Báo cáo khoa học: The hyperfluidization of mammalian cell membranes acts as a signal to initiate the heat shock protein response pptx
Báo cáo khoa học: The hyperfluidization of mammalian cell membranes acts as a signal to initiate the heat shock protein response pptx
... activation of kinases such as Akt has been shown to increaseHSF1 activity. Enhanced Ras maturation by heat stresswas associated with a heightened activation of extra-cellular signal- regulated ... and heat shock response G. Balogh et al.6086 FEBS Journal 272 (2005) 6077–6086 ª 2005 The Authors Journal compilation ª 2005 FEBS The hyperfluidization of mammalian cell membranes acts as a signal ... element of the heat shock response in mammalian cells. Whereas the synthesis of HSP-70 has been dem-onstrated to be promoted by an increase in [Ca2+]i, the overexpression of HSP-70 attenuates...
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Tài liệu Báo cáo khoa học: Efficient killing of SW480 colon carcinoma cells by a signal transducer and activator of transcription (STAT) 3 hairpin decoy oligodeoxynucleotide – interference with interferon-c-STAT1-mediated killing pdf
... participates ingrowth regulation of human breast carcinoma cells.Oncogene 20, 2499–2513.9 Kanda N, Seno H, Konda Y, Marusawa H, Kanai M,Nakajima T, Kawashima T, Nanakin A, Sawabu T,Uenoyama Y ... XY(1997) Activation of the STAT signaling pathway cancause expression of caspase 1 and apoptosis. Mol Cell Biol 17, 5328–5337.26 Lin Q, Lai R, Chirieac LR, Li C, Thomazy VA, Gram-matikakis I, Rassidakis ... SW480). The hairpin STAT3 decoy ODN inhibits the transcriptional activity of STAT3 and colocalizeswith STAT3 to the cytoplasm of SW480 cells The transcriptional activity of STAT3 after treatmentof...
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Báo cáo khoa học: Molecular identification of adrenal inner zone antigen as a heme-binding protein potx
... 428–443.14 Hand RA, Jia N, Bard M & Craven RJ (2003)Saccharomyces cerevisiae Dap1p, a novel DNA damage response protein related to the mammalian membrane-associated progesterone receptor. Eukaryot ... reticularis zones of the rat adrenal, was previously found to be identical with a protein vari-ously named 25-Dx and membrane-associated progesterone receptor. IZAwas purified as a glutathione ... pSVL-fLuc plasmid was cotransformed with hIZA1s expression vectors and Renilla luciferase vector as an internal standard. The promoter activity of pSVL was normalized to Renilla luciferase activity. (C)...
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Báo cáo khoa học: X-ray structure of glucose/galactose receptor from Salmonella typhimurium in complex with the physiological ligand, (2R)-glyceryl-b-D-galactopyranoside pdf
... lac operon, i.e. b-galacto-sidase, the lactose transporter and thiogalactosideKeywordsgalactose uptake; glucose ⁄ galactose-binding protein; glyceryl galactoside; lactose uptake;Salmonella ... (hereafter referred to as GGal) is found naturally as the polar head group of plant glycolipids. An estimated 16.6% of the totallipids in runner bean leaves represents GGal [8], and a similar abundance ... Journal compilation ª 2009 FEBStransacetylase [10]. The (2R), and not the (2S), diaste-reomer is formed by E. coli b-galactosidase duringtransfer of the galactosyl residue from any galactosyldonor...
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Tài liệu Báo cáo khoa học: Expression and secretion of interleukin-1b, tumour necrosis factor-a and interleukin-10 by hypoxia- and serum-deprivation-stimulated mesenchymal stem cells Implications for their paracrine roles ppt
... solution were applied to the wells. The absorbance of the samples was measured at450 nm using a microplate reader.Statistical analysisData are expressed as the mean ± SEM. Differencesamong groups ... disease is a life-threatening conditionthat may cause sudden cardiac failure and death.Many researchers have investigated cell transplantation as an alternative treatment for heart disease. ... which are dependent on activation of the NF-jBpathway.Hypoxia⁄SD-induced IL-1b and TNF -a transcriptiondepend on the extracellular signal- regulatedkinase pathway The extracellular signal- regulated...
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Tài liệu Báo cáo khoa học: Cloning and characterization of CBL-CIPK signalling components from a legume (Pisum sativum) ppt
... (degenerate forward)25¢-ACAAA (A ⁄ C )A( A ⁄ G) (A ⁄ G ⁄ T )A( C ⁄ T) (A ⁄ C ⁄ G)ACACCACAAGACC)3¢ PsCIPK (degenerate reverse)35¢-CTTAT(C ⁄ G)AACAAGGAA (A ⁄ C)AATTTC-3¢ PsCBL (degenerate forward)45¢-GTATCAGCTTC(C ... forward)45¢-GTATCAGCTTC(C ⁄ T)TCAAATGTC-3¢ PsCBL (degenerate reverse)55¢-CCATCACAAGAAACTAGAGAAAC-3 PsCIPK (5¢UTR forward)65¢-TTAAGTACTATAAAT-ACACAGCCTA-3¢ PsCIPK (3¢UTR reverse)75¢-CGAGCTCACTGCCTCTCAAC-3¢ PsCBL ... kinase assayPhosphorylation was measured as the incorporation of radioactivity from c-32P-ATP into the PsCIPK (auto-phosphorylation) or into the substrate proteins. The puri-fied recombinant...
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Báo cáo khoa học: Post-ischemic brain damage: NF-jB dimer heterogeneity as a molecular determinant of neuron vulnerability pdf
... factor-2, signal transducer and activator of tran-scription 3 and nuclear factor-kappaB (NF-j B) [1].NF-jB is a key regulator of both inflammation and cell death and has been proposed as suitable target ... NF-jBin the synaptic regions has also suggested that NF-jBmight be regarded as a signal transducer that transmitstransient synaptic signals to the nucleus and has a rolein behaviour, learning and ... originallatent state. Two different intracellular pathways acti-vate NF-jB, namely the ‘classic’ pathway and the ‘alternative’ pathway, which result in the release of NF-jB from its inhibitors and in the...
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Báo cáo khoa học: Phenylalanine-independent biosynthesis of 1,3,5,8-tetrahydroxyxanthone A retrobiosynthetic NMR study with root cultures of Swertia chirata docx
... chirata joins the growing list of secondary plant meta-bolites that are derived from an early shikimate derivative as opposed to a pathway via phenylalanine and cinnamate. A hypothetical mechanism ... the 13C-NMRspectra was integrated separately. The relative fractions of each respective satellite pair in the total13C-NMR signal integral of a given carbon atom were then calculated(%13C13C in Table ... phos-phoenolpyruvate (1) by dissection of the phenylalaninelabelling patterns according to the shikimate pathway, the universal source of the carbon skeletons of aromatic acids. The labelling patterns of...
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Báo cáo khoa học: "Feature-Rich Part-of-speech Tagging for Morphologically Complex Languages: Application to Bulgarian" docx
... Dagan, editors, Fourth Workshop on VeryLarge Corpora, pages 133–142, Copenhagen, Den-mark.Aleksandar Savkov, Laska Laskova, Petya Osenova,Kiril Simov, and Stanislava Kancheva. 2011. A web-based ... that they are also 100% accurate on the test and on the development dataset.Note that some of the rules are dependent onothers, and thus the order of their cascaded appli-cation is important. ... Canada.Nizar Habash and Owen Rambow. 2005. Arabic to- kenization, part -of- speech tagging and morpholog-ical disambiguation in one fell swoop. In Proceed-ings of the 43rd Annual Meeting of the Associa-tion...
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Báo cáo khoa học: X-ray structure of peptidyl-prolyl cis–trans isomerase A from Mycobacterium tuberculosis potx
... and nativePAGE (PhastSystemTM, Amersham Biosciences).Assay The activity of MtPpiA was evaluated u sing a spectropho-tometric assay [ 12], in which the cisfitrans isomerizationis measured ... show an rmsd of approxi-mately 1.6 A ˚from that of Mt PpiA, when the C a atoms arecompared using a cut-off of 3.5 A ˚(with 88% of the Casmatching). This is significantly larger than the ... MtPpiA with confidence. Thus the affinity of MtPpiA for the HAGPIA peptide may beexpected to be of the same order of magnitude as the concentration at which it was present in the crystallizationsolution...
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