Báo cáo khoa học: The fabp4 gene of zebrafish (Danio rerio) ) genomic homology with the mammalian FABP4 and divergence from the zebrafish fabp3 in developmental expression pot

... role in the specificity and affinity of ligand binding by mammalian FABP4 [23]. The phylogenetic relationship of zebrafish fabp4 and the H6-FABP gene from Antarctic fishes was deter- mined using amino ... Alignment of the cDNA sequence with the coding sequence of zebrafish fabp4 showed one nucleotide difference in the coding region of exon 2, resulti...

Ngày tải lên: 07/03/2014, 10:20

... 30821065 and 30870559 from the China National Nature Sciences Foundation, 2006CB910703 from the Ministry of Sciences and Technology of China, and 07dz05907 from the Committee of Sciences and Technology ... 1 lgÆmL )1 insulin, 1 lm dexamethasone, and 0.5 mm 1-methyl-3-isobutylxanthine. The medium was replaced with medium containing 1 lgÆmL )1 insulin aft...

Ngày tải lên: 16/02/2014, 09:20

... rimocidin (C), candidin (D) vacidin A (E). Right: Views of the NMR ensembles, seen along the long axis of the polyene with the D -mycosamine front (indicated with an arrow). The bonds of the hydroxyl ... supporting informa- tion) from the X - PLOR libraries and topology files of different parts of other molecules taken from the Protein Data Bank [49]. For ea...

Ngày tải lên: 21/02/2014, 03:20

... ribonucle- otide binding and radical transfer from the tyrosyl rad- ical (Y12 2) of the R2 subunit to the cysteine (C43 9) found in the active site of the R1 subunit; (b) the abstraction of two protons and water ... of man- ganese in the transcriptional regulation of the nrd operon [35] may not be considered in the light of the results obtaine...

Ngày tải lên: 15/02/2014, 01:20

... the intestine (A), liver (B), ovary (C) and the adrenal homo- log of the fish kidney (D). Panel 2 shows the locations of the distal region of the intestine (A), liver (B), ovary (C) and the adrenal ... distribution and binding activities of FABPs and regulation of FABP genes, including FABP gene knock-out experiments [8], our under- standing of the physiol...

Ngày tải lên: 07/03/2014, 06:20

... of cRBCs within the region of interest is shown in Fig. 3 and the list of important chemical shifts, along with a schematic of protons and probable assignments, is shown in Table S1. Within the ... hemagglutinins as examples. Finally, recent understanding of the role of various glycan structures in high affinity binding to in uenza hemagglutinins provides conte...

Ngày tải lên: 14/02/2014, 19:20

... properties of the minor structural proteins (VP2 and VP 3) of the MPyV were studied in the absence of other virus components as well as during the late phase of virus infection. The role of the minor ... as in the release of virus progeny from infected cells. In the late phase of SV40 infection, production of a late protein, VP4 (125 amino acids f...

Ngày tải lên: 16/02/2014, 09:20

... binding, and indirectly via inter- action with other transcription factors [8,9]. However, even when HD proteins bind their cognate DNA-bind- ing site, they generally bind to other DNA-binding cofactors ... containing either a consensus Meis2-binding and Pbx1-binding site or the Pbx–Hox-bind- ing site from the Hox B1 ARE were phosphorylated with polynucleotide kinase (NE Biolabs...

Ngày tải lên: 16/02/2014, 15:20

... probes 16-doxylstearic acid in the interior of the micelle (A) and Mn 2+ in the aqueous buffer (B) selectively attenuate distinct regions of VpU- cyt, reflecting the topology and the dynamics of the micelle-associ- ated ... into the micelle and are largely shielded from water (green). In contrast, central residues of the interhelical linker extend away fr...

Ngày tải lên: 18/02/2014, 06:20

... of one U by C has no effect on the conversion of others (i.e. formation of pseudouridines at positions 1911, 1915, and 1917 are independent of each other); (c) A1916 is the only position in the ... revealed: (a) RluD isomerizes uridine in vivo only at posi- tions 1911, 1915, and 1917, regardless of the presence of uridine at other positions in the loop of hel...

Ngày tải lên: 18/02/2014, 16:20