Báo cáo khoa học: MR solution structure of the precursor for carnobacteriocin B2, an antimicrobial peptide fromCarnobacterium piscicola Implications of the a-helical leader section for export and inhibition of type IIa bacteriocin activity pdf
Báo cáo khoa học: MR solution structure of the precursor for carnobacteriocin B2, an antimicrobial peptide fromCarnobacterium piscicola Implications of the a-helical leader section for export and inhibition of type IIa bacteriocin activity pdf
... NMR solution structure of the precursor for carnobacteriocin B2, an antimicrobial peptide from Carnobacterium piscicola Implications of the a-helical leader section for export and inhibition of ... establish the preferred geometry of the precursor. We now report the chemical synthesis, bio- chemical production, and solution structure...
Ngày tải lên: 07/03/2014, 15:20
Báo cáo khoa học: Monomeric solution structure of the helicase-binding domain of Escherichia coli DnaG primase pdf
... a continu- ous strand [1]. During DNA replication, a helicase sep- arates the double-stranded DNA into single strands, and replication of the leading strand and synthesis of the Okazaki fragments ... Stereo views of the solution and crystal structures of DnaG-C. (A) Superposi- tion of the backbone atoms of residues 447–581 of the 20 NMR conformers of DnaG-C...
Ngày tải lên: 16/03/2014, 12:20
Báo cáo khoa học: NMR solution structure of Cn12, a novel peptide from the Mexican scorpion Centruroides noxius with a typical b-toxin sequence but with a-like physiological activity doc
... of discriminating between Na + -channel isoforms of the same organism (e.g. the rat brain isoform rNa V 1.1 is 10-fold more sensitive to the action of the a Na-ScTx Lqq5 than the cardiac isoform ... knew that the remaining disulfide bridges were between Cys25 and Cys45 and Cys29 and Cys47, or conversely between Cys25 and Cys47 and Cys29 and Cys45. The sequences...
Ngày tải lên: 23/03/2014, 12:20
Báo cáo khoa học: Atomic-resolution structure of reduced cyanobacterial cytochrome c6 with an unusual sequence insertion pot
... inhibitor structure (3.44–3.58 A ˚ ). The stability of Tyr56 may be important for the conformation of Gln57, and consequently for tuning the redox potential of the protein. Phe68 forms part of a conserved ... because of its very high content (36%) of the smallest resi- dues (glycine and alanine). The structure reveals that the overall fold of the prot...
Ngày tải lên: 23/03/2014, 05:22
Báo cáo khoa học: Change in structure of the N-terminal region of transthyretin produces change in affinity of transthyretin to T4 and T3 pdf
... demonstration of the rela- tionship between the evolution of the primary structure of the N-terminal regions of TTR and the biological function of TTR. Results Synthesis of recombinant human TTR In the crocodile, ... 2006) doi:10.1111/j.1742-4658.2006.05404.x The relationship between the structure of the N-terminal sequence of trans- thyretin (TTR) and...
Ngày tải lên: 23/03/2014, 10:21
Báo cáo khoa học: NMR solution structure and function of the C-terminal domain of eukaryotic class 1 polypeptide chain release factor pdf
... alignment of eRF1. Fig. S11. The Ramachandran map plot (/ and w tor- sion angles for the protein backbone) of all 24 con- formers of the NMR families of solution structures of the closed and open conformers ... conformer and near Glu365 and Glu367 in the closed conformer, and these polar interactions may play an important role in the stabil- ization of...
Ngày tải lên: 06/03/2014, 11:20
Tài liệu Báo cáo khoa học: Salt-induced formation of the A-state of ferricytochrome c – effect of the anion charge on protein structure docx
... c. The Soret absorbance band is red-shifted (more pro- nounced in the case of the K13N mutant), and the absorbances at 497 and 528 nm, in the visible region, are inverted, whereas the CT band ... influenced by the type of anion in solution [17,18]. Because structural information on partially folded forms is important for a deeper understanding of the folding mec...
Ngày tải lên: 19/02/2014, 05:20
Báo cáo khoa học: Hexameric ring structure of a thermophilic archaeon NADH oxidase that produces predominantly H2O pot
... conditions as used for the wild -type. The results showed that the C122A mutant had similar NADH and NADPH oxi- dase activity to that of the wild -type protein; however, the C45A mutant and the double ... NADH and NADPH as electron donors. In addition, the activity and prod- uct assays of the wild -type and mutants showed that Cys45 is the active site r...
Ngày tải lên: 07/03/2014, 04:20
Báo cáo khoa học: X-ray structure of peptidyl-prolyl cis–trans isomerase A from Mycobacterium tuberculosis potx
... by enzymes in the new group is also likely to resemble that of the human PpiA and PpiB and most others. In the binding site of the B. malayi Ppi,theequivalentofAla118is Fig. 4. Sequence alignment. The ... target. Acknowledgements The authors thank Markus Dalin for help with cloning and i nitial crystallization experiments, Andrea Wilnerz on and Jimmy Lindbe rg for...
Ngày tải lên: 16/03/2014, 18:20
Báo cáo khoa học: X-ray structure of glucose/galactose receptor from Salmonella typhimurium in complex with the physiological ligand, (2R)-glyceryl-b-D-galactopyranoside pdf
... to the physiologically relevant ligand, (2R)-glyceryl-b-d-galactopyranoside, solved by molecular replace- ment, and refined to 1.87 A ˚ resolution with R and R-free values of 17% and 22%. The structure ... lactose, is the natural substrate of the system. Thus, GGal taken up by the Mgl trans- porter will induce expression of the lac operon, and so promote further upt...
Ngày tải lên: 23/03/2014, 04:21