Báo cáo khoa học: The variable C-terminal extension of G-protein-coupled receptor kinase 6 constitutes an accessorial autoregulatory domain ppt
Báo cáo khoa học: The variable C-terminal extension of G-protein-coupled receptor kinase 6 constitutes an accessorial autoregulatory domain ppt
... only enhance the hydrophobicity and thereby strengthen the membrane association of GRK6-A, but also increase the kinase catalytic activity of the pro- tein. Along the same lines, the C-terminal ... consisting of a single resi- due, D 560 , and the sequence between residues S 566 and L5 76, and an intervening stimulatory element. Discussion We expressed the four var...
Ngày tải lên: 07/03/2014, 12:20
Báo cáo khoa học: The noncatalytic C-terminus of AtPOLK Y-family DNA polymerase affects synthesis fidelity, mismatch extension and translesion replication ppt
... On the other hand, truncation of the C-terminal domain increases the bypass efficiency and decreases the efficiency of A insertion, thus reducing mutagenic translesion synthesis. Taken together these results ... signal, and a candidate PCNA-interaction domain. To better understand the role of the C-terminal domain of this Y-family DNA polymerase during DNA synthesi...
Ngày tải lên: 16/03/2014, 10:20
Tài liệu Báo cáo khoa học: The tandemly repeated domains of a b-propeller phytase act synergistically to increase catalytic efficiency doc
... pH (6. 0–8.0) and at low temperatures (0–35 °C). We focus on the function and relationship of the two single domains. Additionally, the possibility that fusion of the PhyH N-terminal domain to other ... Ca 2+ increased the thermal stability of PhyH and PhyH-DII. After incubation at 60 °C for 30 min, both enzymes retained > 70% of their initial activity in the presen...
Ngày tải lên: 14/02/2014, 15:20
Tài liệu Báo cáo khoa học: The PA-TM-RING protein RING finger protein 13 is an endosomal integral membrane E3 ubiquitin ligase whose RING finger domain is released to the cytoplasm by proteolysis ppt
... (2003) Gamma-secretase cleavage and binding to FE65 regu- late the nuclear translocation of the intracellular C-ter- minal domain (ICD) of the APP family of proteins. Biochemistry 42, 66 64 66 73. 63 Marambaud P, ... protein-associated domain and the RING domain from the mem- brane. By analyzing microsomes, we showed that the ectodomain is shed into the lumen of...
Ngày tải lên: 18/02/2014, 08:20
Tài liệu Báo cáo khoa học: The thioredoxin-independent isoform of chloroplastic glyceraldehyde-3-phosphate dehydrogenase is selectively regulated by glutathionylation docx
... [20]. On the other hand, the activity of the purified recombinant C153S mutant was similar to that of the wild-type protein (data not shown), and the kinetics of inactivation in the presence of 1 ... might be the target of glutathionylation or % Intensity B +GSSG dithiothreitol 364 00 363 53 366 63 368 00 37200 380003 760 0 360 00 364 00 368 00 37200 380003 760 0...
Ngày tải lên: 19/02/2014, 05:20
Tài liệu Báo cáo khoa học: "The grapho-phonological system of written French: Statistical analysis and empirical validation" pdf
... implementations of the dual-route theory (Coltheart et aL, 1993). The "central dogma" of this theory is that the performance of human subjects on pseudowords is accounted for by an analytic ... human naming performance is influenced by the frequency of graphemic units in the language and by the predictability of their mapping to phonemes. We argue th...
Ngày tải lên: 20/02/2014, 19:20
Tài liệu Báo cáo khoa học: The isolation and characterization of cytochrome c nitrite reductase subunits (NrfA and NrfH) from Desulfovibrio desulfuricans ATCC 27774 Re-evaluation of the spectroscopic data and redox properties ppt
... membrane topology, solely bound to the membrane by the NrfH transmembrane subunit. Therefore, can easily detach to the periplasm or become partly solubilized during breaking up of the cells. In other ... The complex dissociates into an intense band of 61 kDa (NrfA) and a band of weak intensity of 19 kDa (NrfH), confirming its hetero-oligomeric nature (Fig. 1, lane 1). Howe...
Ngày tải lên: 21/02/2014, 00:20
Tài liệu Báo cáo khoa học: "The Structure and Process of Talking About Doing" pdf
... i can be ruled cut. Therefore-do actlon A i, Here is an- example of this Mind of argument struSture: • %f Z put a cannibal on, then he gee• hack and the guys on the other side of the ... violate the constraints or the task. Host of these errors occur on the side away frm their current "point st view", even theuah their point of view changes From one ph...
Ngày tải lên: 21/02/2014, 20:20
Báo cáo khoa học: The N-terminal region of the bacterial DNA polymerase PolC features a pair of domains, both distantly related to domain V of the DNA polymerase III s subunit ppt
... domain and the additional N- and C-terminal regions in PolC and DnaE, respec- tively. The PolC proofreading 3¢–5¢ exonuclease domain is inserted into the PHP domain and is an integral part of the ... sin- gle-stranded DNA has indeed been demonstrated for the E. coli DnaE OB domain [12, 16] . The very N-ter- minal region of PolC and the C-terminal domain of...
Ngày tải lên: 05/03/2014, 23:20
Báo cáo khoa học: The oleic acid complexes of proteolytic fragments of a-lactalbumin display apoptotic activity pdf
... 385–397. 36 Yang F Jr, Zhang M, Chen J & Liang Y (20 06) Struc- tural changes of a-lactalbumin induced by low pH and oleic acid. Biochim Biophys Acta 1 764 , 1389–13 96. 37 Zhang M, Yang F Jr, Yang ... molecu- lar mechanism of interaction and physicochemical properties of the OA complex are not understood, and neither are the mechanisms and cellular events involved in the t...
Ngày tải lên: 06/03/2014, 09:22