Báo cáo khoa học: Fowlicidin-3 is an a-helical cationic host defense peptide with potent antibacterial and lipopolysaccharideneutralizing activities ppt
Tài liệu Báo cáo khoa học: "A Composite Kernel to Extract Relations between Entities with both Flat and Structured Features" ppt
... N1 and N2 are the sets of nodes in trees T1 and T2, respectively, and ()isubtreeIn is a function that is 1 iff the subtreei occurs with root at node n and zero otherwise, and ... viewpoint and report some other observations and issues in our experiments. 5.1 Comparison with Previous Work This is to explain more about why our method performs better and significantly outperforms ... (identi-cal layer and ancestors for the matchable nodes, as discussed in Section 2) in Culotta and Soren-sen (2004). Moreover, the difference between our method and Bunescu and Mooney (2005) is that...
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Tài liệu Báo cáo khoa học: NirF is a periplasmic protein that binds d1 heme as part of its essential role in d1 heme biogenesis pdf
... 252.221.81.41.21.610.80.60.40.20A600A600A600Time (h)Fig. 5. His41 is essential for Paracoc-cus pantotrophus NirF, but Asp129 is dis-pensable. Growth plots and time courses ofnitrite appearance and disappearance forP. pantotrophus SBN11 ... conservedbetween NirF and NirS; it is the His residue that inNirS is the proximal axial ligand to the d1heme.Replacement of an equivalent His, His41, in NirF byAla abolished binding of the ... 5¢ and 3¢ flanking regions ofnirF were cloned and the kanRcassette inserted betweenthem. This was cloned into pJQ200ks (gentamicin-resistant),which is incapable of replication in P. pantotrophus....
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Tài liệu Báo cáo khoa học: Bacitracin is not a specific inhibitor of protein disulfide isomerase pptx
... of PDI, and many have been shown to catalyze thiol–disulfideexchange reactions. However, their specific roles,substrate specificities and mechanisms of cooperation with other catalysts and chaperones ... Bacitracin is not a specific inhibitor of protein disulfideisomeraseAnna-Riikka Karala and Lloyd W. RuddockBiocenter Oulu and Department of Biochemistry, University of Oulu, FinlandIntroductionProtein ... not inhibit the catalysis ofdisulfide bond formation and isomerization by PDIPDI is a catalyst of thiol–disulfide exchange reactions,including oxidation, reduction and isomerization [1].The...
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Tài liệu Báo cáo khoa học: It is all about resolution Meeting report based upon presentations at the 10th International Global BioMillennium 2006 symposium on molecular cell biology (Tbilisi, Georgia) docx
... tumorigenesisThe challenge of cross-platform analysis of cancermicroarray data was presented by Roland Eils (Heidel-berg), who uses median rank scores and quantile dis-cretization to derive numerically ... through membrane blebbing and autophagic cell death. Two closely related kinases,ZIPk and DRP-1, mediate trans-phosphorylation and subsequent functional activation of ZIPk. DAP5 is atranslation ... betweenthe nucleus and cytoplasm is mediated by nuclear porecomplexes, macromolecular assemblies that fuse theinner and outer nuclear membrane and form aqueouschannels for translocation. Ohad...
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Tài liệu Báo cáo khoa học: Expression of an a-1,3-glucanase during mycoparasitic interaction of Trichoderma asperellum docx
... (asperellum and harzianum) could be related todifferences in antagonistic behaviour and ⁄ or host rangebetween these strains and perhaps between the two bio-types. In connection with this idea, it is ... polymers with glycosidic linkages using0.5 mgÆmL)1of each substrate: mutan (a-1,3- and a-1,6-glu-can), nigeran (a-1,3- and a-1,4-glucan), soluble starch(a-1,4- and a-1,6-glucan), pustulan (b-1,6-glucan), ... plates.AcknowledgementsThis work was supported by the Spanish Ministry ofScience and Technology (MCYT), Fundacio´n Ramo´nAreces (Madrid, Spain) and the European Commission(TRICHOEST project). L. Sanz is a...
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Báo cáo khoa học: Visfatin is induced by peroxisome proliferator-activated receptor gamma in human macrophages pdf
... Visfatin ⁄ PBEF ⁄ NAMPT is synthesized and secreted in adipose tissue by adipocytes, and mostlyby macrophages, and circulates in the plasma ofhumans and mice [4]. Plasma concentrations of visfa-tin ... vitro translation and EMSAPPARc and RXRa were in vitro transcribed from thepSG5–hPPARc and pSG5–hRXRa plasmids, respectively,using T7 polymerase, and subsequently translated using thetranscription ... M, Van Gool F, Rongvaux A, Andris F & Leo O(2010) The nicotinamide phosphoribosyltransferase: amolecular link between metabolism, inflammation, and cancer. Cancer Res 70, 8–11.16 Van Ginderachter...
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Báo cáo khoa học: YidC is required for the assembly of the MscL homopentameric pore potx
... 4897AcknowledgementsWe thank Zhong Yu and Edwin van Bloois for helpfuldiscussions, and Sergei Sukharev (Department ofBiology, University of Maryland, MD, USA) for pro-viding MscL plasmids and strains. O.P. is supportedby ... membrane protein biogenesisbecause it is small and, after membrane insertion,assembles into a pentameric complex for which thestructure is known [11,12]. This allows analysis of tar-geting and ... [6]. Hence, it is likely that specificcharacteristics of the transmembrane pairs are also criti-cal for the conditions of membrane insertion.Analysis of the biogenesis of more and more IMPshas...
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Báo cáo khoa học: Lipopolyamine treatment increases the efficacy of intoxication with saporin and an anticancer saporin conjugate doc
... mutant, and the LEX2 mutant were allgrown under humidified conditions at 37 °C and 5% CO2in Ham’s F-12 media (Gibco BRL, Grand Island, NY,USA) supplemented with 10% fetal bovine serum (AtlantaBiologicals, ... for example, is an anticancertoxin that consists of a chemical conjugate between the human uPA and native saporin. Both saporin and uPA-saporin enter the target cell by endo-cytosis and must then ... efficacy ofintoxication with saporin and an anticancer saporinconjugateSandra E. Geden1, Richard A. Gardner2, M. Serena Fabbrini3, Masato Ohashi4, Otto Phanstiel IV2 and Ken Teter11 Department...
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Báo cáo khoa học: Lpx1p is a peroxisomal lipase required for normal peroxisome morphology potx
... membranehydrolysis and prostaglandin production in a mannerdistinct from other intracellular phospholipases A2.J Biol Chem 280, 14028–14041.32 Mancuso DJ, Han X, Jenkins CM, Lehman JJ, Sam-bandam ... versatile and dynamic organelles engaged inthe b-oxidation of long and very long chain fattyacids, in a-oxidation, bile acid and ether lipid synthe-sis, and in amino acid and purine metabolism [1].Peroxisomes ... 5¢-CCCGGGAATGGAACAGAACAGGTTCAAG-3¢ and 5¢-AGATCTTTACAGTTTTTGTTTAGTCGTTTT-3¢, and introduced intopGEM-T (Promega, Mannheim, Germany). The ORF wasexcised using XmaI and BglII, and introduced into pPC86 and pPC97 [35]....
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Báo cáo khoa học: Inhibition of an iron-responsive element/iron regulatory protein-1 complex by ATP binding and hydrolysis docx
... the programprism (GraphPad Software, San Diego, CA).AcknowledgementsThis work was supported by grants from the Heart and Stroke Foundation of Canada (grant T4134) and the Canadian Institutes ... complex by ATP binding and hydrolysisZvezdana Popovic and Douglas M. TempletonLaboratory Medicine and Pathobiology, University of Toronto, CanadaMechanisms of post-transcriptional regulation ... 80% inhibition with recombinant protein, and this difference may arisefrom different characteristics of native HepG2 protein and recombinant protein, such as the presence of aHis-tag on the...
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