Báo cáo khóa học: Surface nucleolin participates in both the binding and endocytosis of lactoferrin in target cells potx

... 2003 Nucleolin is a cell surface lactoferrin -binding site (Eur. J. Biochem. 271) 317 Surface nucleolin participates in both the binding and endocytosis of lactoferrin in target cells Dominique ... the iron -binding hTf had no effect. On the other hand, bLf inhibited the binding of HB-19 to cells. In accordance with the involvement of both...

Ngày tải lên: 07/03/2014, 15:20

... implemented, and the form of its surface presentation is also being refined. Foundations in linguistic theory We are committed to active recognition of the mutual benefit of machine translation and ... enabling the user to extend the available working vocabulary without bilingual knowledge. The dictionaries, the user, and the system The dictionary creat...

Ngày tải lên: 01/04/2014, 00:20

... within the same cell. Furthermore, in cells expressing either the double or single mutants, we tended to see a decrease in the number of cells with the ability to reduce transferrin binding compared ... that cells expressing wild-type HFE displayed a striking decrease in cell -surface bind- ing of transferrin, and that little or no reduction in transferrin bind...

Ngày tải lên: 06/03/2014, 22:21

... central intermediate in the de novo and salvage biosynthesis of pyrimidine, purine and pyridine nucleotides as well as in the biosynthesis of the amino acids histidine and tryptophan [1,2]. In addition, ... activity obtained in the absence of these nucleotides. The activity in the presence of 5.0 m M UTP was only 20% of that in the absence of UTP, i...

Ngày tải lên: 23/03/2014, 13:20

... a-helix containing the peroxi- somal targeting signal) to the bab motif, known as the dinucleotide -binding domain [2], and on the other side to the long loop following the b-strand I7 containing Trp243 ... titrating the apoprotein with increasing amounts of FAD and following the decrease in protein fluorescence: a K d value of 0.37 and 0.035 lm of the apoprote...

Ngày tải lên: 30/03/2014, 11:20

... located in independent domains (a b-domain for the N-terminal cluster and an a-domain for the C-terminal cluster). In the absence of metals, apo-thionein (apo-T) is predominantly unstruc- tured and ... First, the metal binding is thermodynamically relatively stable, with the following order Cu(I)>Cd(II)>Zn(II). The cluster structure raises the possibility of...

Ngày tải lên: 16/02/2014, 15:20

... most of the AtERFs exhibited similar stability in binding to either the GCC or the DRE motif. The most remarkable feature arising from the competition binding assay was the consistency of the binding ... Competition binding assay of the ERF–DNA complex. The binding complex of the ERFs and their binding DNAs were incu- bated together with 0, 0.001, 0...

Ngày tải lên: 18/02/2014, 13:20

... consisting of helices a2 and a3 at the N-termi- nus. The core domain (a5toa10) contains the tc bind- ing pocket and the dimerization motif. Both domains are connected by helix a4, and their interface ... affinities and positive cooperativity. Thus, mutations in this interface can in uence DNA binding as well as effector binding, albeit both ligand binding sites ar...

Ngày tải lên: 20/02/2014, 01:20

... answers each. The total cost of producing the corpus was about $350, consisting of $310 paid in workers rewards and $40 in Mechanical Turk fees, including all the trials conducted during the devel- opment ... documents). The source of Wik- iXML is the English part of the Wikipedia XML Corpus by Denoyer and Gallinari (2006). In the original data some of the...

Ngày tải lên: 20/02/2014, 09:20

... which do not contain an in- put keyword. Since the extraction module (see Sec- tion 2.3) analyzes the usage of the input term in re- trieved pages, pages not containing the term are of no use for ... FDDI, d) token ring In the autumn of 1999, out of 80 questions, the num- ber of the first and second types were 22 and 18, re- spectively. 4.3 Implementing a QA s...

Ngày tải lên: 20/02/2014, 18:20