Báo cáo khoa học: Conserved structural determinants in three-fingered protein domains pdf

... A, CB a1 is the same atom in the N-terminal cysteine residue in cystine B, CA a2 is the C-terminal cysteine residue in cystine A and CB a2 is the C-terminal cysteine residue in cystine B. A distance ... components of snake venoms forming so-called three-fingered protein domains (TFPDs) are similar to those of the ectodomains of activin, bone morphogenetic protein and trans- formi...

Ngày tải lên: 07/03/2014, 06:20

... hypotheses. As δ increases, we penal- ize long dependenciesless. We call this structural annealing, since we are varying the strength of a soft constraint (bias) on structural hypotheses. In structural ... of picking the right point on the curve to stop. See Table 3 for performance of models selected across smoothing, initializa- tion, starting, and stopping choices, in all six lang...

Ngày tải lên: 17/03/2014, 04:20

... membrane-bound translocation machinery that includes the protein Albino3 [5–9]. The Alb3 protein is related to the Oxa1p and YidC proteins that play important roles in the insertion of proteins into the bacterial ... spontaneous insertion mechan- ism involve binding of the intermediate-size protein to the membrane, after which both hydrophobic domains (one in the signal peptide, t...

Ngày tải lên: 18/03/2014, 01:20

... difficult to find characters that are written in similar ways, e.g., “構” with “購”, in an efficient way. It is intriguing to resort to image processing methods to find such structurally similar ... characters in the right group in the second row in Figure 3 appears in different places in the characters. Lexicographers employ radicals of Chinese characters to organize Chi...

Ngày tải lên: 20/02/2014, 09:20

... Sentence Relation Labeling. In a thread containing N sentences, we would have a 2D CRF containing N 2 nodes in a N × N grid. Exact inference in such a graph is intractable. In this paper we use ... general CRFs. In linear-chain CRF, cliques only involve two adjacent variables in the sequence. Figure 3 shows the graphical structure of a linear-chain CRF. In our case of sentence t...

Ngày tải lên: 07/03/2014, 18:20

... outperforming them as we first hypothesized. And finally, we see again that while in most cases combining speech and lexical features yields better performance than using only speech features, the combined ... human tutoring data, as a step towards understand the dif- ferences between annotating and predicting emotion in human versus computer tutoring dialogues. With respect to inter-annota...

Ngày tải lên: 08/03/2014, 04:22

... unitary digraphs in other languages so these can be used when needed in information processing. (Informa- tion processing is not the shuffling of bits of scribal ink:) The principle does not ... assignments. Information vs. Form. In developing proposals for codes in information processing, the most impor- tant decisions are the choices of what to code. In a proposal for a mu...

Ngày tải lên: 08/03/2014, 18:20

... addressing a single individual. When addressing an individual, people gaze 1.6 times more while listening (62%) than while speaking (40%). When addressing a triad the amount of speaker gaze increases ... related to meeting research that could benefit from studying address- ing in human-human interactions. The results can be used by those who develop communicative agents in interactive inte...

Ngày tải lên: 08/03/2014, 21:20

... Bauer F, Friedrich U, Kardinal C, Feller SM, Biesinger B & Sticht H (2002) Structural investigation of the binding of a herpesviral protein to the SH3 domain of tyrosine kinase Lck. Biochemistry ... trifluoroethanol; VpU, virus protein U; VpUcyt, C-terminal, cytoplasmic domain of VpU (residues 39–81) plus N-terminal Gly-Ser dipeptide; b-TrCP, b-transducin repeat-containing protein;...

Ngày tải lên: 18/02/2014, 06:20

... subdomains within the linker histone H1 0 C-terminal domain. J Biol Chem 279, 8701–8707. 48 Schlessinger A & Rost B (2005) Protein flexibility and rigidity predicted from sequence. Proteins ... compared with the wild-type protein indicates that the structure of the N-terminal domain is maintained, at least in the vicinity of the tryptophan residues. The increase in exposed clustere...

Ngày tải lên: 07/03/2014, 04:20