface of the two domains, which consists of four side chains: two (His31 and His79) from the N-terminal domain and two (Asp165 and His169) from the C-terminal domain (Fig. ... Mn-reconstituted ApeSOD, the metal ion was five-coordinate in trigonal bipyramidal geometry (Fig. 3A). Three of the ligands, OD2 of Asp165, NE2 of His79 and...
Ngày tải lên: 14/02/2014, 22:20
Tài liệu Báo cáo khoa học: Solution NMR structure of an immunodominant epitope of myelin basic protein Conformational dependence on environment of an intrinsically unstructured protein doc
... proportional to the inverse of the average of the distance to the sixth power (<r )6 >), between the unpaired electron of the paramagnetic agent and the interacting nucleus. Thus, these agents ... along the horizontal axis was used to convert the left structure to the right structure. The N-ter- minus is at the left for every structure. The best-fit...
Ngày tải lên: 19/02/2014, 07:20
Tài liệu Báo cáo khoa học: Endotoxic activity and chemical structure of lipopolysaccharides from Chlamydia trachomatis serotypes E and L2 and Chlamydophila psittaci 6BC pdf
... 5 and 6) and assignment of all signals (Table 2) revealed that the carbohydrate structure of the major component of C. tra- chomatis E LPS consisted of three Kdo- and two GlcpN- residues. The 1 H-NMR ... have compared the endotoxic activities of three chlamydial LPS of known structure and defined purity. Whereas the chemical struc- tures of the LPS from C....
Ngày tải lên: 20/02/2014, 23:20