Báo cáo khoa học: Effect of priming on activation and localization of phospholipase D-1 in human neutrophils potx

... N-formylmethionyl-leucyl- phenylalanine stimulation of human neutrophils. Biochem. J. 325, 581–585. 2764 K. A. Cadwallader et al.(Eur. J. Biochem. 271) Ó FEBS 2004 Effect of priming on activation and localization of phospholipase ... accumulating within the first 5 min of stimulation. Effect of PI3-kinase and ARF inhibitors on O À 2 and PLD activation Sele...

Ngày tải lên: 07/03/2014, 15:20

... typical unfolding experiment, two stock solutions of PrP at identi- cal protein concentrations (5 lm) were prepared: one in buffer only (native protein) and one in buffer containing a high concentration of ... pro- tein should provide insight into the process of prion conversion, and represent a major step forward in our understanding of the misfolding and aggregation of...

Ngày tải lên: 18/02/2014, 17:20

... is being formed, and has also been reported for the concerted action of Bax and tBid [10]. Concluding remarks In summary, peptides corresponding to natural sequences of Bax and encompassing individual ... curves, indicative of co-operativity, with in exion points corresponding to peptide concentra- tions giving 50% of maximum activity (IC 50 ). With LUVs made of PtdCho at 6...

Ngày tải lên: 19/02/2014, 07:20

... several different conditions are shown in Table 1. The rates o f inactivation and aggregation d epend on the protein Fig. 1. Thermal inactivation and aggregation of lysozyme in the presence of additives. ... rate-limiting step in both inactivation and aggregation of lysozyme by heat treatment. As the d ata points were well fitted to the single-exponential eq uation, the hea...

Ngày tải lên: 19/02/2014, 16:20

... number of intracellular roles: it can alter gene expression, in uence the rate of cell proliferation and differ- entiation, and inhibit apoptosis in a manner independent of urokinase inhi- bition. ... several ARE binding proteins, including the stabilizing protein HuR [86] and the mRNA destabilizing protein tristetr- aprolin (TTP) [87]. HuR is a member of the Hu family of m...

Ngày tải lên: 20/02/2014, 02:21

... functional characterization of the TLP from various organisms, and the evolution of TLP and transthyretin. The identification of TLPs and transthyretins in nature The evolution of transthyretin and ... involved in the oxidation of uric acid to allantoin. Certainly, the co -localization of these proteins in the peroxisomes of metazoan and plant species, and the...

Ngày tải lên: 07/03/2014, 00:20

... macrophages, suggesting that fractalkine is involved in neuron– microglia signalling [178]. In fact, this chemokine participates in leukocyte migration and in the activa- tion and chemoattraction of microglia into ... beneficial effects by promoting vasodilata- tion, whereas NO produced during later stages of injury by overactivation of neuronal NOS and de novo expression...

Ngày tải lên: 07/03/2014, 03:20

... aromatic amino acids (including, kynurenine, phenylalanine, tryptophan and tyrosine); sulfur containing amino a cids (including, methionine an d cysteine) and other aliphatic a mino acids (including, ... is efficient in catalyzing the transamination of a number of amino acids, including glutamine, phenylalanine, leucine, kynurenine, methionine, tyrosine, histidine, cys- teine, and...

Ngày tải lên: 07/03/2014, 16:20

... remains one of the most infectious diseases in the third world with abou t 500 million infections and over one million deaths per year [1]. In the face of increasing threats by resurgent infections ... recombinant protein and results in the addition of a short noncleavable His tag sequence at its N-terminus. Cloning resulted in incorporation of an a ddi- tional 18 (MRGSHHH...

Ngày tải lên: 16/03/2014, 18:20

... serving as conceptual intro- duction to the whole article. Introductory example The example is concerned with insulin signaling, and is inspired by the developments in [12]. Insulin signaling occurs ... example, in the evaluation of the importance of re-cycling of STAT5 [9–11], a pri- mary argument for the importance of this recycling was based on a model based analysis of t...

Ngày tải lên: 23/03/2014, 06:20