Báo cáo khoa học: Insulin resistance in human adipocytes occurs downstream of IRS1 after surgical cell isolation but at the 1 level of phosphorylation of IRS1 in type 2 diabetes pot

... al. Insulin resistance in human adipocytes FEBS Journal 27 2 (20 05) 14 1 15 1 ª 20 04 FEBS 15 1 Insulin resistance in human adipocytes occurs downstream of IRS1 after surgical cell isolation but at the level ... n Insulin receptor 1. 1 1. 8 1. 1 1. 8 1. 1 1. 8 1. 1 1. 8 1. 1 1. 8 1. 1 1. 8 IRS1 0.6–0.7 0.6–0.7 1. 8 2. 0 1. 8 2. 0 1...

Ngày tải lên: 07/03/2014, 16:20

... is that of the task the user is performing (e.g., text editing vs. database querying); the name context is that of the other names being used; and the action context is that of the other ... features onto the semantic features of their referents. The role of syntactic and pragmatic features is analogous, but the issue there is not simply one of how simil...

Ngày tải lên: 31/03/2014, 17:20

... untreated control H77 21 cells;Ins,H7 721 cellstreatedwith2 n M insulin; LY2940 02, H77 21 cells treated with 15 l M LY2940 02; LY2940 02 + Ins, H77 21 cells treated with both LY2940 02 and insulin; Mock, ... elevate the cell adhesion of LY2940 02 treated cells and AS-PKB/H77 21 cells. Alteration in cell migration and invasion after treatment with insulin, LY2940 02 o...

Ngày tải lên: 21/02/2014, 00:20

... ins number: Na + K + ATPase EEA1 Calnexin 12 345678 910 111 21 3 14 40 60 80 10 0 12 0 Grb14 control i2i *** * * 10 0 12 0 0 20 1 2 3 4 5 6 7 8 9 10 11 12 13 14 ins 2 min ins 5 min Fraction number * 0 20 40 60 80 12 34 6 8 910 111 21 3 14 * *** * * *** *** 12 345678 910 111 21 3 14 Fig. 1. ... ins Grb14 50 15 0 20 0 25 0 10 0 * *** *** – ins + ins 0 600 800...

Ngày tải lên: 18/02/2014, 18:20

... (19 89) Internalization and activation of the rat liver insulin receptor kinase in vivo. J Biol Chem 26 4, 12 9 31 12 940. 35 Ahmad F & Goldstein BJ (19 97) Functional association between the insulin ... receptors. Role of endosome-asso- ciated phosphotyrosine phosphatase(s). J Biol Chem 26 7, 11 21 5 11 2 21 . N. Bilodeau et al. Regulation of DPP IV trafficking FEB...

Ngày tải lên: 19/02/2014, 07:20

... nitrotyrosine in colo- nic epithelium in inflammatory bowel disease. Gastro- enterology 11 1, 8 71 885. ILT2 nitration in the binding domain A. Dı ´ az-Lagares et al. 424 2 FEBS Journal 27 6 (20 09) 423 3– 424 3 ... 18 98 19 08. A. Dı ´ az-Lagares et al. ILT2 nitration in the binding domain FEBS Journal 27 6 (20 09) 423 3– 424 3 ª 20 09 The Authors Journal compilation ª 20...

Ngày tải lên: 07/03/2014, 02:20

... 4A). A B 0 1 2 3 4 5 6 7 Control 2 20 20 0 20 00 Insulin (n M ) relative expression 0 1 2 3 4 5 6 Control 1 2 4 6 16 24 Insulin (h) relative expression C D EF Fig. 1. Insulin stimulates heme oxygenase -1 (HO -1) protein and ... administered to establish the role of protein synthesis in insulin- induced HO -1 expression (Fig. 2B,C). CHX abrogated HO -1 protei...

Ngày tải lên: 07/03/2014, 12:20

... mLámin )1 . The two uH1A fragments (Lys1 52 Lys 222 and Lys167±Lys 222 ) we re eluted in peaks 2 a nd 5, respectively. Thr ee histone H1D fragments (A179±K 21 2 , K175±K 21 2 and T166±K 21 2 ) were found in peaks ... Lys1 52 Lys 222 (75 27  1 Da) and Lys167±Lys 222 (6 023  1 Da). Tandem MS (MS/MS) of the 7.5 kDa and 6.0 kDa frag- ments indicated that the post-translati...

Ngày tải lên: 08/03/2014, 10:20

... portion of the string as soon as that portion be- gins, or delays the analysis, i.e., determines structure only after further material of the string is received. The other feature is whether the ... that during the period in which that determination is delayed, other attachment pos- sibilities of the constituent into higher -level structures (which are themselv...

Ngày tải lên: 08/03/2014, 18:20

... al. TSC1 ⁄ TSC2 distribution with IGF -1 stimulation FEBS Journal 27 7 (2 010 ) 21 8 0– 21 9 1 ª 2 010 The Authors Journal compilation ª 2 010 FEBS 21 9 1 Insulin like growth factor -1- induced phosphorylation ... stimulation FEBS Journal 27 7 (2 010 ) 21 8 0– 21 9 1 ª 2 010 The Authors Journal compilation ª 2 010 FEBS 21 8 3 Fig. 2. IGF -1 induced subcellular distribut...

Ngày tải lên: 15/03/2014, 11:20