Báo cáo khoa học: Escherichia coli cyclopropane fatty acid synthase Mechanistic and site-directed mutagenetic studies potx

... Biochem. 271) Ó FEBS 2004 Escherichia coli cyclopropane fatty acid synthase Mechanistic and site-directed mutagenetic studies Fabienne Courtois, Christine Gue ´ rard, Xavier Thomas and Olivier Ploux Laboratoire ... UMR7613 CNRS, Universite ´ Pierre et Marie Curie, Paris, France Escherichia coli fatty acid cyclopropane synthase (CFAS) was overproduced and...

Ngày tải lên: 07/03/2014, 16:20

... 2004 MINIREVIEW Genetic defects in fatty acid b-oxidation and acyl-CoA dehydrogenases Molecular pathogenesis and genotype–phenotype relationships Niels Gregersen 1 , Peter Bross 1 and Brage S. Andresen 1,2 1 Research ... heart, liver and/ or the neuromuscular systems. Deficiencies in the transporters and enzymes involved in the oxidation of long-chain fatty acids are generally s...

Ngày tải lên: 23/03/2014, 12:20

... ubiquitously in a broad range of organisms from Escherichia coli to humans [1–3]. Two cyclophilins, E. coli CyPA and E. coli CyPB, have been identified [4,5], and at least five cyclophilins in mammals ... (mutant residue) and Leu165 on the b8 strand, and through Leu8 and Thr10 side chains on the b1 strand. In the crystal of free CyPB, a crystallographic twofold rotation axis i...

Ngày tải lên: 30/03/2014, 15:20

... (2002) Endocannabinoids in the immune system and cancer. Pros- taglandins Leukot. Essent. Fatty Acids 66, 319–332. 24. Cravatt, B.F. & Lichtman, A.H. (2003) Fatty acid amide hydro- lase: an emerging ... Wan,M.,Cravatt,B.F.,Ring,H.Z.,Zhang,X.&Francke,U. (1998) Conserved chromosomal location and genomic structure of human and mouse fatty- acid amide hydrolase genes and...

Ngày tải lên: 30/03/2014, 15:20

... are immiscible with water and that have low polar characteris- tics (hexane, diisopropyl ether, and 3-pentanone), and those that have polar properties and are water miscible (ethanol and acetonitrile). System ... hydration studies on dry proteins. There is a striking similarity between the water-adsorption properties of proteins in air and in organic solvents [13]. Early studie...

Ngày tải lên: 16/03/2014, 10:20

... Igor Twoodore, and Igore Twoodore. We estimate phonetic similarity between a source and target entity by computing Levenshtein and other distance metrics between the source entity and the closest ... of the English sentence. Different and possibly conflicting NE tags for candidate English and foreign sentence substrings according to the Wiki-based taggers and the Stanford tagger...

Ngày tải lên: 23/03/2014, 14:20

... of Escherichia coli PFK (PDB code 4pfk [12]). This was the most suitable template, given our interest in both catalytic and regulatory sites, among the various available structures of E. coli and ... muscle enzyme and the catalytic subunit of S. cerevisiae,andthePP i -depen- dent enzymes of E. histolytica, A. methanolica and P. freundenreichii. Sequences of yeast and human exp...

Ngày tải lên: 23/03/2014, 21:21

... MESR fellowship. References 1 Magalon A & Mendel RR (2008) Biosynthesis and insertion of the molybdenum cofactor. In EcoSal Escherichia coli and Salmonella: cellular and molecular biology (Bo ¨ ck A, Curtiss R III, ... NarG(1–15) and (B) NarG(1–28). A B Fig. 2. (A) Sequences of NarG(1–15) (left) and NarG(1–28) (right) and sequential assignments. Collected sequential NOEs ar...

Ngày tải lên: 16/02/2014, 14:20

... imper- meable to the Coenzyme A thioesters of long-chain fatty acids, these activated derivatives, which are synthesized from nonesterified fatty acids by fatty acyl-CoA synthetase on the cytosolic aspect ... Membrane transport of fatty acylcarnitine and free L -carnitine by rat liver microsomes Jason M. Gooding, Majid Shayeghi and E. David Saggerson Department of Biochemistry and...

Ngày tải lên: 16/03/2014, 16:20

... in the context of cutin and suberin studies [1,2]. These protective biopolymers are made mostly of hydroxyfatty acids and a,x-dicarbox- ylic acids esterified to each other and to glycerol. The hydroxyl ... Gerhardt B (1992) Fatty acid degradation in plants. Prog Lipid Res 31, 417–446. 53 Koiwai A & Matsuzaki T (1988) Hydroxy and normal fatty acid distribution in stigmas o...

Ngày tải lên: 22/03/2014, 16:21