Báo cáo khoa học: Structure ⁄function analysis of spinalin, a spine protein of Hydra nematocysts doc

Báo cáo khoa học: Structure ⁄function analysis of spinalin, a spine protein of Hydra nematocysts doc

Báo cáo khoa học: Structure ⁄function analysis of spinalin, a spine protein of Hydra nematocysts doc

... the Golgi apparatus. During this process, the external tubule is assembled at the apical end of the capsule and in a later stage invag- inates into the capsule matrix and spines are assembled in ... isorhizas appear to function as barbs binding the discharged nematocyst to prey or to the substrate. Spinalin is a 24-kDa pro- tein that is a constituent of spines and opercula of Hyd...
Ngày tải lên : 07/03/2014, 12:20
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Báo cáo khoa học: Structure–function analysis of the filamentous actin binding domain of the neuronal scaffolding protein spinophilin pot

Báo cáo khoa học: Structure–function analysis of the filamentous actin binding domain of the neuronal scaffolding protein spinophilin pot

... the pathway constituents that regulate actin bind- ing through phosphate signalling are unknown. We have undertaken a systematic and detailed struc- tural and functional analysis of the ABD of ... signal-regulated kinase-2; F-actin, filamentous actin; GST, glutathione S-transferase; IUP, intrinsically unstructured protein; MBP, maltose binding protein; PKA, protein kinase -A; PP1,...
Ngày tải lên : 16/03/2014, 06:20
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Báo cáo khoa học: Structure–function relationship of novel X4 HIV-1 entry inhibitors – L- and D-arginine peptide-aminoglycoside conjugates pptx

Báo cáo khoa học: Structure–function relationship of novel X4 HIV-1 entry inhibitors – L- and D-arginine peptide-aminoglycoside conjugates pptx

... posttranslational modifications, and internalization in viral-cell fusion and as targets for entry inhibitors. Biochim Biophys Acta 1614, 51–61. 7 Tachibana K, Hirota S, Iizasa H, Yoshida H, Kawaba- ta ... and T140, we are now also exploring their capacity to serve as anti-metastatic agents. Aminoglycosides are known as antibiotics; thus, exploring the efficacy of APACs against microbial path...
Ngày tải lên : 16/03/2014, 06:20
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Tài liệu Báo cáo khoa học: Verprolin function in endocytosis and actin organization Roles of the Las17p (yeast WASP)-binding domain and a novel C-terminal actin-binding domain doc

Tài liệu Báo cáo khoa học: Verprolin function in endocytosis and actin organization Roles of the Las17p (yeast WASP)-binding domain and a novel C-terminal actin-binding domain doc

... domain Thirumaran Thanabalu 1,2 , Rajamuthiah Rajmohan 2 , Lei Meng 2 , Gang Ren 4,5 , Parimala R. Vajjhala 4 and Alan L. Munn 1,3,4,6 * 1 Institute of Molecular and Cell Biology, A* STAR Biomedical Science ... polyclonal GFP-spe- cific antiserum was a gift from J. Kahana and P. Silver (Dana Farber Cancer Center, Boston, MA). The anti-actin mAb was MAB1501 from Chemicon International (Tem...
Ngày tải lên : 18/02/2014, 16:20
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Tài liệu Báo cáo khoa học: Marine toxins and the cytoskeleton: a new view of palytoxin toxicity ppt

Tài liệu Báo cáo khoa học: Marine toxins and the cytoskeleton: a new view of palytoxin toxicity ppt

... Ishida S, Inoue A, Kan Y & Yasumoto T (1995) Palytoxin analogs from the dino- flagellate Ostreopsis siamensis. J Am Chem Soc 117, 5389–5390. 5 Taniyama S, Arakawa O, Terada M, Nishio S, Takatani ... MINIREVIEW Marine toxins and the cytoskeleton: a new view of palytoxin toxicity M. Carmen Louzao, Isabel R. Ares and Eva Cagide Departamento de Farmacologia, Facultad de Veterinaria, Unive...
Ngày tải lên : 18/02/2014, 14:20
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Tài liệu Báo cáo khoa học: "Exploiting Readymades in Linguistic Creativity: A System Demonstration of the Jigsaw Bard" docx

Tài liệu Báo cáo khoa học: "Exploiting Readymades in Linguistic Creativity: A System Demonstration of the Jigsaw Bard" docx

... comple- ment of adjectival properties used by Veale and Hao (2007), we harvest all instances of the patterns “as ADJ and * as” and “as * and ADJ as” from Google, noting the combinations that are found and their ... respec- tively, such that Adj A 1 and Adj A 2 are mutu- ally reinforcing. The combination is indexed on Adj A 1 +Adj A2 . Example: “as dark and sophisticated as a...
Ngày tải lên : 20/02/2014, 05:20
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Báo cáo khoa học: Structural and functional evidence for a singular repertoire of BMP receptor signal transducing proteins in the lophotrochozoan Crassostrea gigas suggests a shared ancestral BMP/activin pathway docx

Báo cáo khoa học: Structural and functional evidence for a singular repertoire of BMP receptor signal transducing proteins in the lophotrochozoan Crassostrea gigas suggests a shared ancestral BMP/activin pathway docx

... tract, gills, heart and labial palp) including female gonads (oocytes), and from various stages of embryonic and larval devel- opment (blastula, gastrula, trochophore larvae, D lar- vae, 7 and ... method of the PAUP package. The percentage recovery of the branch in 1000 bootstrap replications is indicated. ActR2b Carassius auratus (ABB58749)Daf-1 Caenohabditis elegans (P20792), Daf-4 Ca...
Ngày tải lên : 07/03/2014, 21:20
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Báo cáo khoa học: "The Human Language Project: Building a Universal Corpus of the World’s Languages" pptx

Báo cáo khoa học: "The Human Language Project: Building a Universal Corpus of the World’s Languages" pptx

... purposes a perfectly adequate meaning rep- resentation. That is, we view machine translation as an approximation to language understanding. Here is another way to put it. One measure of adequacy of a ... primary form, but the percentage of documents with man- ual annotation, or manually corrected annotation, decreases at increasingly fine-grained levels of an- notation. Where manua...
Ngày tải lên : 16/03/2014, 23:20
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Báo cáo khoa học: Alpha 1-antichymotrypsin/SerpinA3 is a novel target of orphan nuclear receptor Nur77 potx

Báo cáo khoa học: Alpha 1-antichymotrypsin/SerpinA3 is a novel target of orphan nuclear receptor Nur77 potx

... 5¢-ATGGTGGGAATGGGTCAGAAG-3¢ and 5¢-CA CGCAGCTCATTGTAGAAGG-3¢. Another primer pair used for SerpinA3 was ACTas5-ACTas3: 5¢-GAATCC ACCAGCTACATCCA-3¢ and 5¢-GTGCCCTCCTCAAA TACATCA-3¢. Western blot assay The cells ... pcDNA3.1-GST-Nur77 plasmid. pSilencer-shNur77 was prepared by overlapping strategy with primers 5¢-gacGGATCCgcagtccagccatgctccttt caagagaaggagcatg-3¢ (with BamHI), 5¢-cggAAGCTTtATC...
Ngày tải lên : 23/03/2014, 07:20
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Báo cáo khoa học: "Using Reinforcement Learning to Build a Better Model of Dialogue State" pdf

Báo cáo khoa học: "Using Reinforcement Learning to Build a Better Model of Dialogue State" pdf

... of not having enough data to train on. Our results here indicate that a small training corpus is actually acceptable to use in a M DP framework as long as the state and action features are pruned ... good state and action fea- tures as an initial policy to bootstrap a RL-based dialoge system. They found that their automati- cally created state and action seeds outperformed hand-crafte...
Ngày tải lên : 24/03/2014, 03:20
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